JPS57171915A - Manufacture of lipid membrane structure - Google Patents
Manufacture of lipid membrane structureInfo
- Publication number
- JPS57171915A JPS57171915A JP56206324A JP20632481A JPS57171915A JP S57171915 A JPS57171915 A JP S57171915A JP 56206324 A JP56206324 A JP 56206324A JP 20632481 A JP20632481 A JP 20632481A JP S57171915 A JPS57171915 A JP S57171915A
- Authority
- JP
- Japan
- Prior art keywords
- lipid membrane
- manufacture
- membrane structure
- solvent system
- membrane structures
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000002632 lipids Chemical class 0.000 title abstract 3
- 239000012528 membrane Substances 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- 239000011149 active material Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000002502 liposome Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/06—Making microcapsules or microballoons by phase separation
- B01J13/12—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution
- B01J13/125—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution by evaporation of the solvent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Fats And Perfumes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21918680A | 1980-12-22 | 1980-12-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57171915A true JPS57171915A (en) | 1982-10-22 |
Family
ID=22818233
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56206324A Pending JPS57171915A (en) | 1980-12-22 | 1981-12-22 | Manufacture of lipid membrane structure |
Country Status (17)
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59222410A (ja) * | 1983-06-01 | 1984-12-14 | Terumo Corp | 薬物保持リポソ−ム製剤 |
JPS6012127A (ja) * | 1983-06-30 | 1985-01-22 | Dai Ichi Seiyaku Co Ltd | リポソ−ムの製法 |
JPH02149336A (ja) * | 1988-06-30 | 1990-06-07 | Centre Natl Rech Scient <Cnrs> | サブミクロン大リポソームの形態の両親媒性脂質の分散性コロイド系の調製方法 |
JPH03207443A (ja) * | 1989-10-12 | 1991-09-10 | L'oreal Sa | 脂質ベシクル水性分散液の製法及び該分散液に基づく組成物 |
JP2005538967A (ja) * | 2002-06-28 | 2005-12-22 | プロティバ バイオセラピューティクス リミテッド | リポソーム製造方法および装置 |
JP2007533747A (ja) * | 2004-04-20 | 2007-11-22 | ダウ・コーニング・コーポレイション | 活性剤を含むシリコーン小胞 |
JP2007533452A (ja) * | 2004-04-20 | 2007-11-22 | ダウ・コーニング・コーポレイション | シリコーンベシクル |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0088046B1 (de) * | 1982-02-17 | 1987-12-09 | Ciba-Geigy Ag | Lipide in wässriger Phase |
FR2543018B1 (fr) * | 1983-03-22 | 1985-07-26 | Oreal | Procede de preparation de vesicules lipidiques par vaporisation de solvants |
JPS607932A (ja) * | 1983-06-29 | 1985-01-16 | Dai Ichi Seiyaku Co Ltd | リポソーム懸濁液およびその製法 |
JPS6072831A (ja) * | 1983-09-29 | 1985-04-24 | Kao Corp | ベシクル用組成物 |
US4728575A (en) * | 1984-04-27 | 1988-03-01 | Vestar, Inc. | Contrast agents for NMR imaging |
US4707453A (en) * | 1985-04-05 | 1987-11-17 | Becton Dickinson And Company | Vesicle including a metal marker for use in an assay |
US4698263A (en) * | 1985-05-23 | 1987-10-06 | Becton Dickinson And Company | Sac having a marker linked thereto |
US5041278A (en) * | 1985-10-15 | 1991-08-20 | The Liposome Company, Inc. | Alpha tocopherol-based vesicles |
US4861580A (en) * | 1985-10-15 | 1989-08-29 | The Liposome Company, Inc. | Composition using salt form of organic acid derivative of alpha-tocopheral |
US4812314A (en) * | 1986-02-24 | 1989-03-14 | Yissum Research & Dev. Co. Of The Hebrew Univ. Of Jerusalem And Hadassah Medical Organization | Lipid replacement therapy |
DE3812816A1 (de) * | 1988-04-16 | 1989-11-02 | Lawaczeck Ruediger Dipl Phys P | Verfahren zur solubilisierung von liposomen und/oder biologischer membranen sowie deren verwendung |
WO1989011335A1 (en) * | 1988-05-17 | 1989-11-30 | Liposome Technology, Inc. | Preparation of uniform-size liposomes and other lipid structures |
US4994213A (en) * | 1988-05-17 | 1991-02-19 | Liposome Technology, Inc. | Method of preparing lipid structures |
US5000887A (en) * | 1988-05-17 | 1991-03-19 | Liposome Technology, Inc. | Preparation of uniform-size liposomes |
FR2648056A1 (fr) * | 1989-06-13 | 1990-12-14 | Ire Celltarg Sa | Procede de preparation de microparticules lipidiques d'aspect microcristallin |
FR2653015B1 (fr) * | 1989-10-12 | 1993-10-29 | Oreal | Composition cosmetique ou pharmaceutique pour application topique contenant au moins un derive retinouide et au moins un derive de pyrimidine, son utilisation comme medicament et procede de traitement correspondant. |
GB9108043D0 (en) * | 1991-04-16 | 1991-06-05 | Phares Pharm Res Nv | Method for the formation of liposomes and compositions for use therein |
JPH06247842A (ja) * | 1993-02-23 | 1994-09-06 | Green Cross Corp:The | リポソーム組成物の製造方法 |
US6235308B1 (en) | 1994-06-10 | 2001-05-22 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Method of treating hypertension |
US5622715A (en) * | 1994-06-10 | 1997-04-22 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Method of improving renal function |
WO1996040061A1 (en) * | 1995-06-07 | 1996-12-19 | Nexstar Pharmaceuticals, Inc. | Method for encapsulating pharmaceutical materials |
DE19951509A1 (de) * | 1999-10-26 | 2001-10-31 | Biotul Ag I K | Substratgestützte Lipiddoppelschichten |
US9005654B2 (en) | 2005-07-27 | 2015-04-14 | Protiva Biotherapeutics, Inc. | Systems and methods for manufacturing liposomes |
CN118647600A (zh) | 2021-12-16 | 2024-09-13 | 爱康泰生治疗公司 | 用于脂质纳米颗粒制剂的脂质 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2237545A1 (de) * | 1972-07-31 | 1974-02-14 | Basf Ag | Verfahren zur herstellung von mikrokapseln |
CH624011A5 (US06444660-20020903-C00009.png) * | 1977-08-05 | 1981-07-15 | Battelle Memorial Institute | |
US4235871A (en) * | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
-
1981
- 1981-12-18 GR GR66833A patent/GR77320B/el unknown
- 1981-12-21 DE DE8181306002T patent/DE3165290D1/de not_active Expired
- 1981-12-21 GB GB8138369A patent/GB2089681B/en not_active Expired
- 1981-12-21 ZA ZA818801A patent/ZA818801B/xx unknown
- 1981-12-21 AT AT81306002T patent/ATE8743T1/de not_active IP Right Cessation
- 1981-12-21 ES ES508174A patent/ES8300499A1/es not_active Expired
- 1981-12-21 EP EP81306002A patent/EP0055576B1/en not_active Expired
- 1981-12-21 CA CA000392869A patent/CA1154674A/en not_active Expired
- 1981-12-21 FI FI814113A patent/FI814113L/fi not_active Application Discontinuation
- 1981-12-22 DK DK572781A patent/DK572781A/da not_active Application Discontinuation
- 1981-12-22 IE IE3028/81A patent/IE52258B1/en unknown
- 1981-12-22 NZ NZ199367A patent/NZ199367A/en unknown
- 1981-12-22 NO NO814410A patent/NO814410L/no unknown
- 1981-12-22 PH PH26669A patent/PH17923A/en unknown
- 1981-12-22 AU AU78787/81A patent/AU553643B2/en not_active Ceased
- 1981-12-22 JP JP56206324A patent/JPS57171915A/ja active Pending
- 1981-12-22 MA MA19563A patent/MA19358A1/fr unknown
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59222410A (ja) * | 1983-06-01 | 1984-12-14 | Terumo Corp | 薬物保持リポソ−ム製剤 |
JPS6012127A (ja) * | 1983-06-30 | 1985-01-22 | Dai Ichi Seiyaku Co Ltd | リポソ−ムの製法 |
JPH0457375B2 (US06444660-20020903-C00009.png) * | 1983-06-30 | 1992-09-11 | Daiichi Seiyaku Co | |
JPH02149336A (ja) * | 1988-06-30 | 1990-06-07 | Centre Natl Rech Scient <Cnrs> | サブミクロン大リポソームの形態の両親媒性脂質の分散性コロイド系の調製方法 |
JPH03207443A (ja) * | 1989-10-12 | 1991-09-10 | L'oreal Sa | 脂質ベシクル水性分散液の製法及び該分散液に基づく組成物 |
JP2005538967A (ja) * | 2002-06-28 | 2005-12-22 | プロティバ バイオセラピューティクス リミテッド | リポソーム製造方法および装置 |
JP4722481B2 (ja) * | 2002-06-28 | 2011-07-13 | プロティバ バイオセラピューティクス リミテッド | リポソーム製造方法および装置 |
JP2016172778A (ja) * | 2002-06-28 | 2016-09-29 | プロティバ バイオセラピューティクス, インコーポレイテッド | リポソーム製造方法および装置 |
US11298320B2 (en) | 2002-06-28 | 2022-04-12 | Arbutus Biopharma Corporation | Liposomal apparatus and manufacturing methods |
US11318098B2 (en) | 2002-06-28 | 2022-05-03 | Arbutus Biopharma Corporation | Liposomal apparatus and manufacturing methods |
JP2007533747A (ja) * | 2004-04-20 | 2007-11-22 | ダウ・コーニング・コーポレイション | 活性剤を含むシリコーン小胞 |
JP2007533452A (ja) * | 2004-04-20 | 2007-11-22 | ダウ・コーニング・コーポレイション | シリコーンベシクル |
Also Published As
Publication number | Publication date |
---|---|
EP0055576A1 (en) | 1982-07-07 |
ES508174A0 (es) | 1982-11-01 |
GB2089681B (en) | 1984-08-22 |
DE3165290D1 (en) | 1984-09-06 |
GB2089681A (en) | 1982-06-30 |
ATE8743T1 (de) | 1984-08-15 |
IE52258B1 (en) | 1987-08-19 |
PH17923A (en) | 1985-01-31 |
FI814113L (fi) | 1982-06-23 |
ZA818801B (en) | 1982-11-24 |
CA1154674A (en) | 1983-10-04 |
MA19358A1 (fr) | 1982-07-01 |
DK572781A (da) | 1982-06-23 |
GR77320B (US06444660-20020903-C00009.png) | 1984-09-11 |
AU7878781A (en) | 1982-07-01 |
NZ199367A (en) | 1985-05-31 |
EP0055576B1 (en) | 1984-08-01 |
NO814410L (no) | 1982-06-23 |
IE813028L (en) | 1982-06-22 |
AU553643B2 (en) | 1986-07-24 |
ES8300499A1 (es) | 1982-11-01 |
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