JPS5699414A - Antitumorigenic agent - Google Patents

Antitumorigenic agent

Info

Publication number
JPS5699414A
JPS5699414A JP244080A JP244080A JPS5699414A JP S5699414 A JPS5699414 A JP S5699414A JP 244080 A JP244080 A JP 244080A JP 244080 A JP244080 A JP 244080A JP S5699414 A JPS5699414 A JP S5699414A
Authority
JP
Japan
Prior art keywords
uracil
fluoro compound
antitumorigenic
agent
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP244080A
Other languages
Japanese (ja)
Other versions
JPS6312845B2 (en
Inventor
Norio Saimi
Setsuo Takeda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taiho Pharmaceutical Co Ltd
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Priority to JP244080A priority Critical patent/JPS5699414A/en
Publication of JPS5699414A publication Critical patent/JPS5699414A/en
Publication of JPS6312845B2 publication Critical patent/JPS6312845B2/ja
Granted legal-status Critical Current

Links

Abstract

PURPOSE: An antitumorigenic agent that is made by adding a uracil to a specific fluoro compound whereby the antitumorgenic activity of the fluoro compound is extremely increased and the toxicity becomes low.
CONSTITUTION: Ethyl 6-n-butoxy-5-fluorohexahydro-2,4-dioxopyrimidine-5-carboxylate (abbreviated to fluoro compound hereinafter) is combined with at least one selected from uracils consisting of uracil, thymine and thymidine to give the antitumorigenic agent. The amount of the uracil is preferably 0.5W100mol/mol of the fluoro compound. Although a uracil itself has no antitumorigenic activity, the combination with the fluoro compound markedly increase the effect of the compound. Further, the titled antitumorigenic agent scarcely develops toxicity.
COPYRIGHT: (C)1981,JPO&Japio
JP244080A 1980-01-11 1980-01-11 Antitumorigenic agent Granted JPS5699414A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP244080A JPS5699414A (en) 1980-01-11 1980-01-11 Antitumorigenic agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP244080A JPS5699414A (en) 1980-01-11 1980-01-11 Antitumorigenic agent

Publications (2)

Publication Number Publication Date
JPS5699414A true JPS5699414A (en) 1981-08-10
JPS6312845B2 JPS6312845B2 (en) 1988-03-23

Family

ID=11529324

Family Applications (1)

Application Number Title Priority Date Filing Date
JP244080A Granted JPS5699414A (en) 1980-01-11 1980-01-11 Antitumorigenic agent

Country Status (1)

Country Link
JP (1) JPS5699414A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4719213A (en) * 1977-04-05 1988-01-12 Taiho Pharmaceutical Company Limited Anti-cancer composition for delivering 5-fluorouracil

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4719213A (en) * 1977-04-05 1988-01-12 Taiho Pharmaceutical Company Limited Anti-cancer composition for delivering 5-fluorouracil

Also Published As

Publication number Publication date
JPS6312845B2 (en) 1988-03-23

Similar Documents

Publication Publication Date Title
JPS55111420A (en) Antitumorigenic agent
JPS5699414A (en) Antitumorigenic agent
JPS5414957A (en) Preparation of 3-acylamino-4-homoisotwistan
JPS5362935A (en) Word processor
JPS5677226A (en) Antitumorigenic agent
ES8201123A1 (en) Substituted benzonitriles and compositions for inhibiting viruses.
JPS5329938A (en) Carcinostatic agent
JPS5423132A (en) Analgesic composition
JPS5318540A (en) Alpha-chloroacetamides and their use
JPS53108179A (en) Highly water-resistant multiporous board
JPS53138316A (en) Modulating system
JPS5381497A (en) Stabilized sodium persulfate composition
JPS5289678A (en) Preparation of 1-(2-tetrahydrofuryl)-5-fluorouracil
JPS5683420A (en) Antineoplasmic composition
JPS52130906A (en) Stable solution of uracil derivative
JPS5435208A (en) Stabilization of prostaglandin and prostaglandin-ramily compound
JPS56145217A (en) Antitumor agent
JPS56110623A (en) Carcinostatic agent
JPS5325573A (en) Optical active 6-oxo-piperidineethanols and their preparation
JPS5564518A (en) Carcinostatic composition
JPS53124281A (en) Cis-8-(o-dimethylthiocarbamyl)-3,6,11-tri-methyl-2,6-methano-1,2,3,4,5,6 hexahydro-3-benzazocin
JPS53108988A (en) Preparation of 1-(2-tetrahydrofuryl)-5-fluorouracil
JPS53101333A (en) 3-acyloxymethyl-3,4:5,6-diepoxycyclohexane-1,2-diol and
ES8308927A1 (en) Lincomycin 3-(5'- ribonucleotides)
JPS53132541A (en) Optically active 2-alkyl-4-isopropenyl cyclohexanone and its preparation