JPS57134471A - Novel sydnonimine derivative, its preparation, and drug containing said derivative as active component - Google Patents
Novel sydnonimine derivative, its preparation, and drug containing said derivative as active componentInfo
- Publication number
- JPS57134471A JPS57134471A JP1892481A JP1892481A JPS57134471A JP S57134471 A JPS57134471 A JP S57134471A JP 1892481 A JP1892481 A JP 1892481A JP 1892481 A JP1892481 A JP 1892481A JP S57134471 A JPS57134471 A JP S57134471A
- Authority
- JP
- Japan
- Prior art keywords
- derivative
- piperazin
- sydnonimine
- novel
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:3-[4-( 5-Phenyl -5- oxopentyl )-piperazin -1- yl]-sydnonimine of formula or its acid addition salt.
USE: Agents for improving the cardio-vascular disorder, e.g. agent for improving peripheral circulation, coronary vessel dilating agent, remedy for cerebral thrombosis, etc. Useful for the prevention and remedy of cardio-vascular disorder. It is low toxic and has blood platelet coagulation inhibiting and vascular wall relaxing activities. The characteristic feature of the compound is presence of keto group in the substituent group.
PROCESS: The compound of formula can be prepared by the ring closing reaction of 5-[4-(N-nitrosocyanomethylamino)-piperazin-1-yl]-valerophenone obtained by the nitrosation of 5-(4-cyanomethylamino-piperazin-1-yl)-valerophenone.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1892481A JPS57134471A (en) | 1981-02-13 | 1981-02-13 | Novel sydnonimine derivative, its preparation, and drug containing said derivative as active component |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1892481A JPS57134471A (en) | 1981-02-13 | 1981-02-13 | Novel sydnonimine derivative, its preparation, and drug containing said derivative as active component |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57134471A true JPS57134471A (en) | 1982-08-19 |
Family
ID=11985163
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1892481A Pending JPS57134471A (en) | 1981-02-13 | 1981-02-13 | Novel sydnonimine derivative, its preparation, and drug containing said derivative as active component |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57134471A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0073345A2 (en) * | 1981-08-24 | 1983-03-09 | Hiroyoshi Hidaka | Sydnonimine derivatives, process for production thereof, and use thereof |
-
1981
- 1981-02-13 JP JP1892481A patent/JPS57134471A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0073345A2 (en) * | 1981-08-24 | 1983-03-09 | Hiroyoshi Hidaka | Sydnonimine derivatives, process for production thereof, and use thereof |
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