JPS57108075A - Hydrazinopyridazine compound - Google Patents

Hydrazinopyridazine compound

Info

Publication number
JPS57108075A
JPS57108075A JP18395180A JP18395180A JPS57108075A JP S57108075 A JPS57108075 A JP S57108075A JP 18395180 A JP18395180 A JP 18395180A JP 18395180 A JP18395180 A JP 18395180A JP S57108075 A JPS57108075 A JP S57108075A
Authority
JP
Japan
Prior art keywords
halogen
compound shown
compound
formulai
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP18395180A
Other languages
Japanese (ja)
Other versions
JPS6330902B2 (en
Inventor
Kikuo Yasuda
Takayuki Takezaki
Rikio Ouchi
Hiroshi Oyabu
Yoshitaka Tanimoto
Toshimi Seki
Takashi Yamaguchi
Akihiro Izumi
Norio Himori
Tsutomu Ishimori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aska Pharmaceutical Co Ltd
Original Assignee
Teikoku Hormone Manufacturing Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teikoku Hormone Manufacturing Co Ltd filed Critical Teikoku Hormone Manufacturing Co Ltd
Priority to JP18395180A priority Critical patent/JPS57108075A/en
Publication of JPS57108075A publication Critical patent/JPS57108075A/en
Publication of JPS6330902B2 publication Critical patent/JPS6330902B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

NEW MATERIAL:A compound shown by the formulaI[R1 is CN, OH, aryloxy, aryl, halogen, alkyl which may have substituent group (acetylamino, halogen, OH, etc.), methoxy or ethoxy which may have substituent group (2-furyl, phenyl, etc.) R2 and R3 are H, halogen, alkyl, or alkoxy; R4 and R5 are H or CH3; X is O or S; Y is NH2 or group shown by the formula II] and its salt.
EXAMPLE: 1-( 2-Cyanophenoxy )-3-[ 1,1-dimethyl-2-( 3-hydrazino-6-pyridazinyloxy ) ethylamino]-2-propanol.
USE: A hypotensor. Most of the compounds have improved β-blocking action together with vasodilating action.
PROCESS: A compound shown by the formula III (X is halogen) is reacted with hydrazine or its hydrate, and, if necessary, with acetone, to give a compound shown by the formulaI.
COPYRIGHT: (C)1982,JPO&Japio
JP18395180A 1980-12-26 1980-12-26 Hydrazinopyridazine compound Granted JPS57108075A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP18395180A JPS57108075A (en) 1980-12-26 1980-12-26 Hydrazinopyridazine compound

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18395180A JPS57108075A (en) 1980-12-26 1980-12-26 Hydrazinopyridazine compound

Publications (2)

Publication Number Publication Date
JPS57108075A true JPS57108075A (en) 1982-07-05
JPS6330902B2 JPS6330902B2 (en) 1988-06-21

Family

ID=16144666

Family Applications (1)

Application Number Title Priority Date Filing Date
JP18395180A Granted JPS57108075A (en) 1980-12-26 1980-12-26 Hydrazinopyridazine compound

Country Status (1)

Country Link
JP (1) JPS57108075A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0092945A2 (en) * 1982-04-23 1983-11-02 Imperial Chemical Industries Plc Nitrogeneous compounds
JPS58225069A (en) * 1982-06-23 1983-12-27 Teikoku Hormone Mfg Co Ltd Hydrazinopyridazine derivative

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01128703U (en) * 1988-02-23 1989-09-01
JPH01153104U (en) * 1988-04-15 1989-10-23

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0092945A2 (en) * 1982-04-23 1983-11-02 Imperial Chemical Industries Plc Nitrogeneous compounds
US4711887A (en) * 1982-04-23 1987-12-08 Imperial Chemical Industries Plc Hydrazinopyridazine compounds
JPS58225069A (en) * 1982-06-23 1983-12-27 Teikoku Hormone Mfg Co Ltd Hydrazinopyridazine derivative
JPS6334151B2 (en) * 1982-06-23 1988-07-08 Teikoku Hormone Mfg Co Ltd

Also Published As

Publication number Publication date
JPS6330902B2 (en) 1988-06-21

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