JPS57179146A - Amidine compound - Google Patents
Amidine compoundInfo
- Publication number
- JPS57179146A JPS57179146A JP6494281A JP6494281A JPS57179146A JP S57179146 A JPS57179146 A JP S57179146A JP 6494281 A JP6494281 A JP 6494281A JP 6494281 A JP6494281 A JP 6494281A JP S57179146 A JPS57179146 A JP S57179146A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- alkyl
- amidino
- reacted
- amidine compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 Amidine compound Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
- SEPJQQWQYNEMDL-UHFFFAOYSA-N (6-carbamimidoylnaphthalen-2-yl) benzoate Chemical compound C1=CC2=CC(C(=N)N)=CC=C2C=C1OC(=O)C1=CC=CC=C1 SEPJQQWQYNEMDL-UHFFFAOYSA-N 0.000 abstract 1
- ULKSSXOMKDEKPC-UHFFFAOYSA-N 6-hydroxynaphthalene-2-carboximidamide Chemical compound C1=C(O)C=CC2=CC(C(=N)N)=CC=C21 ULKSSXOMKDEKPC-UHFFFAOYSA-N 0.000 abstract 1
- 229910006124 SOCl2 Inorganic materials 0.000 abstract 1
- 150000001409 amidines Chemical class 0.000 abstract 1
- 230000003171 anti-complementary effect Effects 0.000 abstract 1
- 230000001475 anti-trypsic effect Effects 0.000 abstract 1
- 239000004019 antithrombin Substances 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- UHZYTMXLRWXGPK-UHFFFAOYSA-N phosphorus pentachloride Chemical compound ClP(Cl)(Cl)(Cl)Cl UHZYTMXLRWXGPK-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (20)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6494281A JPS57179146A (en) | 1981-04-28 | 1981-04-28 | Amidine compound |
AU75062/81A AU527371B2 (en) | 1980-09-16 | 1981-09-08 | Amidine |
US06/300,534 US4454338A (en) | 1980-09-16 | 1981-09-09 | Amidine compound |
CA000385570A CA1177488A (en) | 1980-09-16 | 1981-09-10 | Amidine compound, process for producing same and anti- complement agent comprising same |
ES505460A ES505460A0 (es) | 1980-09-16 | 1981-09-14 | Un procedimiento para preparar un derivado de amidina |
DK410681A DK155003C (da) | 1980-09-16 | 1981-09-15 | Analogifremgangsmaade til fremstilling af amidin-derivater eller farmaceutisk acceptable syreadditionssalte deraf |
FI812876A FI73975C (fi) | 1980-09-16 | 1981-09-15 | Foerfarande foer framstaellning av nya terapeutiskt anvaendbara amidinoderivat. |
DE8181107274T DE3174717D1 (en) | 1980-09-16 | 1981-09-15 | Novel amidine compounds, process for producing same and anti-complement agent comprising them |
GB8127837A GB2083818B (en) | 1980-09-16 | 1981-09-15 | Amidine compounds |
KR1019810003427A KR860000264B1 (ko) | 1980-09-16 | 1981-09-15 | 아미딘 화합물 및 그 염의 제조방법 |
CS816809A CS228534B2 (en) | 1980-09-16 | 1981-09-15 | Production method of amidine derivative |
SU813384251A SU1176832A3 (ru) | 1980-09-16 | 1981-09-15 | Способ получени амидиновых производных |
NO813138A NO153568C (no) | 1980-09-16 | 1981-09-15 | Analogifremgangsmaate for fremstilling av fysiologisk aktive amidinderivater. |
HU812665A HU185956B (en) | 1980-09-16 | 1981-09-15 | Process for producing new amidine derivatives and pharmaceutical compositions containing them as active agents |
EP81107274A EP0048433B1 (en) | 1980-09-16 | 1981-09-15 | Novel amidine compounds, process for producing same and anti-complement agent comprising them |
MX10156181U MX6922E (es) | 1980-09-16 | 1981-09-15 | Procedimiento para preparar compuestos de amidina |
AT81107274T ATE20051T1 (de) | 1980-09-16 | 1981-09-15 | Amidinderivate, verfahren zu ihrer herstellung und diese enthaltende antikomplement-mittel. |
PH26206A PH18109A (en) | 1980-09-16 | 1981-09-15 | Novel amidine compounds and anti-complement pharmaceutical composition comprising same |
DD81233339A DD201779A5 (de) | 1980-09-16 | 1981-09-16 | Verfahren zur herstellung neuer amidinverbindungen |
US06/572,269 US4532255A (en) | 1980-09-16 | 1984-01-20 | Amidine compounds and anticomplement agent comprising same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6494281A JPS57179146A (en) | 1981-04-28 | 1981-04-28 | Amidine compound |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57179146A true JPS57179146A (en) | 1982-11-04 |
JPH037663B2 JPH037663B2 (enrdf_load_stackoverflow) | 1991-02-04 |
Family
ID=13272585
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP6494281A Granted JPS57179146A (en) | 1980-09-16 | 1981-04-28 | Amidine compound |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57179146A (enrdf_load_stackoverflow) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59139357A (ja) * | 1983-01-28 | 1984-08-10 | Torii Yakuhin Kk | アミジン誘導体 |
WO1986000893A1 (en) * | 1984-07-25 | 1986-02-13 | Torii & Co., Ltd. | Novel amidine compounds |
WO1996020920A1 (fr) * | 1995-01-05 | 1996-07-11 | Torii Pharmaceutical Co., Ltd. | Derive d'ester d'amidinonaphtyle |
WO1996020917A1 (fr) * | 1995-01-05 | 1996-07-11 | Torii Pharmaceutical Co., Ltd. | Derives d'ester d'amidinonaphtyle substitues |
WO2001094299A1 (fr) * | 2000-06-08 | 2001-12-13 | Shizuoka Coffein Co., Ltd. | Derives de benzene |
JP2012087099A (ja) * | 2010-10-21 | 2012-05-10 | Katsura Chemical Co Ltd | ナファモスタットメシル酸塩の晶析方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5283538A (en) * | 1976-01-01 | 1977-07-12 | Kyowa Hakko Kogyo Co Ltd | 6-amidinonaphthalene derivatives |
JPS565451A (en) * | 1979-06-27 | 1981-01-20 | Kowa Co | Acylamidinophenol derivative |
-
1981
- 1981-04-28 JP JP6494281A patent/JPS57179146A/ja active Granted
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5283538A (en) * | 1976-01-01 | 1977-07-12 | Kyowa Hakko Kogyo Co Ltd | 6-amidinonaphthalene derivatives |
JPS565451A (en) * | 1979-06-27 | 1981-01-20 | Kowa Co | Acylamidinophenol derivative |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59139357A (ja) * | 1983-01-28 | 1984-08-10 | Torii Yakuhin Kk | アミジン誘導体 |
WO1986000893A1 (en) * | 1984-07-25 | 1986-02-13 | Torii & Co., Ltd. | Novel amidine compounds |
JPS6133173A (ja) * | 1984-07-25 | 1986-02-17 | Torii Yakuhin Kk | アミジン化合物 |
WO1996020920A1 (fr) * | 1995-01-05 | 1996-07-11 | Torii Pharmaceutical Co., Ltd. | Derive d'ester d'amidinonaphtyle |
WO1996020917A1 (fr) * | 1995-01-05 | 1996-07-11 | Torii Pharmaceutical Co., Ltd. | Derives d'ester d'amidinonaphtyle substitues |
AU686104B2 (en) * | 1995-01-05 | 1998-02-05 | Torii Pharmaceutical Co., Ltd. | Substituted amidinonaphthyl ester derivatives |
US5885990A (en) * | 1995-01-05 | 1999-03-23 | Torii Pharmaceutical Co., Ltd. | Substituted amidinonaphthyl ester derivative |
WO2001094299A1 (fr) * | 2000-06-08 | 2001-12-13 | Shizuoka Coffein Co., Ltd. | Derives de benzene |
JP2012087099A (ja) * | 2010-10-21 | 2012-05-10 | Katsura Chemical Co Ltd | ナファモスタットメシル酸塩の晶析方法 |
Also Published As
Publication number | Publication date |
---|---|
JPH037663B2 (enrdf_load_stackoverflow) | 1991-02-04 |
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