JPS5762269A - 2,3,5-trisubstituted pyrazine derivative - Google Patents
2,3,5-trisubstituted pyrazine derivativeInfo
- Publication number
- JPS5762269A JPS5762269A JP13776980A JP13776980A JPS5762269A JP S5762269 A JPS5762269 A JP S5762269A JP 13776980 A JP13776980 A JP 13776980A JP 13776980 A JP13776980 A JP 13776980A JP S5762269 A JPS5762269 A JP S5762269A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- alkyl
- formula
- alkali metal
- trisubstituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13776980A JPS5762269A (en) | 1980-10-03 | 1980-10-03 | 2,3,5-trisubstituted pyrazine derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13776980A JPS5762269A (en) | 1980-10-03 | 1980-10-03 | 2,3,5-trisubstituted pyrazine derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5762269A true JPS5762269A (en) | 1982-04-15 |
JPS6148833B2 JPS6148833B2 (enrdf_load_stackoverflow) | 1986-10-25 |
Family
ID=15206394
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP13776980A Granted JPS5762269A (en) | 1980-10-03 | 1980-10-03 | 2,3,5-trisubstituted pyrazine derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5762269A (enrdf_load_stackoverflow) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010055884A1 (ja) * | 2008-11-13 | 2010-05-20 | 日本農薬株式会社 | ピラジン誘導体類の製造方法及びその中間体類 |
JP2021176870A (ja) * | 2016-07-12 | 2021-11-11 | レヴォリューション・メディスンズ,インコーポレイテッド | アロステリックshp2阻害剤としての2,5−二置換3−メチルピラジンおよび2,5,6−三置換3−メチルピラジン |
US11673901B2 (en) | 2017-12-15 | 2023-06-13 | Revolution Medicines, Inc. | Polycyclic compounds as allosteric SHP2 inhibitors |
US11673896B2 (en) | 2017-01-23 | 2023-06-13 | Revolution Medicines, Inc. | Pyridine compounds as allosteric SHP2 inhibitors |
US11702411B2 (en) | 2017-10-12 | 2023-07-18 | Revolution Medicines, Inc. | Pyridine, pyrazine, and triazine compounds as allosteric SHP2 inhibitors |
US11739093B2 (en) | 2017-01-23 | 2023-08-29 | Revolution Medicines, Inc. | Substituted pyrazolopyrazines, imidazopyrazines and [1,2,4]triazolopyrazines as allosteric SHP2 inhibitors |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3931166A (en) * | 1972-04-13 | 1976-01-06 | Firmenich & Cie | Certain 2,5-dimethyl-3-thiopyrazines |
-
1980
- 1980-10-03 JP JP13776980A patent/JPS5762269A/ja active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3931166A (en) * | 1972-04-13 | 1976-01-06 | Firmenich & Cie | Certain 2,5-dimethyl-3-thiopyrazines |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010055884A1 (ja) * | 2008-11-13 | 2010-05-20 | 日本農薬株式会社 | ピラジン誘導体類の製造方法及びその中間体類 |
JP2021176870A (ja) * | 2016-07-12 | 2021-11-11 | レヴォリューション・メディスンズ,インコーポレイテッド | アロステリックshp2阻害剤としての2,5−二置換3−メチルピラジンおよび2,5,6−三置換3−メチルピラジン |
US11673896B2 (en) | 2017-01-23 | 2023-06-13 | Revolution Medicines, Inc. | Pyridine compounds as allosteric SHP2 inhibitors |
US11739093B2 (en) | 2017-01-23 | 2023-08-29 | Revolution Medicines, Inc. | Substituted pyrazolopyrazines, imidazopyrazines and [1,2,4]triazolopyrazines as allosteric SHP2 inhibitors |
US12365688B2 (en) | 2017-01-23 | 2025-07-22 | Revolution Medicines, Inc. | Substituted pyrazolopyrazines, imidazopyrazines and [1,2,4]triazolopyrazines as allosteric SHP2 inhibitors |
US11702411B2 (en) | 2017-10-12 | 2023-07-18 | Revolution Medicines, Inc. | Pyridine, pyrazine, and triazine compounds as allosteric SHP2 inhibitors |
US11673901B2 (en) | 2017-12-15 | 2023-06-13 | Revolution Medicines, Inc. | Polycyclic compounds as allosteric SHP2 inhibitors |
Also Published As
Publication number | Publication date |
---|---|
JPS6148833B2 (enrdf_load_stackoverflow) | 1986-10-25 |
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