JPS57134471A - Novel sydnonimine derivative, its preparation, and drug containing said derivative as active component - Google Patents

Novel sydnonimine derivative, its preparation, and drug containing said derivative as active component

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Publication number
JPS57134471A
JPS57134471A JP1892481A JP1892481A JPS57134471A JP S57134471 A JPS57134471 A JP S57134471A JP 1892481 A JP1892481 A JP 1892481A JP 1892481 A JP1892481 A JP 1892481A JP S57134471 A JPS57134471 A JP S57134471A
Authority
JP
Japan
Prior art keywords
derivative
piperazin
sydnonimine
novel
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1892481A
Other languages
Japanese (ja)
Inventor
Hiroyoshi Hidaka
Ikuo Matsumoto
Junji Furusawa
Shigenori Kotani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to JP1892481A priority Critical patent/JPS57134471A/en
Publication of JPS57134471A publication Critical patent/JPS57134471A/en
Pending legal-status Critical Current

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  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:3-[4-( 5-Phenyl -5- oxopentyl )-piperazin -1- yl]-sydnonimine of formula or its acid addition salt.
USE: Agents for improving the cardio-vascular disorder, e.g. agent for improving peripheral circulation, coronary vessel dilating agent, remedy for cerebral thrombosis, etc. Useful for the prevention and remedy of cardio-vascular disorder. It is low toxic and has blood platelet coagulation inhibiting and vascular wall relaxing activities. The characteristic feature of the compound is presence of keto group in the substituent group.
PROCESS: The compound of formula can be prepared by the ring closing reaction of 5-[4-(N-nitrosocyanomethylamino)-piperazin-1-yl]-valerophenone obtained by the nitrosation of 5-(4-cyanomethylamino-piperazin-1-yl)-valerophenone.
COPYRIGHT: (C)1982,JPO&Japio
JP1892481A 1981-02-13 1981-02-13 Novel sydnonimine derivative, its preparation, and drug containing said derivative as active component Pending JPS57134471A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1892481A JPS57134471A (en) 1981-02-13 1981-02-13 Novel sydnonimine derivative, its preparation, and drug containing said derivative as active component

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1892481A JPS57134471A (en) 1981-02-13 1981-02-13 Novel sydnonimine derivative, its preparation, and drug containing said derivative as active component

Publications (1)

Publication Number Publication Date
JPS57134471A true JPS57134471A (en) 1982-08-19

Family

ID=11985163

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1892481A Pending JPS57134471A (en) 1981-02-13 1981-02-13 Novel sydnonimine derivative, its preparation, and drug containing said derivative as active component

Country Status (1)

Country Link
JP (1) JPS57134471A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0073345A2 (en) * 1981-08-24 1983-03-09 Hiroyoshi Hidaka Sydnonimine derivatives, process for production thereof, and use thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0073345A2 (en) * 1981-08-24 1983-03-09 Hiroyoshi Hidaka Sydnonimine derivatives, process for production thereof, and use thereof

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