JPS57163383A - Neplanocin a derivative - Google Patents
Neplanocin a derivativeInfo
- Publication number
- JPS57163383A JPS57163383A JP17640180A JP17640180A JPS57163383A JP S57163383 A JPS57163383 A JP S57163383A JP 17640180 A JP17640180 A JP 17640180A JP 17640180 A JP17640180 A JP 17640180A JP S57163383 A JPS57163383 A JP S57163383A
- Authority
- JP
- Japan
- Prior art keywords
- neplanocin
- benzoyl
- acetyl
- compound
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229930182507 Neplanocin Natural products 0.000 title 1
- XUGWUUDOWNZAGW-VDAHYXPESA-N (1s,2r,5r)-5-(6-aminopurin-9-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1C=C(CO)[C@@H](O)[C@H]1O XUGWUUDOWNZAGW-VDAHYXPESA-N 0.000 abstract 3
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 3
- SJRJJKPEHAURKC-UHFFFAOYSA-N N-Methylmorpholine Chemical compound CN1CCOCC1 SJRJJKPEHAURKC-UHFFFAOYSA-N 0.000 abstract 3
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 3
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 3
- XUGWUUDOWNZAGW-UHFFFAOYSA-N neplanocin A Natural products C1=NC=2C(N)=NC=NC=2N1C1C=C(CO)C(O)C1O XUGWUUDOWNZAGW-UHFFFAOYSA-N 0.000 abstract 3
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 230000003327 cancerostatic effect Effects 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- JLTDJTHDQAWBAV-UHFFFAOYSA-N N,N-dimethylaniline Chemical compound CN(C)C1=CC=CC=C1 JLTDJTHDQAWBAV-UHFFFAOYSA-N 0.000 abstract 1
- 230000021736 acetylation Effects 0.000 abstract 1
- 238000006640 acetylation reaction Methods 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17640180A JPS57163383A (en) | 1980-12-12 | 1980-12-12 | Neplanocin a derivative |
| DE19813148363 DE3148363A1 (de) | 1980-12-12 | 1981-12-07 | Neplanocin a-derivate |
| FR8123093A FR2500838B1 (fr) | 1980-12-12 | 1981-12-10 | Derives de neplanocine a |
| GB08137634A GB2100721B (en) | 1980-12-12 | 1981-12-14 | Neplanocin a derivatives with antitumor activity |
| US06/776,093 US4613666A (en) | 1980-12-12 | 1985-09-16 | Neplanocin A derivatives |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17640180A JPS57163383A (en) | 1980-12-12 | 1980-12-12 | Neplanocin a derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS57163383A true JPS57163383A (en) | 1982-10-07 |
| JPS6232195B2 JPS6232195B2 (enrdf_load_stackoverflow) | 1987-07-13 |
Family
ID=16013021
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP17640180A Granted JPS57163383A (en) | 1980-12-12 | 1980-12-12 | Neplanocin a derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS57163383A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022536337A (ja) * | 2019-06-10 | 2022-08-15 | ルピン・リミテッド | Ｐｒｍｔ５阻害剤 |
-
1980
- 1980-12-12 JP JP17640180A patent/JPS57163383A/ja active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022536337A (ja) * | 2019-06-10 | 2022-08-15 | ルピン・リミテッド | Ｐｒｍｔ５阻害剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6232195B2 (enrdf_load_stackoverflow) | 1987-07-13 |
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