JPS5746985A - Preparation of antibiotic - Google Patents
Preparation of antibioticInfo
- Publication number
- JPS5746985A JPS5746985A JP55123087A JP12308780A JPS5746985A JP S5746985 A JPS5746985 A JP S5746985A JP 55123087 A JP55123087 A JP 55123087A JP 12308780 A JP12308780 A JP 12308780A JP S5746985 A JPS5746985 A JP S5746985A
- Authority
- JP
- Japan
- Prior art keywords
- antibiotic
- formula
- substance
- hydrolyzing
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000003115 biocidal effect Effects 0.000 title 1
- 239000000126 substance Substances 0.000 abstract 4
- FWWJFXYMDLTDNO-BBCPMLLOSA-N (5r,6r)-3-[(r)-[(e)-2-acetamidoethenyl]sulfinyl]-6-(2-hydroxypropan-2-yl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid Chemical compound C1C([S@](=O)/C=C/NC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](C(C)(C)O)[C@@H]12 FWWJFXYMDLTDNO-BBCPMLLOSA-N 0.000 abstract 3
- GOODEIVATWULQD-CWYJLJPQSA-N (5r,6r)-3-[(r)-[(e)-2-acetamidoethenyl]sulfinyl]-7-oxo-6-(2-sulfooxypropan-2-yl)-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid Chemical compound C1C([S@](=O)/C=C/NC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](C(C)(C)OS(O)(=O)=O)[C@@H]12 GOODEIVATWULQD-CWYJLJPQSA-N 0.000 abstract 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- 230000003301 hydrolyzing effect Effects 0.000 abstract 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- 244000005700 microbiome Species 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
- 241000187747 Streptomyces Species 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 229920001429 chelating resin Polymers 0.000 abstract 1
- 239000012531 culture fluid Substances 0.000 abstract 1
- 239000000706 filtrate Substances 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 239000003456 ion exchange resin Substances 0.000 abstract 1
- 229920003303 ion-exchange polymer Polymers 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/02—Preparation
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55123087A JPS5746985A (en) | 1980-09-05 | 1980-09-05 | Preparation of antibiotic |
US06/296,306 US4415497A (en) | 1980-09-05 | 1981-08-26 | Process for producing an antibiotic |
AT81303921T ATE10281T1 (de) | 1980-09-05 | 1981-08-27 | Verfahren zur herstellung eines antibiotikums. |
EP81303921A EP0047611B1 (en) | 1980-09-05 | 1981-08-27 | Process for producing an antibiotic |
DE8181303921T DE3167215D1 (en) | 1980-09-05 | 1981-08-27 | Process for producing an antibiotic |
ES505203A ES8306505A1 (es) | 1980-09-05 | 1981-09-04 | Proceso para producir en un antibiotico ka-6643-a. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55123087A JPS5746985A (en) | 1980-09-05 | 1980-09-05 | Preparation of antibiotic |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5746985A true JPS5746985A (en) | 1982-03-17 |
JPS6254426B2 JPS6254426B2 (ja) | 1987-11-14 |
Family
ID=14851878
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55123087A Granted JPS5746985A (en) | 1980-09-05 | 1980-09-05 | Preparation of antibiotic |
Country Status (6)
Country | Link |
---|---|
US (1) | US4415497A (ja) |
EP (1) | EP0047611B1 (ja) |
JP (1) | JPS5746985A (ja) |
AT (1) | ATE10281T1 (ja) |
DE (1) | DE3167215D1 (ja) |
ES (1) | ES8306505A1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0197536A (ja) * | 1987-10-09 | 1989-04-17 | Hitachi Seiki Co Ltd | 自動工具交換装置 |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4497742A (en) * | 1981-03-04 | 1985-02-05 | Takeda Chemical Industries, Ltd. | Isomerization of β-lactam compounds |
GB8619683D0 (en) * | 1986-08-13 | 1986-09-24 | Unilever Plc | Particulate ingredient |
DE69100244T2 (de) * | 1990-03-21 | 1994-01-13 | Unilever Nv | Beutel und Verpackungsverfahren. |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4211707A (en) * | 1978-08-10 | 1980-07-08 | Merck & Co., Inc. | Process for hydrolytically cleaving O-sulfo thienamycins |
AU534530B2 (en) * | 1979-02-02 | 1984-02-02 | Takeda Chemical Industries Ltd. | 5-aza-(3.2.0)-heptane derivatives |
-
1980
- 1980-09-05 JP JP55123087A patent/JPS5746985A/ja active Granted
-
1981
- 1981-08-26 US US06/296,306 patent/US4415497A/en not_active Expired - Fee Related
- 1981-08-27 DE DE8181303921T patent/DE3167215D1/de not_active Expired
- 1981-08-27 AT AT81303921T patent/ATE10281T1/de active
- 1981-08-27 EP EP81303921A patent/EP0047611B1/en not_active Expired
- 1981-09-04 ES ES505203A patent/ES8306505A1/es not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0197536A (ja) * | 1987-10-09 | 1989-04-17 | Hitachi Seiki Co Ltd | 自動工具交換装置 |
Also Published As
Publication number | Publication date |
---|---|
EP0047611B1 (en) | 1984-11-14 |
US4415497A (en) | 1983-11-15 |
EP0047611A1 (en) | 1982-03-17 |
ATE10281T1 (de) | 1984-11-15 |
JPS6254426B2 (ja) | 1987-11-14 |
ES505203A0 (es) | 1983-06-01 |
ES8306505A1 (es) | 1983-06-01 |
DE3167215D1 (en) | 1984-12-20 |
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