JPS57185252A - Production of phenylacetonitrile derivative - Google Patents

Production of phenylacetonitrile derivative

Info

Publication number
JPS57185252A
JPS57185252A JP6914581A JP6914581A JPS57185252A JP S57185252 A JPS57185252 A JP S57185252A JP 6914581 A JP6914581 A JP 6914581A JP 6914581 A JP6914581 A JP 6914581A JP S57185252 A JPS57185252 A JP S57185252A
Authority
JP
Japan
Prior art keywords
compound
alkyl
halogen
phenylacetonitrile derivative
aralkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6914581A
Other languages
Japanese (ja)
Other versions
JPH026344B2 (en
Inventor
Kazuaki Sugata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NIHON TOKUSHIYU KAGAKU KOGYO K
NIHON TOKUSHIYU KAGAKU KOGYO KK
NIPPON TOKUSHU KAGAKU KOGYO KK
Original Assignee
NIHON TOKUSHIYU KAGAKU KOGYO K
NIHON TOKUSHIYU KAGAKU KOGYO KK
NIPPON TOKUSHU KAGAKU KOGYO KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NIHON TOKUSHIYU KAGAKU KOGYO K, NIHON TOKUSHIYU KAGAKU KOGYO KK, NIPPON TOKUSHU KAGAKU KOGYO KK filed Critical NIHON TOKUSHIYU KAGAKU KOGYO K
Priority to JP6914581A priority Critical patent/JPS57185252A/en
Publication of JPS57185252A publication Critical patent/JPS57185252A/en
Publication of JPH026344B2 publication Critical patent/JPH026344B2/ja
Granted legal-status Critical Current

Links

Abstract

PURPOSE: The reaction of a phenylacetonitrile derivative with a halogen compound is conducted in the presence of a specific compound to give readily high- purity titled compound used as a synthetic intermediate of drugs or dyes and a starting material of various chemicals in high yield.
CONSTITUTION: The reaction between a phenylacetonitrile derivative of formulaI(R is H, alkyl, aryl, aralkyl) and a halogen compound or R'X (R' is alkyl, alkenyl; X is halogen) is conducted in the presence of a compound of R1O(C2H4O)m(C3H6O)nR2(R1, R2 are H, alkyl, alkenyl, aryl, aralkyl; m is 4 or larger integer; n is 0 or 1 larger integer) such as polyethylene glycol (PEG)-400- dimethyl ether in an alkali hydroxide aqueous solution at 30W100°C for 2W8hr to give the objective compound of formula II.
COPYRIGHT: (C)1982,JPO&Japio
JP6914581A 1981-05-07 1981-05-07 Production of phenylacetonitrile derivative Granted JPS57185252A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP6914581A JPS57185252A (en) 1981-05-07 1981-05-07 Production of phenylacetonitrile derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6914581A JPS57185252A (en) 1981-05-07 1981-05-07 Production of phenylacetonitrile derivative

Publications (2)

Publication Number Publication Date
JPS57185252A true JPS57185252A (en) 1982-11-15
JPH026344B2 JPH026344B2 (en) 1990-02-08

Family

ID=13394188

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6914581A Granted JPS57185252A (en) 1981-05-07 1981-05-07 Production of phenylacetonitrile derivative

Country Status (1)

Country Link
JP (1) JPS57185252A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010018619A (en) * 1997-12-17 2010-01-28 Sanofi-Aventis Deutschland Gmbh Method for alkylating benzyl cyanogen derivative under presence of trialkyl amine

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3886283A (en) * 1971-05-31 1975-05-27 Chinoin Gyogyszer Es Vegyeszet Fungicidal carboxylic acid nitriles

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3886283A (en) * 1971-05-31 1975-05-27 Chinoin Gyogyszer Es Vegyeszet Fungicidal carboxylic acid nitriles

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010018619A (en) * 1997-12-17 2010-01-28 Sanofi-Aventis Deutschland Gmbh Method for alkylating benzyl cyanogen derivative under presence of trialkyl amine

Also Published As

Publication number Publication date
JPH026344B2 (en) 1990-02-08

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