JPS57185252A - Production of phenylacetonitrile derivative - Google Patents
Production of phenylacetonitrile derivativeInfo
- Publication number
- JPS57185252A JPS57185252A JP6914581A JP6914581A JPS57185252A JP S57185252 A JPS57185252 A JP S57185252A JP 6914581 A JP6914581 A JP 6914581A JP 6914581 A JP6914581 A JP 6914581A JP S57185252 A JPS57185252 A JP S57185252A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- alkyl
- halogen
- phenylacetonitrile derivative
- aralkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
PURPOSE: The reaction of a phenylacetonitrile derivative with a halogen compound is conducted in the presence of a specific compound to give readily high- purity titled compound used as a synthetic intermediate of drugs or dyes and a starting material of various chemicals in high yield.
CONSTITUTION: The reaction between a phenylacetonitrile derivative of formulaI(R is H, alkyl, aryl, aralkyl) and a halogen compound or R'X (R' is alkyl, alkenyl; X is halogen) is conducted in the presence of a compound of R1O(C2H4O)m(C3H6O)nR2(R1, R2 are H, alkyl, alkenyl, aryl, aralkyl; m is 4 or larger integer; n is 0 or 1 larger integer) such as polyethylene glycol (PEG)-400- dimethyl ether in an alkali hydroxide aqueous solution at 30W100°C for 2W8hr to give the objective compound of formula II.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6914581A JPS57185252A (en) | 1981-05-07 | 1981-05-07 | Production of phenylacetonitrile derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6914581A JPS57185252A (en) | 1981-05-07 | 1981-05-07 | Production of phenylacetonitrile derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57185252A true JPS57185252A (en) | 1982-11-15 |
JPH026344B2 JPH026344B2 (en) | 1990-02-08 |
Family
ID=13394188
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP6914581A Granted JPS57185252A (en) | 1981-05-07 | 1981-05-07 | Production of phenylacetonitrile derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57185252A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010018619A (en) * | 1997-12-17 | 2010-01-28 | Sanofi-Aventis Deutschland Gmbh | Method for alkylating benzyl cyanogen derivative under presence of trialkyl amine |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3886283A (en) * | 1971-05-31 | 1975-05-27 | Chinoin Gyogyszer Es Vegyeszet | Fungicidal carboxylic acid nitriles |
-
1981
- 1981-05-07 JP JP6914581A patent/JPS57185252A/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3886283A (en) * | 1971-05-31 | 1975-05-27 | Chinoin Gyogyszer Es Vegyeszet | Fungicidal carboxylic acid nitriles |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010018619A (en) * | 1997-12-17 | 2010-01-28 | Sanofi-Aventis Deutschland Gmbh | Method for alkylating benzyl cyanogen derivative under presence of trialkyl amine |
Also Published As
Publication number | Publication date |
---|---|
JPH026344B2 (en) | 1990-02-08 |
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