JPS57200366A - Isoquinoline compound - Google Patents
Isoquinoline compoundInfo
- Publication number
- JPS57200366A JPS57200366A JP56082559A JP8255981A JPS57200366A JP S57200366 A JPS57200366 A JP S57200366A JP 56082559 A JP56082559 A JP 56082559A JP 8255981 A JP8255981 A JP 8255981A JP S57200366 A JPS57200366 A JP S57200366A
- Authority
- JP
- Japan
- Prior art keywords
- formulai
- remedy
- compound
- cerebral
- isoquinoline compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 Isoquinoline compound Chemical class 0.000 title abstract 2
- AWJUIBRHMBBTKR-UHFFFAOYSA-N iso-quinoline Natural products C1=NC=CC2=CC=CC=C21 AWJUIBRHMBBTKR-UHFFFAOYSA-N 0.000 title abstract 2
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 230000002490 cerebral effect Effects 0.000 abstract 2
- 206010002383 Angina Pectoris Diseases 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 210000000748 cardiovascular system Anatomy 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 230000001965 increasing effect Effects 0.000 abstract 1
- BFIWZEKPARJYJE-UHFFFAOYSA-N isoquinoline-5-sulfonamide Chemical compound N1=CC=C2C(S(=O)(=O)N)=CC=CC2=C1 BFIWZEKPARJYJE-UHFFFAOYSA-N 0.000 abstract 1
- WHIDHHUCCTYJKA-UHFFFAOYSA-N isoquinoline-5-sulfonyl chloride Chemical compound N1=CC=C2C(S(=O)(=O)Cl)=CC=CC2=C1 WHIDHHUCCTYJKA-UHFFFAOYSA-N 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000002040 relaxant effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 210000002460 smooth muscle Anatomy 0.000 abstract 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 abstract 1
- 235000017557 sodium bicarbonate Nutrition 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 229940124549 vasodilator Drugs 0.000 abstract 1
- 239000003071 vasodilator agent Substances 0.000 abstract 1
Landscapes
- Other In-Based Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56082559A JPS57200366A (en) | 1981-06-01 | 1981-06-01 | Isoquinoline compound |
| US06/357,770 US4456757A (en) | 1981-03-20 | 1982-03-12 | Isoquinolinesulfonyl derivatives and process for the preparation thereof |
| DE8282102291T DE3261029D1 (en) | 1981-03-20 | 1982-03-19 | Isoquinolinesulfonyl derivatives and process for the preparation thereof |
| EP82102291A EP0061673B1 (en) | 1981-03-20 | 1982-03-19 | Isoquinolinesulfonyl derivatives and process for the preparation thereof |
| US06/572,419 US4560755A (en) | 1981-03-20 | 1984-01-20 | Isoquinolinesulfonyl derivatives which possess a relaxatory action |
| US06/572,418 US4525589A (en) | 1981-03-20 | 1984-01-20 | Isoquinolinesulfonyl derivatives |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56082559A JPS57200366A (en) | 1981-06-01 | 1981-06-01 | Isoquinoline compound |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS57200366A true JPS57200366A (en) | 1982-12-08 |
| JPS6361942B2 JPS6361942B2 (enrdf_load_html_response) | 1988-11-30 |
Family
ID=13777844
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP56082559A Granted JPS57200366A (en) | 1981-03-20 | 1981-06-01 | Isoquinoline compound |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS57200366A (enrdf_load_html_response) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61227581A (ja) * | 1985-04-02 | 1986-10-09 | Asahi Chem Ind Co Ltd | 血管拡張剤 |
| WO1998006433A1 (fr) | 1996-08-12 | 1998-02-19 | Yoshitomi Pharmaceutical Industries, Ltd. | MEDICAMENTS COMPRENANT UN INHIBITEUR DE LA Rho KINASE |
| WO2000064478A1 (fr) | 1999-04-27 | 2000-11-02 | Mitsubishi Pharma Corporation | Medicaments destines a soigner et a prevenir les maladies du foie |
| JP2006063018A (ja) * | 2004-08-27 | 2006-03-09 | Asahi Kasei Fainkemu Kk | イソキノリンスルホニルクロリドの製造方法 |
| JP2006076932A (ja) * | 2004-09-10 | 2006-03-23 | Asahi Kasei Fainkemu Kk | イソキノリンスルホニルクロリドの製造方法 |
| WO2009004792A1 (ja) * | 2007-07-02 | 2009-01-08 | Asahi Kasei Pharma Corporation | スルホンアミド化合物及びその結晶 |
| US7618984B2 (en) | 2005-08-30 | 2009-11-17 | Asahi Kasei Pharma Corporation | Sulfonamide compound |
| US7964613B2 (en) | 2007-02-28 | 2011-06-21 | Asahi Kasei Pharma Corporation | Sulfonamide compound |
| US8415372B2 (en) | 2007-02-27 | 2013-04-09 | Asahi Kasei Pharma Corporation | Sulfonamide compound |
-
1981
- 1981-06-01 JP JP56082559A patent/JPS57200366A/ja active Granted
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61227581A (ja) * | 1985-04-02 | 1986-10-09 | Asahi Chem Ind Co Ltd | 血管拡張剤 |
| CZ301044B6 (cs) * | 1996-08-12 | 2009-10-21 | Mitsubishi Tanabe Pharma | Léciva obsahující amidové deriváty inhibující Rho kinázu |
| WO1998006433A1 (fr) | 1996-08-12 | 1998-02-19 | Yoshitomi Pharmaceutical Industries, Ltd. | MEDICAMENTS COMPRENANT UN INHIBITEUR DE LA Rho KINASE |
| WO2000064478A1 (fr) | 1999-04-27 | 2000-11-02 | Mitsubishi Pharma Corporation | Medicaments destines a soigner et a prevenir les maladies du foie |
| JP2006063018A (ja) * | 2004-08-27 | 2006-03-09 | Asahi Kasei Fainkemu Kk | イソキノリンスルホニルクロリドの製造方法 |
| JP2006076932A (ja) * | 2004-09-10 | 2006-03-23 | Asahi Kasei Fainkemu Kk | イソキノリンスルホニルクロリドの製造方法 |
| US7618984B2 (en) | 2005-08-30 | 2009-11-17 | Asahi Kasei Pharma Corporation | Sulfonamide compound |
| US8415372B2 (en) | 2007-02-27 | 2013-04-09 | Asahi Kasei Pharma Corporation | Sulfonamide compound |
| US7964613B2 (en) | 2007-02-28 | 2011-06-21 | Asahi Kasei Pharma Corporation | Sulfonamide compound |
| WO2009004792A1 (ja) * | 2007-07-02 | 2009-01-08 | Asahi Kasei Pharma Corporation | スルホンアミド化合物及びその結晶 |
| US8232292B2 (en) | 2007-07-02 | 2012-07-31 | Asahi Kasei Pharma Corporation | Sulfonamide compound and crystal thereof |
| JP2012236858A (ja) * | 2007-07-02 | 2012-12-06 | Asahi Kasei Pharma Kk | スルホンアミド化合物塩の製造方法 |
| JP5234825B2 (ja) * | 2007-07-02 | 2013-07-10 | 旭化成ファーマ株式会社 | スルホンアミド化合物及びその結晶 |
| US8664243B2 (en) | 2007-07-02 | 2014-03-04 | Asahi Kasei Pharma Corporation | Sulfonamide compound and crystal thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6361942B2 (enrdf_load_html_response) | 1988-11-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPS57200366A (en) | Isoquinoline compound | |
| JPS57156463A (en) | Isoquinoline derivative | |
| JPS53119866A (en) | 5-aryloxy-oxazoleakanoic acid derivatives and their preparation | |
| JPS5212109A (en) | Process for preparation of alkylglycerylether | |
| JPS52122358A (en) | Novel methano-anthracene derivatives | |
| JPS5363347A (en) | Substd. benzoic acid amide and process for preparing them | |
| JPS532468A (en) | 2,2-bis(3,4-epoxy-5-oxotetrahydropyrane)-ethers and method of preparing the same | |
| JPS5414952A (en) | 1-halogenocarbonyltricyclo(4,3,1,12,5)undecane | |
| JPS52156876A (en) | Preparation of novel isoquinolone | |
| JPS5384937A (en) | Preparation of novel aromatic carboxylic acid amide derivatives | |
| JPS5738775A (en) | Quinazoline derivative | |
| JPS56161362A (en) | Anthranilic acid derivative | |
| JPS5283515A (en) | N-dimethyl-1- (l-(-)-alpha-hydroxy-omega-aminoalkanoyl) -xk-62-2 | |
| JPS5711975A (en) | Aminophenyltetrazole derivative and salt thereof | |
| JPS5368777A (en) | Preparation of phenyathridine | |
| JPS5350140A (en) | Novel derivatives of fortemycin b and process for preparation of the same | |
| JPS56167635A (en) | Alpha,beta-dihydropolyprenylcarboxylic acid and its derivative | |
| JPS5217442A (en) | Process for preparation of benzoylhydrazone derivatives | |
| JPS5436252A (en) | Novel propano-anthracene derivatives and their preparation | |
| JPS57131776A (en) | Prepatation of piperazine derivative | |
| JPS5242841A (en) | Process for preparation of thiolcarbamate derivatives | |
| JPS5414961A (en) | Novel 3-hydroxyazetidine-3-carboxylic derivative | |
| JPS52153961A (en) | 2-)n-alkyl, n-benzhydryl)-amino-2-imidazolines | |
| JPS53141217A (en) | New gamma-mercaptopropyl compound | |
| JPS5365882A (en) | 1,4-dihydro-4-oxonicotinic acids and process for preparation of the same |