JPS57200335A - N-substituted derivative of valiolamine, its preparation and use - Google Patents

N-substituted derivative of valiolamine, its preparation and use

Info

Publication number
JPS57200335A
JPS57200335A JP8463581A JP8463581A JPS57200335A JP S57200335 A JPS57200335 A JP S57200335A JP 8463581 A JP8463581 A JP 8463581A JP 8463581 A JP8463581 A JP 8463581A JP S57200335 A JPS57200335 A JP S57200335A
Authority
JP
Japan
Prior art keywords
valiolamine
substituted
furyl
thienyl
phenoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP8463581A
Other languages
Japanese (ja)
Other versions
JPH0238580B2 (en
Inventor
Satoshi Horii
Yukihiko Kameda
Hiroshi Fukase
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP8463581A priority Critical patent/JPH0238580B2/en
Priority to EP81306141A priority patent/EP0056194B1/en
Priority to DE8181306141T priority patent/DE3166093D1/en
Priority to US06/334,986 priority patent/US4701559A/en
Priority to CA000393545A priority patent/CA1184181A/en
Publication of JPS57200335A publication Critical patent/JPS57200335A/en
Priority to US07/039,278 priority patent/US4777294A/en
Priority to US07/039,277 priority patent/US4803303A/en
Publication of JPH0238580B2 publication Critical patent/JPH0238580B2/en
Priority to MX9202937A priority patent/MX9202937A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

NEW MATERIAL:The valiolamine derivative of formula[A is 1W10C chain hydrocarbon group which may be substituted with OH, phenoxy, thienyl, furyl, pyridyl, cyclohexyl, or (substituted) phenyl].
EXAMPLE: N-Benzyl valiolamine.
USE: Remedy for obesity, adiposis, hyperlipemia, diabetes, prediabetes, and diseases caused by the sugar metabolism by oral microorganisms. It is an α-glycosidase- inhibiting agent, and suppresses the hydrocarbon metabolism of animals other than human.
PROCESS: The compound of formula can be prepared by reacting e.g. a 1W10C chain aldehyde or ketone which may be substituted with OH, phenoxy, thienyl, furyl, pyridyl, cyclohexyl or (substituted) phenyl, with valiolamine, and reducing the product.
COPYRIGHT: (C)1982,JPO&Japio
JP8463581A 1981-01-05 1981-06-02 BARIOORUAMINNONNCHIKANJUDOTAI * SONOSEIZOHOOYOBYOTO Expired - Lifetime JPH0238580B2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP8463581A JPH0238580B2 (en) 1981-06-02 1981-06-02 BARIOORUAMINNONNCHIKANJUDOTAI * SONOSEIZOHOOYOBYOTO
EP81306141A EP0056194B1 (en) 1981-01-05 1981-12-24 N-substituted pseudo-aminosugars, their production and use
DE8181306141T DE3166093D1 (en) 1981-01-05 1981-12-24 N-substituted pseudo-aminosugars, their production and use
US06/334,986 US4701559A (en) 1981-01-05 1981-12-28 N-substituted pseudo-aminosugars, their production and use
CA000393545A CA1184181A (en) 1981-01-05 1982-01-04 N-substituted pseudo-aminosugars, their production and use
US07/039,277 US4803303A (en) 1981-01-05 1987-04-17 N-substituted pseudo-aminosugars, their production and use
US07/039,278 US4777294A (en) 1981-01-05 1987-04-17 N-substituted pseudo-aminosugars, their production and use
MX9202937A MX9202937A (en) 1981-01-05 1992-06-17 PSEUDO-AMINOAZUCARES N-SUBSTITUTED.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8463581A JPH0238580B2 (en) 1981-06-02 1981-06-02 BARIOORUAMINNONNCHIKANJUDOTAI * SONOSEIZOHOOYOBYOTO

Publications (2)

Publication Number Publication Date
JPS57200335A true JPS57200335A (en) 1982-12-08
JPH0238580B2 JPH0238580B2 (en) 1990-08-31

Family

ID=13836137

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8463581A Expired - Lifetime JPH0238580B2 (en) 1981-01-05 1981-06-02 BARIOORUAMINNONNCHIKANJUDOTAI * SONOSEIZOHOOYOBYOTO

Country Status (1)

Country Link
JP (1) JPH0238580B2 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09323940A (en) * 1996-04-05 1997-12-16 Takeda Chem Ind Ltd Medicine composition
US5840705A (en) * 1995-04-20 1998-11-24 The Hokuren Federation Of Agricultural Cooperatives α-glucosidase inhibitor, composition principally comprising sugar and containing the same, sweetener, food and feed
WO2007037423A1 (en) * 2005-09-29 2007-04-05 Kureha Corporation Antidiabetic agent
WO2007072564A1 (en) * 2005-12-22 2007-06-28 Japan Health Sciences Foundation Remedy/preventive for heart failure
WO2012011174A1 (en) * 2010-07-22 2012-01-26 ビオフェルミン製薬株式会社 Lipid metabolism improving agent, agent for enhancing lipid metabolism improving action, anti-obesity agent, and agent for enhancing anti-obesity action

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100956490B1 (en) * 2005-05-27 2010-05-07 주식회사유한양행 A process for preparing pseudo-aminosugars using new dehalogenation reagent

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840705A (en) * 1995-04-20 1998-11-24 The Hokuren Federation Of Agricultural Cooperatives α-glucosidase inhibitor, composition principally comprising sugar and containing the same, sweetener, food and feed
JPH09323940A (en) * 1996-04-05 1997-12-16 Takeda Chem Ind Ltd Medicine composition
JP2008195736A (en) * 1996-04-05 2008-08-28 Takeda Chem Ind Ltd Pharmaceutical composition
WO2007037423A1 (en) * 2005-09-29 2007-04-05 Kureha Corporation Antidiabetic agent
JP4966859B2 (en) * 2005-09-29 2012-07-04 智 熊沢 Antidiabetic
WO2007072564A1 (en) * 2005-12-22 2007-06-28 Japan Health Sciences Foundation Remedy/preventive for heart failure
WO2012011174A1 (en) * 2010-07-22 2012-01-26 ビオフェルミン製薬株式会社 Lipid metabolism improving agent, agent for enhancing lipid metabolism improving action, anti-obesity agent, and agent for enhancing anti-obesity action

Also Published As

Publication number Publication date
JPH0238580B2 (en) 1990-08-31

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Legal Events

Date Code Title Description
EXPY Cancellation because of completion of term