JPS57154182A - Omega-piperazinyl-alpha-hydroxyalkylalkylene dioxybenzenes and their acid addition salts - Google Patents
Omega-piperazinyl-alpha-hydroxyalkylalkylene dioxybenzenes and their acid addition saltsInfo
- Publication number
- JPS57154182A JPS57154182A JP3823481A JP3823481A JPS57154182A JP S57154182 A JPS57154182 A JP S57154182A JP 3823481 A JP3823481 A JP 3823481A JP 3823481 A JP3823481 A JP 3823481A JP S57154182 A JPS57154182 A JP S57154182A
- Authority
- JP
- Japan
- Prior art keywords
- piperazinyl
- acid addition
- dioxybenzenes
- hydroxyalkylalkylene
- omega
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 2
- DIXSJHCIJMTMLK-UHFFFAOYSA-N 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(4-phenylpiperazin-1-yl)ethanol Chemical compound C=1C=C2OCCOC2=CC=1C(O)CN(CC1)CCN1C1=CC=CC=C1 DIXSJHCIJMTMLK-UHFFFAOYSA-N 0.000 abstract 1
- 230000007059 acute toxicity Effects 0.000 abstract 1
- 231100000403 acute toxicity Toxicity 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000000857 drug effect Effects 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Landscapes
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3823481A JPS57154182A (en) | 1981-03-17 | 1981-03-17 | Omega-piperazinyl-alpha-hydroxyalkylalkylene dioxybenzenes and their acid addition salts |
| US06/352,716 US4684651A (en) | 1981-03-17 | 1982-02-26 | Alkylenedioxybenzene and acid addition salts thereof useful as hypotensives |
| HU82786A HU189571B (en) | 1981-03-17 | 1982-03-16 | Process for preparing alkylene-dioxy-benzene derivatives and acid addition salts thereof |
| CA000398437A CA1185240A (en) | 1981-03-17 | 1982-03-16 | Alkylenedioxybenzene derivatives and acid addition salts thereof |
| DK116982A DK152363C (da) | 1981-03-17 | 1982-03-16 | Analogifremgangsmaade til fremstilling af 3-(omega-piperazinylalkyl)-alkylendioxybenzenderivater |
| EP82102186A EP0061149B1 (en) | 1981-03-17 | 1982-03-17 | Alkylenedioxybenzene derivatives and acid addition salts thereof and a process for their preparation |
| DE8282102186T DE3261334D1 (en) | 1981-03-17 | 1982-03-17 | Alkylenedioxybenzene derivatives and acid addition salts thereof and a process for their preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3823481A JPS57154182A (en) | 1981-03-17 | 1981-03-17 | Omega-piperazinyl-alpha-hydroxyalkylalkylene dioxybenzenes and their acid addition salts |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS57154182A true JPS57154182A (en) | 1982-09-22 |
| JPS645036B2 JPS645036B2 (en, 2012) | 1989-01-27 |
Family
ID=12519604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP3823481A Granted JPS57154182A (en) | 1981-03-17 | 1981-03-17 | Omega-piperazinyl-alpha-hydroxyalkylalkylene dioxybenzenes and their acid addition salts |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS57154182A (en, 2012) |
-
1981
- 1981-03-17 JP JP3823481A patent/JPS57154182A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS645036B2 (en, 2012) | 1989-01-27 |
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