JPS57114554A - N-substituted derivative of validamine, its preparation, and alpha-glucosidase inhibiting agent - Google Patents
N-substituted derivative of validamine, its preparation, and alpha-glucosidase inhibiting agentInfo
- Publication number
- JPS57114554A JPS57114554A JP56181A JP56181A JPS57114554A JP S57114554 A JPS57114554 A JP S57114554A JP 56181 A JP56181 A JP 56181A JP 56181 A JP56181 A JP 56181A JP S57114554 A JPS57114554 A JP S57114554A
- Authority
- JP
- Japan
- Prior art keywords
- validamine
- glucosidase inhibiting
- inhibiting agent
- derivative
- alpha
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- GSQYAWMREAXBHF-UOYQFSTFSA-N validamine Chemical class N[C@H]1C[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O GSQYAWMREAXBHF-UOYQFSTFSA-N 0.000 title abstract 5
- 102100024295 Maltase-glucoamylase Human genes 0.000 title abstract 3
- 108010028144 alpha-Glucosidases Proteins 0.000 title abstract 3
- 230000002401 inhibitory effect Effects 0.000 title abstract 3
- GSQYAWMREAXBHF-UHFFFAOYSA-N Validamine Natural products NC1CC(CO)C(O)C(O)C1O GSQYAWMREAXBHF-UHFFFAOYSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- -1 phenoxy, thienyl Chemical group 0.000 abstract 2
- 125000004076 pyridyl group Chemical group 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 239000002262 Schiff base Substances 0.000 abstract 1
- 150000004753 Schiff bases Chemical class 0.000 abstract 1
- 150000001299 aldehydes Chemical class 0.000 abstract 1
- 239000003674 animal food additive Substances 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 235000014633 carbohydrates Nutrition 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
- 208000002925 dental caries Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 235000013373 food additive Nutrition 0.000 abstract 1
- 239000002778 food additive Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 201000001421 hyperglycemia Diseases 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Landscapes
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56181A JPS57114554A (en) | 1981-01-05 | 1981-01-05 | N-substituted derivative of validamine, its preparation, and alpha-glucosidase inhibiting agent |
EP81306141A EP0056194B1 (en) | 1981-01-05 | 1981-12-24 | N-substituted pseudo-aminosugars, their production and use |
DE8181306141T DE3166093D1 (en) | 1981-01-05 | 1981-12-24 | N-substituted pseudo-aminosugars, their production and use |
US06/334,986 US4701559A (en) | 1981-01-05 | 1981-12-28 | N-substituted pseudo-aminosugars, their production and use |
CA000393545A CA1184181A (en) | 1981-01-05 | 1982-01-04 | N-substituted pseudo-aminosugars, their production and use |
US07/039,277 US4803303A (en) | 1981-01-05 | 1987-04-17 | N-substituted pseudo-aminosugars, their production and use |
US07/039,278 US4777294A (en) | 1981-01-05 | 1987-04-17 | N-substituted pseudo-aminosugars, their production and use |
MX9202937A MX9202937A (es) | 1981-01-05 | 1992-06-17 | Pseudo-aminoazucares n-substituidos. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56181A JPS57114554A (en) | 1981-01-05 | 1981-01-05 | N-substituted derivative of validamine, its preparation, and alpha-glucosidase inhibiting agent |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57114554A true JPS57114554A (en) | 1982-07-16 |
JPH0161100B2 JPH0161100B2 (enrdf_load_stackoverflow) | 1989-12-27 |
Family
ID=11477129
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56181A Granted JPS57114554A (en) | 1981-01-05 | 1981-01-05 | N-substituted derivative of validamine, its preparation, and alpha-glucosidase inhibiting agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57114554A (enrdf_load_stackoverflow) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012011174A1 (ja) * | 2010-07-22 | 2012-01-26 | ビオフェルミン製薬株式会社 | 脂質代謝改善剤、脂質代謝改善作用増強剤、抗肥満剤及び抗肥満作用増強剤 |
-
1981
- 1981-01-05 JP JP56181A patent/JPS57114554A/ja active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012011174A1 (ja) * | 2010-07-22 | 2012-01-26 | ビオフェルミン製薬株式会社 | 脂質代謝改善剤、脂質代謝改善作用増強剤、抗肥満剤及び抗肥満作用増強剤 |
Also Published As
Publication number | Publication date |
---|---|
JPH0161100B2 (enrdf_load_stackoverflow) | 1989-12-27 |
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