JPS57150633A - 4-benzyloxymandelic acid and its preparation - Google Patents

4-benzyloxymandelic acid and its preparation

Info

Publication number
JPS57150633A
JPS57150633A JP56035974A JP3597481A JPS57150633A JP S57150633 A JPS57150633 A JP S57150633A JP 56035974 A JP56035974 A JP 56035974A JP 3597481 A JP3597481 A JP 3597481A JP S57150633 A JPS57150633 A JP S57150633A
Authority
JP
Japan
Prior art keywords
acid
compound
preparation
formula
benzyloxymandelic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56035974A
Other languages
Japanese (ja)
Inventor
Shuji Tsuchiya
Motoo Mutsuto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nissan Chemical Corp
Original Assignee
Nissan Chemical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Corp filed Critical Nissan Chemical Corp
Priority to JP56035974A priority Critical patent/JPS57150633A/en
Publication of JPS57150633A publication Critical patent/JPS57150633A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

NEW MATERIAL:The compound of formulaI.
USE: Intermediate of 4-hydroxyphenylacetic acid or 4-hydroxymandelic acid which are important intermediates for the synthesis of pharmaceuticals.
PROCESS: The compound of formulaIis prepared by reacting benzyl phenyl ether of formula II with glyoxylic acid of formula III (commercially available about 20W50% aqueous solution) under acidic conditions in the presence of an acidic catalyst (e.g. sulfuric acid, hydrochloric acid, p-toluenesulfonic acid, etc.) preferably at 20W70°C.
COPYRIGHT: (C)1982,JPO&Japio
JP56035974A 1981-03-14 1981-03-14 4-benzyloxymandelic acid and its preparation Pending JPS57150633A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP56035974A JPS57150633A (en) 1981-03-14 1981-03-14 4-benzyloxymandelic acid and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56035974A JPS57150633A (en) 1981-03-14 1981-03-14 4-benzyloxymandelic acid and its preparation

Publications (1)

Publication Number Publication Date
JPS57150633A true JPS57150633A (en) 1982-09-17

Family

ID=12456878

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56035974A Pending JPS57150633A (en) 1981-03-14 1981-03-14 4-benzyloxymandelic acid and its preparation

Country Status (1)

Country Link
JP (1) JPS57150633A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2830861A1 (en) * 2001-10-15 2003-04-18 Rhodia Chimie Sa Production of alkoxymandelic acids, e.g. intermediates for alkoxyaromatic aldehydes, comprises reacting alkoxyaromatic compound with glyoxylic acid in presence of strong protonic acid
EP1633340A2 (en) * 2003-04-15 2006-03-15 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2830861A1 (en) * 2001-10-15 2003-04-18 Rhodia Chimie Sa Production of alkoxymandelic acids, e.g. intermediates for alkoxyaromatic aldehydes, comprises reacting alkoxyaromatic compound with glyoxylic acid in presence of strong protonic acid
EP1633340A2 (en) * 2003-04-15 2006-03-15 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
EP1633340A4 (en) * 2003-04-15 2009-05-27 Wellstat Therapeutics Corp Compounds for the treatment of metabolic disorders
US7973052B2 (en) 2003-04-15 2011-07-05 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
KR101127390B1 (en) 2003-04-15 2012-03-23 웰스태트 테러퓨틱스 코포레이션 Compounds for the treatment of metabolic disorders

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