JPS57179141A - Bicyclic compound and its preparation - Google Patents
Bicyclic compound and its preparationInfo
- Publication number
- JPS57179141A JPS57179141A JP56064371A JP6437181A JPS57179141A JP S57179141 A JPS57179141 A JP S57179141A JP 56064371 A JP56064371 A JP 56064371A JP 6437181 A JP6437181 A JP 6437181A JP S57179141 A JPS57179141 A JP S57179141A
- Authority
- JP
- Japan
- Prior art keywords
- compound shown
- formula
- lower alkyl
- formulai
- enzyme capable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 Bicyclic compound Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 7
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- IVLXQGJVBGMLRR-UHFFFAOYSA-N 2-aminoacetic acid;hydron;chloride Chemical compound Cl.NCC(O)=O IVLXQGJVBGMLRR-UHFFFAOYSA-N 0.000 abstract 1
- 108010064733 Angiotensins Proteins 0.000 abstract 1
- 102000015427 Angiotensins Human genes 0.000 abstract 1
- 101800004538 Bradykinin Proteins 0.000 abstract 1
- QXZGBUJJYSLZLT-UHFFFAOYSA-N H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH Natural products NC(N)=NCCCC(N)C(=O)N1CCCC1C(=O)N1C(C(=O)NCC(=O)NC(CC=2C=CC=CC=2)C(=O)NC(CO)C(=O)N2C(CCC2)C(=O)NC(CC=2C=CC=CC=2)C(=O)NC(CCCN=C(N)N)C(O)=O)CCC1 QXZGBUJJYSLZLT-UHFFFAOYSA-N 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 102100035792 Kininogen-1 Human genes 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- QXZGBUJJYSLZLT-FDISYFBBSA-N bradykinin Chemical compound NC(=N)NCCC[C@H](N)C(=O)N1CCC[C@H]1C(=O)N1[C@H](C(=O)NCC(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CO)C(=O)N2[C@@H](CCC2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)CCC1 QXZGBUJJYSLZLT-FDISYFBBSA-N 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 229960001269 glycine hydrochloride Drugs 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (31)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56064371A JPS57179141A (en) | 1981-04-28 | 1981-04-28 | Bicyclic compound and its preparation |
AU76521/81A AU543804B2 (en) | 1980-10-31 | 1981-10-16 | Amides having bicyclic substituents on nitrogen |
US06/312,639 US4822818A (en) | 1980-10-31 | 1981-10-19 | Bicycle compounds, their production and use |
GB8131719A GB2086393B (en) | 1980-10-31 | 1981-10-21 | Bicyclic compounds |
IE2471/81A IE51918B1 (en) | 1980-10-31 | 1981-10-21 | Bicyclic compounds their production and use |
DE8181304940T DE3165862D1 (en) | 1980-10-31 | 1981-10-21 | Bicyclic compounds, their production and use |
EP81304940A EP0051391B1 (en) | 1980-10-31 | 1981-10-21 | Bicyclic compounds, their production and use |
AT81304940T ATE9220T1 (de) | 1980-10-31 | 1981-10-21 | Bizyklische verbindungen, ihre herstellung und verwendung. |
PH26409A PH18357A (en) | 1980-10-31 | 1981-10-28 | Bicyclic compounds,their production and use |
FI813383A FI73698C (fi) | 1980-10-31 | 1981-10-28 | Foerfarande foer framstaellning av nya farmaceutiskt verksamma n-indanylglycinderivat. |
MX7586A MX154997A (es) | 1980-10-31 | 1981-10-29 | Procedimiento para preparar compuestos biciclicos |
KR1019810004142A KR880000890B1 (ko) | 1980-10-31 | 1981-10-29 | 두고리 화합물의 제조방법 |
HU813176A HU183652B (en) | 1980-10-31 | 1981-10-29 | Process for preparing bicyclic compounds |
GR66380A GR75368B (enrdf_load_stackoverflow) | 1980-10-31 | 1981-10-29 | |
CA000389042A CA1287444C (en) | 1980-10-31 | 1981-10-29 | Bicyclic compounds, their production and use |
NO813662A NO155133C (no) | 1980-10-31 | 1981-10-29 | Analogifremgangsmaate for fremstilling av terapeutisk virksomme dicykliske forbindelser. |
DK478181A DK164917C (da) | 1980-10-31 | 1981-10-29 | Analogifremgangsmaade til fremstilling af bicyklisk substituerede dipeptidderivater og deres farmaceutisk acceptable salte |
ES506714A ES506714A0 (es) | 1980-10-31 | 1981-10-30 | Un procedimiento para obtener compuestos biciclicos |
PT73912A PT73912B (en) | 1980-10-31 | 1981-10-30 | Bicyclic compounds their production and use |
IL64168A IL64168A0 (en) | 1980-10-31 | 1981-10-30 | Carboxamidoindan and naphthalene derivatives,their production and pharmaceutical compositions containing them |
NZ198826A NZ198826A (en) | 1980-10-31 | 1981-10-30 | Bicyclic compounds and pharmaceutical compositions |
ES515269A ES515269A0 (es) | 1980-10-31 | 1982-08-26 | Un procedimiento para obtener compuestos biciclicos derivados del indano o benzociclohexano. |
US06/494,061 US4474692A (en) | 1980-10-31 | 1983-05-12 | L-Alanyl-N-(indan-2-yl)glycine, its esters and salts thereof |
ES524148A ES8504671A1 (es) | 1980-10-31 | 1983-07-15 | Un procedimiento para obtener compuestos biciclicos derivados del indano o benzociclohexano |
PH29829A PH21390A (en) | 1980-10-31 | 1983-10-12 | Process for producing l-alanyl-n-(indian-2-yl)glycine derivatives |
CA000468185A CA1287446C (en) | 1980-10-31 | 1984-11-19 | Bicyclic compounds, their production and use |
MY500/85A MY8500500A (en) | 1980-10-31 | 1985-12-30 | Bicyclic compounds their production and use |
NO862859A NO157103C (no) | 1980-10-31 | 1986-07-15 | Analogifremgangsmÿte for fremstilling av terapeutisk virksomme dicykliske forbindelser. |
KR1019860009085A KR880001007B1 (ko) | 1980-10-31 | 1986-10-29 | 비사이클릭 화합물의 제조 방법 |
HK198/87A HK19887A (en) | 1980-10-31 | 1987-03-05 | Bicyclic compounds their production and use |
US07/302,940 US5098892A (en) | 1980-10-31 | 1989-01-30 | Process for preparation of bicyclic compounds |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56064371A JPS57179141A (en) | 1981-04-28 | 1981-04-28 | Bicyclic compound and its preparation |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3000087A Division JPS632963A (ja) | 1987-02-12 | 1987-02-12 | 二環式化合物の製造法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57179141A true JPS57179141A (en) | 1982-11-04 |
JPH0223538B2 JPH0223538B2 (enrdf_load_stackoverflow) | 1990-05-24 |
Family
ID=13256352
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56064371A Granted JPS57179141A (en) | 1980-10-31 | 1981-04-28 | Bicyclic compound and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57179141A (enrdf_load_stackoverflow) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6251650A (ja) * | 1985-08-27 | 1987-03-06 | チバ・ガイギ−・アクチエンゲゼルシヤフト | ヒドロピリジン誘導体、その製造法及び向知性薬 |
-
1981
- 1981-04-28 JP JP56064371A patent/JPS57179141A/ja active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6251650A (ja) * | 1985-08-27 | 1987-03-06 | チバ・ガイギ−・アクチエンゲゼルシヤフト | ヒドロピリジン誘導体、その製造法及び向知性薬 |
Also Published As
Publication number | Publication date |
---|---|
JPH0223538B2 (enrdf_load_stackoverflow) | 1990-05-24 |
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