JPS5746977A - Novel prostacyclin and its preparation - Google Patents
Novel prostacyclin and its preparationInfo
- Publication number
- JPS5746977A JPS5746977A JP12121080A JP12121080A JPS5746977A JP S5746977 A JPS5746977 A JP S5746977A JP 12121080 A JP12121080 A JP 12121080A JP 12121080 A JP12121080 A JP 12121080A JP S5746977 A JPS5746977 A JP S5746977A
- Authority
- JP
- Japan
- Prior art keywords
- prostacyclin
- agent
- expressed
- formula
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229960001123 epoprostenol Drugs 0.000 title abstract 4
- KAQKFAOMNZTLHT-VVUHWYTRSA-N epoprostenol Chemical compound O1C(=CCCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 KAQKFAOMNZTLHT-VVUHWYTRSA-N 0.000 title 1
- KAQKFAOMNZTLHT-OZUDYXHBSA-N prostaglandin I2 Chemical compound O1\C(=C/CCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 KAQKFAOMNZTLHT-OZUDYXHBSA-N 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 239000000924 antiasthmatic agent Substances 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 239000003699 antiulcer agent Substances 0.000 abstract 1
- 150000001735 carboxylic acids Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 150000004702 methyl esters Chemical class 0.000 abstract 1
- 125000001181 organosilyl group Chemical group [SiH3]* 0.000 abstract 1
- JUJWROOIHBZHMG-UHFFFAOYSA-N pyridine Substances C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- FGTJJHCZWOVVNH-UHFFFAOYSA-N tert-butyl-[tert-butyl(dimethyl)silyl]oxy-dimethylsilane Chemical compound CC(C)(C)[Si](C)(C)O[Si](C)(C)C(C)(C)C FGTJJHCZWOVVNH-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12121080A JPS5746977A (en) | 1980-09-03 | 1980-09-03 | Novel prostacyclin and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12121080A JPS5746977A (en) | 1980-09-03 | 1980-09-03 | Novel prostacyclin and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5746977A true JPS5746977A (en) | 1982-03-17 |
| JPH026754B2 JPH026754B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1990-02-13 |
Family
ID=14805595
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP12121080A Granted JPS5746977A (en) | 1980-09-03 | 1980-09-03 | Novel prostacyclin and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5746977A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5799580A (en) * | 1980-10-27 | 1982-06-21 | Chinoin Gyogyszer Es Vegyeszet | 7-substituted pgi2 derivative and manufacture |
| JPS59185533A (ja) * | 1983-04-07 | 1984-10-22 | Honda Motor Co Ltd | バルブラツシユアジヤスタ用プランジヤの製造方法 |
| JPS59185534A (ja) * | 1983-04-07 | 1984-10-22 | Honda Motor Co Ltd | バルブラツシユアジヤスタ用プランジヤの製造方法 |
| JPS59209440A (ja) * | 1983-05-12 | 1984-11-28 | Honda Motor Co Ltd | バルブラツシユアジヤスタ用プランジヤの製造方法 |
| JPS60106635A (ja) * | 1983-11-14 | 1985-06-12 | Honda Motor Co Ltd | エンジン用プツシユロツドの製造方法 |
| JP2012503143A (ja) * | 2008-09-23 | 2012-02-02 | イートン コーポレーション | 油圧式ラッシュアジャスターに使用するボールプランジャー及び該ボールプランジャーの製造方法 |
-
1980
- 1980-09-03 JP JP12121080A patent/JPS5746977A/ja active Granted
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5799580A (en) * | 1980-10-27 | 1982-06-21 | Chinoin Gyogyszer Es Vegyeszet | 7-substituted pgi2 derivative and manufacture |
| JPS59185533A (ja) * | 1983-04-07 | 1984-10-22 | Honda Motor Co Ltd | バルブラツシユアジヤスタ用プランジヤの製造方法 |
| JPS59185534A (ja) * | 1983-04-07 | 1984-10-22 | Honda Motor Co Ltd | バルブラツシユアジヤスタ用プランジヤの製造方法 |
| JPS59209440A (ja) * | 1983-05-12 | 1984-11-28 | Honda Motor Co Ltd | バルブラツシユアジヤスタ用プランジヤの製造方法 |
| JPS60106635A (ja) * | 1983-11-14 | 1985-06-12 | Honda Motor Co Ltd | エンジン用プツシユロツドの製造方法 |
| JP2012503143A (ja) * | 2008-09-23 | 2012-02-02 | イートン コーポレーション | 油圧式ラッシュアジャスターに使用するボールプランジャー及び該ボールプランジャーの製造方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH026754B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1990-02-13 |
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