JPS5748986A - Production of cephalosporanic acid - Google Patents

Production of cephalosporanic acid

Info

Publication number
JPS5748986A
JPS5748986A JP12347580A JP12347580A JPS5748986A JP S5748986 A JPS5748986 A JP S5748986A JP 12347580 A JP12347580 A JP 12347580A JP 12347580 A JP12347580 A JP 12347580A JP S5748986 A JPS5748986 A JP S5748986A
Authority
JP
Japan
Prior art keywords
reaction
formula
diazin
aminocephalosporanic
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP12347580A
Other languages
Japanese (ja)
Inventor
Masahiro Murakami
Masateru Kobayashi
Kimiyo Yamamoto
Kazuyuki Shibuya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Corp
Asahi Chemical Industry Co Ltd
Original Assignee
Asahi Chemical Industry Co Ltd
Asahi Kasei Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Industry Co Ltd, Asahi Kasei Kogyo KK filed Critical Asahi Chemical Industry Co Ltd
Priority to JP12347580A priority Critical patent/JPS5748986A/en
Publication of JPS5748986A publication Critical patent/JPS5748986A/en
Pending legal-status Critical Current

Links

Abstract

PURPOSE: The reaction of 7-aminocephalosporanic derivative with 3-hydroxy-1,2- diazin-6-ylthiol mandelate gives the titled compound used as an antibiotic in high safety and high yield.
CONSTITUTION: A 7-aminocephalosporanic derivative of formula I (R1 is halogen, azide, acetoxy, banzimidazolthio) such as 7-amino-3-(benzimidazol-2-yl)thiomethyl- 3-cephem-4-carboxylic acid is heated in dimethylformamide and water and 3-hydroxy-1,2-diazin-6-yl-thiol madelate of formula II and dilute hydrochloric acid as a reaction catalyst are added to the mixture to effect the reaction, thus producing objective compound of formula III.
COPYRIGHT: (C)1982,JPO&Japio
JP12347580A 1980-09-08 1980-09-08 Production of cephalosporanic acid Pending JPS5748986A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12347580A JPS5748986A (en) 1980-09-08 1980-09-08 Production of cephalosporanic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12347580A JPS5748986A (en) 1980-09-08 1980-09-08 Production of cephalosporanic acid

Publications (1)

Publication Number Publication Date
JPS5748986A true JPS5748986A (en) 1982-03-20

Family

ID=14861541

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12347580A Pending JPS5748986A (en) 1980-09-08 1980-09-08 Production of cephalosporanic acid

Country Status (1)

Country Link
JP (1) JPS5748986A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU587974B2 (en) * 1984-03-29 1989-09-07 Biochemie Gesellschaft Mbh Process for preparation of cephalosporins

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU587974B2 (en) * 1984-03-29 1989-09-07 Biochemie Gesellschaft Mbh Process for preparation of cephalosporins

Similar Documents

Publication Publication Date Title
SE8403896L (en) ANTIBIOTICS
US3544581A (en) Production of 6-amino-penicillanic acid sulfoxide
ES412859A1 (en) Process for preparing 7-(alpha-hydroxy-alpha-phenyl)acetamido-3-(1-methyl-1h-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid and derivatives thereof
JPS54119494A (en) Preparation of cephalosporin compound
JPS5748986A (en) Production of cephalosporanic acid
JPS57192392A (en) Production of 3-alkoxymethylcephalosporin
JPS5746990A (en) Novel cephalexin derivative and its preparation
JPS5795992A (en) Novel derivative of cephamycin c and its preparation
JPS5653684A (en) Production of cephalosporin derivative
JPS56133293A (en) Novel preparation of cephalosporanic acid derivative
JPS5746989A (en) Preparation of cephalosporanic acid compound
US3880837A (en) 6-Hydrazono penicillins and method of preparation thereof
JPS577438A (en) Production of acid chloride
JPS5772987A (en) Production of cephalosporanic acid derivative
SU133880A1 (en) Method for preparing dialkyl or alkyl-alkoxydithiophosphinic acid aryl esters
JPS56135489A (en) Preparative method of cephalosporanic acid derivative
JPS5716882A (en) Production of benzo-heteroring derivative
JPS5547651A (en) Production of sulfoxyimine
JPS56152485A (en) Production of cephapirin
JPS55124781A (en) 1,4-benzdioxanesulfonamide derivative
JPS55122788A (en) Preparation of cephalosporin compound
JPS6413072A (en) Production of 3-alkoxy-5-amino-1h-pyrazoles
JPS5673086A (en) Preparation of cephalosporin compound
JPS5758689A (en) Novel preparation of 7-substituted or unsubstituted amino-3-substituted methylcephem carboxylic acids
JPS5527111A (en) Preparation of cephapirin