JPS57106694A - Anthracycline glycoside - Google Patents

Anthracycline glycoside

Info

Publication number
JPS57106694A
JPS57106694A JP56172203A JP17220381A JPS57106694A JP S57106694 A JPS57106694 A JP S57106694A JP 56172203 A JP56172203 A JP 56172203A JP 17220381 A JP17220381 A JP 17220381A JP S57106694 A JPS57106694 A JP S57106694A
Authority
JP
Japan
Prior art keywords
group
hydrogen atom
amino
hydroxy group
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56172203A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6328079B2 (enrdf_load_stackoverflow
Inventor
Barujiotsuchi Aruberuto
Katsushineri Jiyuzetsupe
Penko Serujio
Arukamone Fuederiko
Kasatsuza Annamaria
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carlo Erba SpA filed Critical Carlo Erba SpA
Publication of JPS57106694A publication Critical patent/JPS57106694A/ja
Publication of JPS6328079B2 publication Critical patent/JPS6328079B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP56172203A 1980-11-01 1981-10-29 Anthracycline glycoside Granted JPS57106694A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8035195 1980-11-01

Publications (2)

Publication Number Publication Date
JPS57106694A true JPS57106694A (en) 1982-07-02
JPS6328079B2 JPS6328079B2 (enrdf_load_stackoverflow) 1988-06-07

Family

ID=10517034

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56172203A Granted JPS57106694A (en) 1980-11-01 1981-10-29 Anthracycline glycoside

Country Status (6)

Country Link
US (1) US4393052A (enrdf_load_stackoverflow)
EP (1) EP0051279B1 (enrdf_load_stackoverflow)
JP (1) JPS57106694A (enrdf_load_stackoverflow)
AT (1) ATE15375T1 (enrdf_load_stackoverflow)
CA (1) CA1175420A (enrdf_load_stackoverflow)
DE (2) DE3172152D1 (enrdf_load_stackoverflow)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5138042A (en) * 1981-05-28 1992-08-11 Farmitalia Carlo Erba S.P.A. 6-deoxyanthracyclines
CA1248944A (en) * 1982-09-28 1989-01-17 Gareth J. Thomas Anthracycline glycosides
GB8508079D0 (en) * 1985-03-28 1985-05-01 Erba Farmitalia Antitumor anthracyclines
JPH01161986U (enrdf_load_stackoverflow) * 1988-04-28 1989-11-10
US4997922A (en) * 1988-09-06 1991-03-05 Sanraku Incorporated Anthracycline derivatives
DE3842836A1 (de) * 1988-12-20 1990-06-21 Behringwerke Ag Rhodomycine mit einer modifizierten kohlenhydrat-einheit
GB9216962D0 (en) * 1992-08-11 1992-09-23 Erba Carlo Spa Therapeutically active naphthalenesulfonic-pyrrolecarboxamido derivatives
KR0160542B1 (ko) * 1994-12-15 1999-02-01 정선종 모노리틱 마이크로 웨이브 집적회로용 기판 및 그 제조방법
GB0114654D0 (en) * 2001-06-15 2001-08-08 Pharmacia & Upjohn Spa Anti-tumor compound

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5636498A (en) * 1979-09-01 1981-04-09 Erba Carlo Spa Anthracycline glycoside* its manufacture and pharmaceutic composition containing it and having anticancer and antileukemic activity

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1457632A (en) * 1974-03-22 1976-12-08 Farmaceutici Italia Adriamycins
GB1462387A (en) * 1974-05-02 1977-01-26 Farmaceutici Italia Aminoglycosides
US4020270A (en) * 1974-05-02 1977-04-26 Societa' Farmaceutici Italia S.P.A. L-lyxohex-1-enopyranose derivative
US4039663A (en) * 1975-03-19 1977-08-02 Societa' Farmaceutici Italia S.P.A. Daunomycins, process for their uses and intermediates
GB1511559A (en) * 1975-09-26 1978-05-24 Farmaceutici Italia Anthracycline glycosides
US4265885A (en) * 1978-10-25 1981-05-05 Farmitalia Carlo Erba S.P.A. Anthracyclines containing branched-chain amino-deoxy sugars
GB2034707B (en) * 1978-10-25 1982-09-15 Erba Farmitalia anthracycline glycosides
US4254110A (en) * 1979-02-02 1981-03-03 Farmitalia Carlo Erba S.P.A. Pentofuranosyl anthracyclines, intermediates in and method for their preparation and compositions and use thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5636498A (en) * 1979-09-01 1981-04-09 Erba Carlo Spa Anthracycline glycoside* its manufacture and pharmaceutic composition containing it and having anticancer and antileukemic activity

Also Published As

Publication number Publication date
EP0051279B1 (en) 1985-09-04
US4393052A (en) 1983-07-12
CA1175420A (en) 1984-10-02
DE51279T1 (de) 1983-05-26
ATE15375T1 (de) 1985-09-15
DE3172152D1 (en) 1985-10-10
EP0051279A1 (en) 1982-05-12
JPS6328079B2 (enrdf_load_stackoverflow) 1988-06-07

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