JPS5754508B1 - - Google Patents

Info

Publication number
JPS5754508B1
JPS5754508B1 JP46038203A JP3820371A JPS5754508B1 JP S5754508 B1 JPS5754508 B1 JP S5754508B1 JP 46038203 A JP46038203 A JP 46038203A JP 3820371 A JP3820371 A JP 3820371A JP S5754508 B1 JPS5754508 B1 JP S5754508B1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP46038203A
Other languages
Japanese (ja)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS5754508B1 publication Critical patent/JPS5754508B1/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • C07D307/33Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/64Acyl halides
    • C07C57/76Acyl halides containing halogen outside the carbonyl halide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/01Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
    • C07C59/115Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/52Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Apparatuses For Generation Of Mechanical Vibrations (AREA)
JP46038203A 1970-06-01 1971-06-01 Pending JPS5754508B1 (US06573282-20030603-C00015.png)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4253070A 1970-06-01 1970-06-01
US12960771A 1971-03-30 1971-03-30

Publications (1)

Publication Number Publication Date
JPS5754508B1 true JPS5754508B1 (US06573282-20030603-C00015.png) 1982-11-18

Family

ID=26719340

Family Applications (1)

Application Number Title Priority Date Filing Date
JP46038203A Pending JPS5754508B1 (US06573282-20030603-C00015.png) 1970-06-01 1971-06-01

Country Status (18)

Country Link
JP (1) JPS5754508B1 (US06573282-20030603-C00015.png)
AT (1) AT312606B (US06573282-20030603-C00015.png)
BE (1) BE767798A (US06573282-20030603-C00015.png)
CH (2) CH553182A (US06573282-20030603-C00015.png)
CS (1) CS171232B2 (US06573282-20030603-C00015.png)
DE (2) DE2167193C2 (US06573282-20030603-C00015.png)
DK (1) DK137382B (US06573282-20030603-C00015.png)
ES (1) ES391633A1 (US06573282-20030603-C00015.png)
FI (1) FI54472C (US06573282-20030603-C00015.png)
FR (1) FR2100711B1 (US06573282-20030603-C00015.png)
GB (1) GB1319040A (US06573282-20030603-C00015.png)
HK (1) HK78076A (US06573282-20030603-C00015.png)
HU (1) HU166420B (US06573282-20030603-C00015.png)
IL (1) IL36949A (US06573282-20030603-C00015.png)
NL (1) NL173848C (US06573282-20030603-C00015.png)
NO (1) NO133547C (US06573282-20030603-C00015.png)
PL (1) PL81548B1 (US06573282-20030603-C00015.png)
SE (1) SE369418B (US06573282-20030603-C00015.png)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2141810A1 (en) * 1992-08-05 1994-02-17 Ian A. Cliffe Amide derivatives
US6190691B1 (en) 1994-04-12 2001-02-20 Adolor Corporation Methods for treating inflammatory conditions
US5962477A (en) 1994-04-12 1999-10-05 Adolor Corporation Screening methods for cytokine inhibitors
US5434158A (en) * 1994-04-26 1995-07-18 Merck & Co., Inc. Spiro-substituted azacycles as neurokinin-3 antagonists
GB9502644D0 (en) * 1995-02-10 1995-03-29 Zeneca Ltd Heterocyclic derivatives
US5849761A (en) * 1995-09-12 1998-12-15 Regents Of The University Of California Peripherally active anti-hyperalgesic opiates
US6573282B1 (en) 1995-09-12 2003-06-03 Adolor Corporation Peripherally active anti-hyperalgesic opiates
WO1997024325A1 (en) * 1995-12-28 1997-07-10 Takeda Chemical Industries, Ltd. DIPHENYLMETHANE DERIVATIVES AS MIP-1α/RANTES RECEPTOR ANTAGONISTS
EP2266590A3 (en) 2002-02-22 2011-04-20 Shire LLC Active agent delivery sytems and methods for protecting and administering active agents
CN110357808A (zh) * 2019-06-13 2019-10-22 上海上药新亚药业有限公司 一种盐酸洛哌丁胺的结晶工艺

Also Published As

Publication number Publication date
CH549015A (fr) 1974-05-15
FR2100711A1 (US06573282-20030603-C00015.png) 1972-03-24
DE2126559A1 (de) 1972-10-05
BE767798A (fr) 1971-11-29
CH553182A (fr) 1974-08-30
NO133547B (US06573282-20030603-C00015.png) 1976-02-09
IL36949A0 (en) 1971-07-28
DE2126559C3 (de) 1982-01-14
FI54472C (fi) 1978-12-11
CS171232B2 (en) 1976-10-31
NL173848C (nl) 1984-03-16
DK137382C (US06573282-20030603-C00015.png) 1978-08-07
SE369418B (US06573282-20030603-C00015.png) 1974-08-26
IL36949A (en) 1974-07-31
DE2126559B2 (de) 1981-02-26
FR2100711B1 (US06573282-20030603-C00015.png) 1974-09-27
DK137382B (da) 1978-02-27
HU166420B (US06573282-20030603-C00015.png) 1975-03-28
NL7106829A (US06573282-20030603-C00015.png) 1971-12-03
ES391633A1 (es) 1975-09-16
NO133547C (US06573282-20030603-C00015.png) 1976-05-19
PL81548B1 (en) 1975-08-30
AT312606B (de) 1974-01-10
GB1319040A (en) 1973-05-31
DE2167193C2 (de) 1983-05-19
FI54472B (fi) 1978-08-31
HK78076A (en) 1976-12-17

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