JPS5699414A - Antitumorigenic agent - Google Patents
Antitumorigenic agentInfo
- Publication number
- JPS5699414A JPS5699414A JP244080A JP244080A JPS5699414A JP S5699414 A JPS5699414 A JP S5699414A JP 244080 A JP244080 A JP 244080A JP 244080 A JP244080 A JP 244080A JP S5699414 A JPS5699414 A JP S5699414A
- Authority
- JP
- Japan
- Prior art keywords
- uracil
- fluoro compound
- antitumorigenic
- agent
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
PURPOSE: An antitumorigenic agent that is made by adding a uracil to a specific fluoro compound whereby the antitumorgenic activity of the fluoro compound is extremely increased and the toxicity becomes low.
CONSTITUTION: Ethyl 6-n-butoxy-5-fluorohexahydro-2,4-dioxopyrimidine-5-carboxylate (abbreviated to fluoro compound hereinafter) is combined with at least one selected from uracils consisting of uracil, thymine and thymidine to give the antitumorigenic agent. The amount of the uracil is preferably 0.5W100mol/mol of the fluoro compound. Although a uracil itself has no antitumorigenic activity, the combination with the fluoro compound markedly increase the effect of the compound. Further, the titled antitumorigenic agent scarcely develops toxicity.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP244080A JPS5699414A (en) | 1980-01-11 | 1980-01-11 | Antitumorigenic agent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP244080A JPS5699414A (en) | 1980-01-11 | 1980-01-11 | Antitumorigenic agent |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5699414A true JPS5699414A (en) | 1981-08-10 |
JPS6312845B2 JPS6312845B2 (en) | 1988-03-23 |
Family
ID=11529324
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP244080A Granted JPS5699414A (en) | 1980-01-11 | 1980-01-11 | Antitumorigenic agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5699414A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4719213A (en) * | 1977-04-05 | 1988-01-12 | Taiho Pharmaceutical Company Limited | Anti-cancer composition for delivering 5-fluorouracil |
-
1980
- 1980-01-11 JP JP244080A patent/JPS5699414A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4719213A (en) * | 1977-04-05 | 1988-01-12 | Taiho Pharmaceutical Company Limited | Anti-cancer composition for delivering 5-fluorouracil |
Also Published As
Publication number | Publication date |
---|---|
JPS6312845B2 (en) | 1988-03-23 |
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