JPS57123174A - 3,4-disubstituted 1,2,5-oxadiazole-2-oxide, manufacture and pharmaceutical blend containing same - Google Patents

3,4-disubstituted 1,2,5-oxadiazole-2-oxide, manufacture and pharmaceutical blend containing same

Info

Publication number
JPS57123174A
JPS57123174A JP56202599A JP20259981A JPS57123174A JP S57123174 A JPS57123174 A JP S57123174A JP 56202599 A JP56202599 A JP 56202599A JP 20259981 A JP20259981 A JP 20259981A JP S57123174 A JPS57123174 A JP S57123174A
Authority
JP
Japan
Prior art keywords
denotes
see diagramm
conhr
oxadiazole
atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56202599A
Other languages
English (en)
Inventor
Shieenafuingeru Karuru
Baierure Ruudei
Mogirefu Anton
Boon Herumuto
Yusuto Meritsuta
Aa Marutorana Piero
Nitsutsu Rorufuueberuharuto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cassella Farbwerke Mainkur AG
Original Assignee
Cassella Farbwerke Mainkur AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cassella Farbwerke Mainkur AG filed Critical Cassella Farbwerke Mainkur AG
Publication of JPS57123174A publication Critical patent/JPS57123174A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/08—1,2,5-Oxadiazoles; Hydrogenated 1,2,5-oxadiazoles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Chemical Treatment Of Metals (AREA)
  • Preventing Corrosion Or Incrustation Of Metals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP56202599A 1980-12-18 1981-12-17 3,4-disubstituted 1,2,5-oxadiazole-2-oxide, manufacture and pharmaceutical blend containing same Pending JPS57123174A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803047749 DE3047749A1 (de) 1980-12-18 1980-12-18 3,4-disubstituierte 1,2,5-oxdiazol-2-oxide, verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische zubereitungen

Publications (1)

Publication Number Publication Date
JPS57123174A true JPS57123174A (en) 1982-07-31

Family

ID=6119512

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56202599A Pending JPS57123174A (en) 1980-12-18 1981-12-17 3,4-disubstituted 1,2,5-oxadiazole-2-oxide, manufacture and pharmaceutical blend containing same

Country Status (14)

Country Link
EP (1) EP0054873B1 (ja)
JP (1) JPS57123174A (ja)
AT (1) ATE9692T1 (ja)
AU (1) AU7855781A (ja)
CA (1) CA1173034A (ja)
DD (1) DD202019A5 (ja)
DE (2) DE3047749A1 (ja)
DK (1) DK533781A (ja)
ES (1) ES8300102A1 (ja)
HU (1) HU183750B (ja)
NO (1) NO814097L (ja)
PL (1) PL234258A1 (ja)
SU (1) SU1152519A3 (ja)
ZA (1) ZA818725B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4507485A (en) * 1984-01-23 1985-03-26 Bristol-Myers Company 3,4-Disubstituted-1,2,5-oxadiazoles having histamine H2 -receptor antagonist activity
DE4217794A1 (de) * 1992-05-29 1993-12-02 Cassella Ag Phenylfuroxane
DE4218582A1 (de) * 1992-06-05 1993-12-09 Cassella Ag Pyridyl-1,2,5-oxadiazol-carbonamid-2-oxide
DE4218979A1 (de) * 1992-06-10 1993-12-16 Cassella Ag Pyrimidofuroxane
DE4220264A1 (de) * 1992-06-20 1993-12-23 Cassella Ag Phenyl-1,2,5-oxadiazol-carbonamid-2-oxide
DE4223800A1 (de) * 1992-07-20 1994-01-27 Cassella Farbwerke Mainkur Ag Verwendung von 1.2.5-Oxadiazol-2-oxiden zur Behandlung erektiler Dysfunktionen
DE4401150A1 (de) * 1994-01-17 1995-07-20 Cassella Ag Furazancarbonsäurederivate

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH498854A (de) * 1968-02-06 1970-11-15 Geigy Ag J R Verfahren zur Herstellung von neuen Furazanderivaten
GB1474692A (en) * 1973-05-21 1977-05-25 Ici Ltd Furoxan production

Also Published As

Publication number Publication date
ES508087A0 (es) 1982-10-01
CA1173034A (en) 1984-08-21
DE3166527D1 (en) 1984-11-08
SU1152519A3 (en) 1985-04-23
EP0054873A1 (de) 1982-06-30
AU7855781A (en) 1982-06-24
ES8300102A1 (es) 1982-10-01
PL234258A1 (ja) 1982-08-02
DD202019A5 (de) 1983-08-24
ATE9692T1 (de) 1984-10-15
ZA818725B (en) 1982-11-24
NO814097L (no) 1982-06-21
EP0054873B1 (de) 1984-10-03
DE3047749A1 (de) 1982-07-22
HU183750B (en) 1984-05-28
DK533781A (da) 1982-06-19

Similar Documents

Publication Publication Date Title
JPS5611932A (en) Stabilized polymer composition
ZA855492B (en) Novel n-hydroxyl protecting groups and process for the preparation of 3-acylamino-1-hydroxy-2-azetidinones
EP0048763A4 (en) ACYLAMINO ACIDS CONTAINING SULFUR.
JPS55164678A (en) Novel cyclic imidazolecyanoguanidine
JPS57123174A (en) 3,4-disubstituted 1,2,5-oxadiazole-2-oxide, manufacture and pharmaceutical blend containing same
DK0382660T3 (da) Dioxaphosphorinanforbindelser og dermed stabiliserede polyolefinmaterialer
ZA811130B (en) Benzoxazoles and benzothiazoles,process for their preparation,and pharmaceutical compositions containing these compounds
ZA821850B (en) Nitroanilines,processes for preparing these and herbicidal compositions thereof
JPS5455565A (en) Novel thiazolidine derivative
NO940265D0 (no) Fremgangsmaate ved fremstilling av svovelholdige karboksylsyreamider
DE3260297D1 (en) 4"-modified methylene oleandomycins
ATE13288T1 (de) Halogenverbindungen und feuerhemmende polymerkompositionen in denen diese verbindungen eingeschlossen sind.
ES2024332A6 (es) Procedimiento para la obtencion de nuevas sulfonamidas.
ATE68483T1 (de) Dipercarbonsaeuren und bleichmittel.
DE3061105D1 (en) Pyrazolin-5-on-yl-methyl-(di)thiophosphoric acid esters, process for their preparation and their use as pesticides
JPS649252A (en) Radiation-resistant polyolefin composition
TH18904A (th) สารผสมที่มีสารประกอบเบนโซไดฟิวราโนนและวิธีทำวัสดุชนิดไม่ชอบน้ำให้มีสีโดยการใช้สารผสมนี้
TH2354EX (th) อนุพันธ์ของไตรคลอโรอาคริลโลอิลออกซึมกระบวนการสำหรับเตรียมสารเหล่านี้และสารกำจัดเชื้อราในการเกษตร
DK0438096T3 (da) Stabilisatorer til ethylen/chlortrifluorethylencopolymersammensætninger
TH18904EX (th) สารผสมที่มีสารประกอบเบนโซไดฟิวราโนนและวิธีทำวัสดุชนิดไม่ชอบน้ำให้มีสีโดยการใช้สารผสมนี้
ATE54459T1 (de) Polyaetheramidzusammensetzungen aus bizyklischen amidacetalen und bis- und polyphenolverbindungen.
JPS5734154A (en) Room temperature-curing composition
JPS5610191A (en) Clavulanic acid derivative* its manufacture and composition
EP0273357A3 (en) Fluorine-containing macrolide compounds, pharmaceutical compositions comprising the same and their use for the manufacture of medicaments