JPS57163398A - Condurango glycoside, its preparation and antitumor agent containing the same - Google Patents

Condurango glycoside, its preparation and antitumor agent containing the same

Info

Publication number
JPS57163398A
JPS57163398A JP56047553A JP4755381A JPS57163398A JP S57163398 A JPS57163398 A JP S57163398A JP 56047553 A JP56047553 A JP 56047553A JP 4755381 A JP4755381 A JP 4755381A JP S57163398 A JPS57163398 A JP S57163398A
Authority
JP
Japan
Prior art keywords
preparation
carbon tetrachloride
condurango
antitumor agent
chlorinated hydrocarbon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56047553A
Other languages
Japanese (ja)
Other versions
JPS6354000B2 (en
Inventor
Hiroshi Mihashi
Denichi Mizuno
Koji Hayashi
Shigeru Abe
Muneaki Takase
Toshiharu Narita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zenyaku Kogyo KK
Original Assignee
Zenyaku Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zenyaku Kogyo KK filed Critical Zenyaku Kogyo KK
Priority to JP56047553A priority Critical patent/JPS57163398A/en
Priority to AU82752/82A priority patent/AU8275282A/en
Priority to PCT/JP1982/000088 priority patent/WO1982003396A1/en
Publication of JPS57163398A publication Critical patent/JPS57163398A/en
Publication of JPS6354000B2 publication Critical patent/JPS6354000B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:Condurango glycoside E01 of the formula having following properties: white amorphous solid; melting point: 164W174°C; specific rotatory power: [α]D20=+69.8° (c=0.49 in methanol); elementary analyses in %: C 59.11, H 7.76.
USE: Antitumor agent.
PREPARATION: Condurango in Asclepiadaceae, preferably finely cut barks, is extracted with a lower alcohol such as methanol and a chlorinated hydrocarbon other than carbon tetrachloride such as chloroform and the extract is subjected to an open column, then eluted with a chlorinated hydrocarbon other than carbon tetrachloride. Then, the fraction eluted with a mixture of a lower alcohol and a chlorinated hydrocarbon other than carbon tetrachloride is isolated by means of high-speed liquid chromatography.
COPYRIGHT: (C)1982,JPO&Japio
JP56047553A 1981-03-31 1981-03-31 Condurango glycoside, its preparation and antitumor agent containing the same Granted JPS57163398A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP56047553A JPS57163398A (en) 1981-03-31 1981-03-31 Condurango glycoside, its preparation and antitumor agent containing the same
AU82752/82A AU8275282A (en) 1981-03-31 1982-03-30 Novel cundurango glycoside compounds, process for their preparation, their use as anthumor agent, and composition containing them
PCT/JP1982/000088 WO1982003396A1 (en) 1981-03-31 1982-03-30 Novel cundurango glycoside compounds,process for their preparation,their use as antitumor agent,and composition containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56047553A JPS57163398A (en) 1981-03-31 1981-03-31 Condurango glycoside, its preparation and antitumor agent containing the same

Publications (2)

Publication Number Publication Date
JPS57163398A true JPS57163398A (en) 1982-10-07
JPS6354000B2 JPS6354000B2 (en) 1988-10-26

Family

ID=12778354

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56047553A Granted JPS57163398A (en) 1981-03-31 1981-03-31 Condurango glycoside, its preparation and antitumor agent containing the same

Country Status (1)

Country Link
JP (1) JPS57163398A (en)

Also Published As

Publication number Publication date
JPS6354000B2 (en) 1988-10-26

Similar Documents

Publication Publication Date Title
JPS5414454A (en) Composition of poly-4-methyl-pentene-1
JPS57163398A (en) Condurango glycoside, its preparation and antitumor agent containing the same
Sheu et al. Chemical constituents of a Formosan soft coral Sinularia sp.
JPS55136257A (en) Purification of alpha-l-aspartyl-l-phenylalanine lower alkyl ester
JPS57120589A (en) 5-methoxy and 5-lower alkanoyloxy derivative, its preparation and acaricide and parasiticide
Chaudhuri A labdane diterpenoid sterol from Lagerstroemia lancasteri
JPS54101412A (en) Preparation of vitamin p
JPS543019A (en) Preparation of 4-nitrosodiphenylamine hydrochliride
JPS5742643A (en) 6,10,14,18-tetramethyl-5,9,13,17-nonadecatetraene-2-ol
JPS5620597A (en) Novel physiologically active substance
JPS52102217A (en) Purification of glycidyl esters
JPS5754181A (en) Biflavonoid compound and its preparation
González et al. Distribution of sesquiterpene lactones in Cheirolophus from the Canary Islands
JPS547405A (en) Production of fuel oil composition
JPS5282895A (en) Fire-resistant mixture
EP0163356A3 (en) Process for the preparation of stable mixtures of coal and oil
JPS6440459A (en) Novel tryptophan derivative and glycoside thereof
JPS537610A (en) Preparation of nonallergic lanolin
JPS56108719A (en) Novel antibiotic antlermicin b and c, and their preparation
JPS5579322A (en) Antitumor agent comprising dc-11
JPS55167300A (en) Cynanchogenin glycoside and its preparation
JPS642518A (en) Culture net for laver
JPS53111001A (en) Separation of mixture of hydrocarbons
JPS5522622A (en) Preparation of epoxyterpene
JPS53121713A (en) Separation of butanediol