JPS57171988A - Novel fluoroprostacyclins - Google Patents

Novel fluoroprostacyclins

Info

Publication number
JPS57171988A
JPS57171988A JP57035978A JP3597882A JPS57171988A JP S57171988 A JPS57171988 A JP S57171988A JP 57035978 A JP57035978 A JP 57035978A JP 3597882 A JP3597882 A JP 3597882A JP S57171988 A JPS57171988 A JP S57171988A
Authority
JP
Japan
Prior art keywords
fluoroprostacyclins
novel
novel fluoroprostacyclins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP57035978A
Other languages
English (en)
Japanese (ja)
Inventor
Uiriamu Horando Jiyooji
Maaku Hansu
Roozen Perii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of JPS57171988A publication Critical patent/JPS57171988A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP57035978A 1981-03-11 1982-03-09 Novel fluoroprostacyclins Pending JPS57171988A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24281881A 1981-03-11 1981-03-11

Publications (1)

Publication Number Publication Date
JPS57171988A true JPS57171988A (en) 1982-10-22

Family

ID=22916307

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57035978A Pending JPS57171988A (en) 1981-03-11 1982-03-09 Novel fluoroprostacyclins

Country Status (5)

Country Link
JP (1) JPS57171988A (enExample)
KR (1) KR860002049B1 (enExample)
BE (1) BE892434A (enExample)
GR (1) GR76075B (enExample)
ZA (1) ZA821449B (enExample)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57165382A (en) * 1981-04-06 1982-10-12 Teijin Ltd Fluoro-pgi2 compound and its preparation
JPS57200378A (en) * 1981-06-02 1982-12-08 Teijin Ltd Halogenated pgi2 and its preparation
JPS58150583A (ja) * 1982-03-04 1983-09-07 Teijin Ltd 新規なハロゲン化プロスタサイクリン類、それらの製造法およびそれらを活性成分とする薬学的組成物
US4472428A (en) * 1980-12-09 1984-09-18 Teijin Limited Halogenated prostacyclins pharmaceutical use thereof and hydroxy intermediates therefore
WO1984004917A1 (fr) * 1983-06-10 1984-12-20 Asahi Glass Co Ltd 7-fluoroprostaglandines et leur procede de preparation
US5538995A (en) * 1994-02-17 1996-07-23 Asahi Glass Company Ltd. Difluoroprostacyclins

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5799580A (en) * 1980-10-27 1982-06-21 Chinoin Gyogyszer Es Vegyeszet 7-substituted pgi2 derivative and manufacture
JPS57165382A (en) * 1981-04-06 1982-10-12 Teijin Ltd Fluoro-pgi2 compound and its preparation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5799580A (en) * 1980-10-27 1982-06-21 Chinoin Gyogyszer Es Vegyeszet 7-substituted pgi2 derivative and manufacture
JPS57165382A (en) * 1981-04-06 1982-10-12 Teijin Ltd Fluoro-pgi2 compound and its preparation

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4472428A (en) * 1980-12-09 1984-09-18 Teijin Limited Halogenated prostacyclins pharmaceutical use thereof and hydroxy intermediates therefore
JPS57165382A (en) * 1981-04-06 1982-10-12 Teijin Ltd Fluoro-pgi2 compound and its preparation
JPS57200378A (en) * 1981-06-02 1982-12-08 Teijin Ltd Halogenated pgi2 and its preparation
JPS58150583A (ja) * 1982-03-04 1983-09-07 Teijin Ltd 新規なハロゲン化プロスタサイクリン類、それらの製造法およびそれらを活性成分とする薬学的組成物
WO1984004917A1 (fr) * 1983-06-10 1984-12-20 Asahi Glass Co Ltd 7-fluoroprostaglandines et leur procede de preparation
US5538995A (en) * 1994-02-17 1996-07-23 Asahi Glass Company Ltd. Difluoroprostacyclins

Also Published As

Publication number Publication date
GR76075B (enExample) 1984-08-03
KR830009079A (ko) 1983-12-17
KR860002049B1 (ko) 1986-11-20
BE892434A (fr) 1982-09-10
ZA821449B (en) 1983-01-26

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