JPS56145217A - Antitumor agent - Google Patents
Antitumor agentInfo
- Publication number
- JPS56145217A JPS56145217A JP4845980A JP4845980A JPS56145217A JP S56145217 A JPS56145217 A JP S56145217A JP 4845980 A JP4845980 A JP 4845980A JP 4845980 A JP4845980 A JP 4845980A JP S56145217 A JPS56145217 A JP S56145217A
- Authority
- JP
- Japan
- Prior art keywords
- fluorouracil
- antitumor agent
- effect
- formula
- active constituent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: To obtain an antitumor agent having a great effect of action with low toxicity, by using a specific 5-fluorouracil derivative as an active constituent.
CONSTITUTION: An antitumor agent prepared by using 1-(2,5-dihydro-2-furamyl)- 5-fluorouracil of the formula as an active constituent. The compound of the formula is a compound well known as a synthetic intermediate for 5-fluorouracil derivatives and has a greater tumor suppressing effect and longevous effect than those of other 5-fluorouracil derivatives, e.g. 1-(tetrahydro-2-furanyl)-5-fluorouracil. The acute toxicity LD50 is 380mg/kg in a mouse.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4845980A JPS56145217A (en) | 1980-04-11 | 1980-04-11 | Antitumor agent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4845980A JPS56145217A (en) | 1980-04-11 | 1980-04-11 | Antitumor agent |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56145217A true JPS56145217A (en) | 1981-11-11 |
JPS6334847B2 JPS6334847B2 (en) | 1988-07-12 |
Family
ID=12803938
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP4845980A Granted JPS56145217A (en) | 1980-04-11 | 1980-04-11 | Antitumor agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56145217A (en) |
-
1980
- 1980-04-11 JP JP4845980A patent/JPS56145217A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6334847B2 (en) | 1988-07-12 |
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