JPS57197297A - Preparation of antibiotic - Google Patents

Preparation of antibiotic

Info

Publication number
JPS57197297A
JPS57197297A JP8187481A JP8187481A JPS57197297A JP S57197297 A JPS57197297 A JP S57197297A JP 8187481 A JP8187481 A JP 8187481A JP 8187481 A JP8187481 A JP 8187481A JP S57197297 A JPS57197297 A JP S57197297A
Authority
JP
Japan
Prior art keywords
culture
acid
accumulating
bacterium
give
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8187481A
Other languages
Japanese (ja)
Inventor
Rokuro Okamoto
Masao Yamamoto
Kazuaki Takada
Michinori Kiyoshima
Tomoyuki Ishikura
Hamao Umezawa
Tomio Takeuchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SANRAKU OCEAN KK
Sanraku Inc
Sanraku Ocean Co Ltd
Original Assignee
SANRAKU OCEAN KK
Sanraku Inc
Sanraku Ocean Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SANRAKU OCEAN KK, Sanraku Inc, Sanraku Ocean Co Ltd filed Critical SANRAKU OCEAN KK
Priority to JP8187481A priority Critical patent/JPS57197297A/en
Publication of JPS57197297A publication Critical patent/JPS57197297A/en
Pending legal-status Critical Current

Links

Abstract

PURPOSE: To obtain a 16-membered ring macrolide type antibiotic in high yield, useful as an antibacterial agnet, etc., by cultivating a bacterium bleonging to the genus Streptomyces in a nutritive medium to form a culture accumulating a specific compound, treating a solution containing the culture with an acid.
CONSTITUTION: A bacterium such as Streptomyces fradiae strain YT-3927 belonging to the genus Streptomyces is cultivated in a nutritive medium to form a culture accumulating a compound shown by the formulaI(R is H or hydroxyl group), and a solution contaning the culture is reacted with an acid(e.g., hydrochloric acid, etc.), to give 23-deoxymycaminosyl tylonolide shown by the formula II. The mold is removed from the reaction solution, which is adjusted to a proper pH, extracted, and the extract is concentrated to dryness under reduced pressure, to give the desired compound.
COPYRIGHT: (C)1982,JPO&Japio
JP8187481A 1981-05-30 1981-05-30 Preparation of antibiotic Pending JPS57197297A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8187481A JPS57197297A (en) 1981-05-30 1981-05-30 Preparation of antibiotic

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8187481A JPS57197297A (en) 1981-05-30 1981-05-30 Preparation of antibiotic

Publications (1)

Publication Number Publication Date
JPS57197297A true JPS57197297A (en) 1982-12-03

Family

ID=13758600

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8187481A Pending JPS57197297A (en) 1981-05-30 1981-05-30 Preparation of antibiotic

Country Status (1)

Country Link
JP (1) JPS57197297A (en)

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