JPS5785340A - Production of alpha-fluoro-beta-(alkylketo) ester - Google Patents
Production of alpha-fluoro-beta-(alkylketo) esterInfo
- Publication number
- JPS5785340A JPS5785340A JP16013480A JP16013480A JPS5785340A JP S5785340 A JPS5785340 A JP S5785340A JP 16013480 A JP16013480 A JP 16013480A JP 16013480 A JP16013480 A JP 16013480A JP S5785340 A JPS5785340 A JP S5785340A
- Authority
- JP
- Japan
- Prior art keywords
- ester
- formula
- ketone
- alkylketo
- fluoro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: A polyfluoroalkyl ketone, obtained from inexpensively available trifluoroethene, is subjected to dehydrohalogenation and solvolysis in the presence of a basic compound under mild conditions to produce the titled compound used as an intermediate of medicines and agricultural m chemicals.
CONSTITUTION: The dehydrohalogenation and solvolysis of a polyfluoroalkyl ketone of formula I(R is alkyl; X is halogen) such as methyl-2-chloro-1,2,2,- trifluoroethyl-ketone is conducted in the presence of a baseic compound such as an alkoxide or sodium hydroxide in a one-stage process to give α-fluoro-β- (alkylketo) ester of formula II such as α-acetyl-β-fluoroacetic ethyl ester. The starting material of formula Iis obtained by Friedel-Craft reaction of toxicity- free trifluorethene.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16013480A JPS5785340A (en) | 1980-11-13 | 1980-11-13 | Production of alpha-fluoro-beta-(alkylketo) ester |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16013480A JPS5785340A (en) | 1980-11-13 | 1980-11-13 | Production of alpha-fluoro-beta-(alkylketo) ester |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5785340A true JPS5785340A (en) | 1982-05-28 |
JPS6136742B2 JPS6136742B2 (en) | 1986-08-20 |
Family
ID=15708600
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP16013480A Granted JPS5785340A (en) | 1980-11-13 | 1980-11-13 | Production of alpha-fluoro-beta-(alkylketo) ester |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5785340A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010041767A (en) * | 2008-08-01 | 2010-02-18 | Kyosan Electric Mfg Co Ltd | In-vehicle signal display |
-
1980
- 1980-11-13 JP JP16013480A patent/JPS5785340A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010041767A (en) * | 2008-08-01 | 2010-02-18 | Kyosan Electric Mfg Co Ltd | In-vehicle signal display |
Also Published As
Publication number | Publication date |
---|---|
JPS6136742B2 (en) | 1986-08-20 |
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