JPS57140796A - 2'-deoxy-5-fluorouridine derivative and its preparation - Google Patents

2'-deoxy-5-fluorouridine derivative and its preparation

Info

Publication number
JPS57140796A
JPS57140796A JP20993981A JP20993981A JPS57140796A JP S57140796 A JPS57140796 A JP S57140796A JP 20993981 A JP20993981 A JP 20993981A JP 20993981 A JP20993981 A JP 20993981A JP S57140796 A JPS57140796 A JP S57140796A
Authority
JP
Japan
Prior art keywords
deoxy
preparation
acetyl
halogen
fluorouridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP20993981A
Other languages
Japanese (ja)
Inventor
Setsuo Fujii
Eiichi Sakakibara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FUNAI CORP
Funai Yakuhin Kogyo Kk
Funai Pharmaceutical Industries Ltd
Original Assignee
FUNAI CORP
Funai Yakuhin Kogyo Kk
Funai Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FUNAI CORP, Funai Yakuhin Kogyo Kk, Funai Pharmaceutical Industries Ltd filed Critical FUNAI CORP
Priority to JP20993981A priority Critical patent/JPS57140796A/en
Publication of JPS57140796A publication Critical patent/JPS57140796A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:The compound of formulaI(R is H, 1W5C alkyl, 1W4C alkoxy, acetyloxy, or halogen; n is 1W3).
EXAMPLE: 2'-Deoxy-3',5'-di-0-acetyl-5-fluoro-3-(2-methylbenzoyl)uridine.
USE: Antitumor agent administrable parenterally or crally.
PROCESS: The objective compound is prepared by reacting (A) 1mol of 2'-deoxy- 3',5'-di-0-acetyl-5-fluorouridine with (B) 1W3mol of a benzoyl halide of formula II (Hal is halogen), e.g. 2-methylbenzoyl chloride, preferably in the presence of an aromatic amine such as triethylamine, in an aprotic solvent such as dioxane.
COPYRIGHT: (C)1982,JPO&Japio
JP20993981A 1981-12-28 1981-12-28 2'-deoxy-5-fluorouridine derivative and its preparation Pending JPS57140796A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP20993981A JPS57140796A (en) 1981-12-28 1981-12-28 2'-deoxy-5-fluorouridine derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP20993981A JPS57140796A (en) 1981-12-28 1981-12-28 2'-deoxy-5-fluorouridine derivative and its preparation

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP10895578A Division JPS5535057A (en) 1978-09-05 1978-09-05 2'-deoxy-5-fluorouridine derivative, its preparation, and antitumor agent comprising it

Publications (1)

Publication Number Publication Date
JPS57140796A true JPS57140796A (en) 1982-08-31

Family

ID=16581160

Family Applications (1)

Application Number Title Priority Date Filing Date
JP20993981A Pending JPS57140796A (en) 1981-12-28 1981-12-28 2'-deoxy-5-fluorouridine derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS57140796A (en)

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