JPS5748972A - 4-phenylphthalazine derivative - Google Patents
4-phenylphthalazine derivativeInfo
- Publication number
- JPS5748972A JPS5748972A JP12464480A JP12464480A JPS5748972A JP S5748972 A JPS5748972 A JP S5748972A JP 12464480 A JP12464480 A JP 12464480A JP 12464480 A JP12464480 A JP 12464480A JP S5748972 A JPS5748972 A JP S5748972A
- Authority
- JP
- Japan
- Prior art keywords
- derivative shown
- formula
- phenylphthalazine
- phenylphthalazine derivative
- cerebral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- KHIILJVSYUGMSE-UHFFFAOYSA-N 1-phenylphthalazine Chemical class C1=CC=CC=C1C1=NN=CC2=CC=CC=C12 KHIILJVSYUGMSE-UHFFFAOYSA-N 0.000 title abstract 2
- WJJDLSHYLZRFDD-UHFFFAOYSA-N 1-chloro-4-phenylphthalazine Chemical class C12=CC=CC=C2C(Cl)=NN=C1C1=CC=CC=C1 WJJDLSHYLZRFDD-UHFFFAOYSA-N 0.000 abstract 1
- 206010008132 Cerebral thrombosis Diseases 0.000 abstract 1
- 201000001429 Intracranial Thrombosis Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001448 anilines Chemical class 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 206010008118 cerebral infarction Diseases 0.000 abstract 1
- 208000026106 cerebrovascular disease Diseases 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 208000010125 myocardial infarction Diseases 0.000 abstract 1
- RERYBIJRZCOTDV-UHFFFAOYSA-N n-(3-chlorophenyl)-4-(4-methylphenyl)phthalazin-1-amine Chemical compound C1=CC(C)=CC=C1C(C1=CC=CC=C11)=NN=C1NC1=CC=CC(Cl)=C1 RERYBIJRZCOTDV-UHFFFAOYSA-N 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12464480A JPS5748972A (en) | 1980-09-10 | 1980-09-10 | 4-phenylphthalazine derivative |
| GB8030906A GB2063249A (en) | 1979-10-09 | 1980-09-25 | 4-Phenylphthalazine derivatives |
| NL8005411A NL8005411A (nl) | 1979-10-09 | 1980-09-30 | 4-fenylftalazinederivaten. |
| IT25206/80A IT1148727B (it) | 1979-10-09 | 1980-10-08 | Derivati di 4-fenil-ftalazine ad azione terapeutica |
| FR8021530A FR2468593A1 (fr) | 1979-10-09 | 1980-10-08 | Derives de 4-phenylphtalazine utilisables comme medicaments inhibiteurs de l'agregation de plaquettes sanguines, et procede pour leur preparation |
| DE19803038166 DE3038166A1 (de) | 1979-10-09 | 1980-10-09 | 4-phenylphthalazinderivate und verfahren zu deren herstellung, sowie arzneimittel, welche diese enthalten |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12464480A JPS5748972A (en) | 1980-09-10 | 1980-09-10 | 4-phenylphthalazine derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5748972A true JPS5748972A (en) | 1982-03-20 |
| JPS6334871B2 JPS6334871B2 (enrdf_load_stackoverflow) | 1988-07-12 |
Family
ID=14890500
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP12464480A Granted JPS5748972A (en) | 1979-10-09 | 1980-09-10 | 4-phenylphthalazine derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5748972A (enrdf_load_stackoverflow) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5324727A (en) * | 1991-09-26 | 1994-06-28 | Mitsubishi Chem Ind | 3,6-disubstituted pyridazine derivatives |
| EP0682947A1 (en) | 1994-05-19 | 1995-11-22 | Mitsubishi Chemical Corporation | Medicament for therapeutic and prophylactic treatment of diseases caused by smooth muscle cell hyperplasia |
| JP2007536276A (ja) * | 2004-05-08 | 2007-12-13 | ニューロジェン・コーポレーション | ３−アリール−５，６−ジ置換ピリダジン類 |
| KR20180046904A (ko) * | 2016-10-28 | 2018-05-09 | 주식회사 대웅제약 | 페닐 프탈라진 유도체, 이의 제조 방법 및 이를 포함하는 약학적 조성물 |
-
1980
- 1980-09-10 JP JP12464480A patent/JPS5748972A/ja active Granted
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5324727A (en) * | 1991-09-26 | 1994-06-28 | Mitsubishi Chem Ind | 3,6-disubstituted pyridazine derivatives |
| US5462941A (en) * | 1991-09-26 | 1995-10-31 | Mitsubishi Chemical Corporation | 3,6-disubstituted pyradazine derivatives |
| EP0682947A1 (en) | 1994-05-19 | 1995-11-22 | Mitsubishi Chemical Corporation | Medicament for therapeutic and prophylactic treatment of diseases caused by smooth muscle cell hyperplasia |
| JP2007536276A (ja) * | 2004-05-08 | 2007-12-13 | ニューロジェン・コーポレーション | ３−アリール−５，６−ジ置換ピリダジン類 |
| KR20180046904A (ko) * | 2016-10-28 | 2018-05-09 | 주식회사 대웅제약 | 페닐 프탈라진 유도체, 이의 제조 방법 및 이를 포함하는 약학적 조성물 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6334871B2 (enrdf_load_stackoverflow) | 1988-07-12 |
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