JPS57163398A - Condurango glycoside, its preparation and antitumor agent containing the same - Google Patents
Condurango glycoside, its preparation and antitumor agent containing the sameInfo
- Publication number
- JPS57163398A JPS57163398A JP56047553A JP4755381A JPS57163398A JP S57163398 A JPS57163398 A JP S57163398A JP 56047553 A JP56047553 A JP 56047553A JP 4755381 A JP4755381 A JP 4755381A JP S57163398 A JPS57163398 A JP S57163398A
- Authority
- JP
- Japan
- Prior art keywords
- preparation
- carbon tetrachloride
- condurango
- antitumor agent
- chlorinated hydrocarbon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:Condurango glycoside E01 of the formula having following properties: white amorphous solid; melting point: 164W174°C; specific rotatory power: [α]D20=+69.8° (c=0.49 in methanol); elementary analyses in %: C 59.11, H 7.76.
USE: Antitumor agent.
PREPARATION: Condurango in Asclepiadaceae, preferably finely cut barks, is extracted with a lower alcohol such as methanol and a chlorinated hydrocarbon other than carbon tetrachloride such as chloroform and the extract is subjected to an open column, then eluted with a chlorinated hydrocarbon other than carbon tetrachloride. Then, the fraction eluted with a mixture of a lower alcohol and a chlorinated hydrocarbon other than carbon tetrachloride is isolated by means of high-speed liquid chromatography.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56047553A JPS57163398A (en) | 1981-03-31 | 1981-03-31 | Condurango glycoside, its preparation and antitumor agent containing the same |
AU82752/82A AU8275282A (en) | 1981-03-31 | 1982-03-30 | Novel cundurango glycoside compounds, process for their preparation, their use as anthumor agent, and composition containing them |
PCT/JP1982/000088 WO1982003396A1 (en) | 1981-03-31 | 1982-03-30 | Novel cundurango glycoside compounds,process for their preparation,their use as antitumor agent,and composition containing them |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56047553A JPS57163398A (en) | 1981-03-31 | 1981-03-31 | Condurango glycoside, its preparation and antitumor agent containing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57163398A true JPS57163398A (en) | 1982-10-07 |
JPS6354000B2 JPS6354000B2 (en) | 1988-10-26 |
Family
ID=12778354
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56047553A Granted JPS57163398A (en) | 1981-03-31 | 1981-03-31 | Condurango glycoside, its preparation and antitumor agent containing the same |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57163398A (en) |
-
1981
- 1981-03-31 JP JP56047553A patent/JPS57163398A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6354000B2 (en) | 1988-10-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS5414454A (en) | Composition of poly-4-methyl-pentene-1 | |
JPS57163398A (en) | Condurango glycoside, its preparation and antitumor agent containing the same | |
Sheu et al. | Chemical constituents of a Formosan soft coral Sinularia sp. | |
JPS55136257A (en) | Purification of alpha-l-aspartyl-l-phenylalanine lower alkyl ester | |
JPS57120589A (en) | 5-methoxy and 5-lower alkanoyloxy derivative, its preparation and acaricide and parasiticide | |
Chaudhuri | A labdane diterpenoid sterol from Lagerstroemia lancasteri | |
JPS54101412A (en) | Preparation of vitamin p | |
JPS543019A (en) | Preparation of 4-nitrosodiphenylamine hydrochliride | |
JPS5742643A (en) | 6,10,14,18-tetramethyl-5,9,13,17-nonadecatetraene-2-ol | |
JPS5620597A (en) | Novel physiologically active substance | |
JPS52102217A (en) | Purification of glycidyl esters | |
JPS5754181A (en) | Biflavonoid compound and its preparation | |
González et al. | Distribution of sesquiterpene lactones in Cheirolophus from the Canary Islands | |
JPS547405A (en) | Production of fuel oil composition | |
JPS5282895A (en) | Fire-resistant mixture | |
EP0163356A3 (en) | Process for the preparation of stable mixtures of coal and oil | |
JPS6440459A (en) | Novel tryptophan derivative and glycoside thereof | |
JPS537610A (en) | Preparation of nonallergic lanolin | |
JPS56108719A (en) | Novel antibiotic antlermicin b and c, and their preparation | |
JPS5579322A (en) | Antitumor agent comprising dc-11 | |
JPS55167300A (en) | Cynanchogenin glycoside and its preparation | |
JPS642518A (en) | Culture net for laver | |
JPS53111001A (en) | Separation of mixture of hydrocarbons | |
JPS5522622A (en) | Preparation of epoxyterpene | |
JPS53121713A (en) | Separation of butanediol |