JPS57106696A - 1-(beta-d-arabinofuranosyl)cytosine derivative and its preparation - Google Patents
1-(beta-d-arabinofuranosyl)cytosine derivative and its preparationInfo
- Publication number
- JPS57106696A JPS57106696A JP55182777A JP18277780A JPS57106696A JP S57106696 A JPS57106696 A JP S57106696A JP 55182777 A JP55182777 A JP 55182777A JP 18277780 A JP18277780 A JP 18277780A JP S57106696 A JPS57106696 A JP S57106696A
- Authority
- JP
- Japan
- Prior art keywords
- arabinofuranosyl
- amino
- protecting group
- cytosine
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- UHDGCWIWMRVCDJ-CCXZUQQUSA-N Cytarabine Chemical class O=C1N=C(N)C=CN1[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O1 UHDGCWIWMRVCDJ-CCXZUQQUSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- UHDGCWIWMRVCDJ-UHFFFAOYSA-N 1-beta-D-Xylofuranosyl-NH-Cytosine Natural products O=C1N=C(N)C=CN1C1C(O)C(O)C(CO)O1 UHDGCWIWMRVCDJ-UHFFFAOYSA-N 0.000 abstract 1
- UHDGCWIWMRVCDJ-YDKYIBAVSA-N 4-amino-1-[(2r,3s,4r,5r)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one Chemical compound O=C1N=C(N)C=CN1[C@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O1 UHDGCWIWMRVCDJ-YDKYIBAVSA-N 0.000 abstract 1
- MPZGQWSSRIZVPF-XSPKLOCKSA-N O[C@H]1[C@H](O)[C@@H](C(O)=P(=O)CCN)O[C@H]1N1C(=O)N=C(N)C=C1 Chemical compound O[C@H]1[C@H](O)[C@@H](C(O)=P(=O)CCN)O[C@H]1N1C(=O)N=C(N)C=C1 MPZGQWSSRIZVPF-XSPKLOCKSA-N 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 150000001447 alkali salts Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- -1 amino- protected amino Chemical group 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP55182777A JPS57106696A (en) | 1980-12-25 | 1980-12-25 | 1-(beta-d-arabinofuranosyl)cytosine derivative and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP55182777A JPS57106696A (en) | 1980-12-25 | 1980-12-25 | 1-(beta-d-arabinofuranosyl)cytosine derivative and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS57106696A true JPS57106696A (en) | 1982-07-02 |
| JPS636080B2 JPS636080B2 (enrdf_load_stackoverflow) | 1988-02-08 |
Family
ID=16124227
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP55182777A Granted JPS57106696A (en) | 1980-12-25 | 1980-12-25 | 1-(beta-d-arabinofuranosyl)cytosine derivative and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS57106696A (enrdf_load_stackoverflow) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5993100A (ja) * | 1983-10-31 | 1984-05-29 | Wakunaga Seiyaku Kk | オリゴヌクレオチド誘導体 |
| JPS6191196A (ja) * | 1984-10-09 | 1986-05-09 | Toyama Chem Co Ltd | 新規な５―フルオロ―２´―デオキシウリジン―５´―ホスフェート誘導体およびその塩並びにそれらを含有する抗腫瘍剤 |
| WO2003016423A1 (en) * | 2001-08-20 | 2003-02-27 | Japan Science And Technology Corporation | Hydrogelation agents |
| US7196178B2 (en) | 2001-08-07 | 2007-03-27 | Japan Science And Technology Agency | Sugar-derived gellant for hydrogel formation |
-
1980
- 1980-12-25 JP JP55182777A patent/JPS57106696A/ja active Granted
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5993100A (ja) * | 1983-10-31 | 1984-05-29 | Wakunaga Seiyaku Kk | オリゴヌクレオチド誘導体 |
| JPS6191196A (ja) * | 1984-10-09 | 1986-05-09 | Toyama Chem Co Ltd | 新規な５―フルオロ―２´―デオキシウリジン―５´―ホスフェート誘導体およびその塩並びにそれらを含有する抗腫瘍剤 |
| US7196178B2 (en) | 2001-08-07 | 2007-03-27 | Japan Science And Technology Agency | Sugar-derived gellant for hydrogel formation |
| WO2003016423A1 (en) * | 2001-08-20 | 2003-02-27 | Japan Science And Technology Corporation | Hydrogelation agents |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS636080B2 (enrdf_load_stackoverflow) | 1988-02-08 |
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