JPS57197297A - Preparation of antibiotic - Google Patents
Preparation of antibioticInfo
- Publication number
- JPS57197297A JPS57197297A JP8187481A JP8187481A JPS57197297A JP S57197297 A JPS57197297 A JP S57197297A JP 8187481 A JP8187481 A JP 8187481A JP 8187481 A JP8187481 A JP 8187481A JP S57197297 A JPS57197297 A JP S57197297A
- Authority
- JP
- Japan
- Prior art keywords
- culture
- acid
- accumulating
- bacterium
- give
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
PURPOSE: To obtain a 16-membered ring macrolide type antibiotic in high yield, useful as an antibacterial agnet, etc., by cultivating a bacterium bleonging to the genus Streptomyces in a nutritive medium to form a culture accumulating a specific compound, treating a solution containing the culture with an acid.
CONSTITUTION: A bacterium such as Streptomyces fradiae strain YT-3927 belonging to the genus Streptomyces is cultivated in a nutritive medium to form a culture accumulating a compound shown by the formulaI(R is H or hydroxyl group), and a solution contaning the culture is reacted with an acid(e.g., hydrochloric acid, etc.), to give 23-deoxymycaminosyl tylonolide shown by the formula II. The mold is removed from the reaction solution, which is adjusted to a proper pH, extracted, and the extract is concentrated to dryness under reduced pressure, to give the desired compound.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8187481A JPS57197297A (en) | 1981-05-30 | 1981-05-30 | Preparation of antibiotic |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8187481A JPS57197297A (en) | 1981-05-30 | 1981-05-30 | Preparation of antibiotic |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57197297A true JPS57197297A (en) | 1982-12-03 |
Family
ID=13758600
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP8187481A Pending JPS57197297A (en) | 1981-05-30 | 1981-05-30 | Preparation of antibiotic |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57197297A (en) |
-
1981
- 1981-05-30 JP JP8187481A patent/JPS57197297A/en active Pending
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