JPS5692871A - Isoquinolineacetic acid - Google Patents
Isoquinolineacetic acidInfo
- Publication number
- JPS5692871A JPS5692871A JP17706680A JP17706680A JPS5692871A JP S5692871 A JPS5692871 A JP S5692871A JP 17706680 A JP17706680 A JP 17706680A JP 17706680 A JP17706680 A JP 17706680A JP S5692871 A JPS5692871 A JP S5692871A
- Authority
- JP
- Japan
- Prior art keywords
- isoquinolineacetic acid
- isoquinolineacetic
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- CPPDVCCRUHPOSK-UHFFFAOYSA-N 2-isoquinolin-1-ylacetic acid Chemical compound C1=CC=C2C(CC(=O)O)=NC=CC2=C1 CPPDVCCRUHPOSK-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/86—Unsaturated compounds containing keto groups containing six-membered aromatic rings and other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/104,939 US4283539A (en) | 1979-12-18 | 1979-12-18 | Isoquinoline acetic acids |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5692871A true JPS5692871A (en) | 1981-07-27 |
JPS6210508B2 JPS6210508B2 (ja) | 1987-03-06 |
Family
ID=22303241
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP17706680A Granted JPS5692871A (en) | 1979-12-18 | 1980-12-15 | Isoquinolineacetic acid |
Country Status (7)
Country | Link |
---|---|
US (1) | US4283539A (ja) |
EP (1) | EP0030861B1 (ja) |
JP (1) | JPS5692871A (ja) |
DE (1) | DE3064453D1 (ja) |
DK (1) | DK149569C (ja) |
GR (1) | GR72804B (ja) |
IE (1) | IE50524B1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999018077A1 (fr) * | 1997-10-02 | 1999-04-15 | Eisai Co., Ltd. | Derives de pyridine condenses |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4761403A (en) * | 1986-04-09 | 1988-08-02 | Abbott Laboratories | Lipoxygenase inhibiting compounds |
CN1064306C (zh) * | 1994-12-06 | 2001-04-11 | Sig瑞士工业-协会 | 管形袋包装机的横向密封装置 |
GB9424842D0 (en) * | 1994-12-09 | 1995-02-08 | British Tech Group | Pharmaceutical compositions |
CN1205207C (zh) * | 1998-03-31 | 2005-06-08 | 药品发现学会公司 | 取代的吲哚链烷酸 |
TNSN99224A1 (fr) * | 1998-12-01 | 2005-11-10 | Inst For Pharm Discovery Inc | Methodes de reduction des niveaux de glucose et triglyceride en serum et pour suppression de l'antigenese utilisant les acides la indolealkanoique |
US7151102B2 (en) | 2000-10-30 | 2006-12-19 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
WO2002090334A1 (en) | 2001-05-08 | 2002-11-14 | Kudos Pharmaceuticals Limited | Isoquinolinone derivatives as parp inhibitors |
US7196085B2 (en) | 2002-04-30 | 2007-03-27 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
KR20050026002A (ko) * | 2002-07-26 | 2005-03-14 | 디 인스티튜트스 포 파마슈티컬 디스커버리, 엘엘씨 | 치환된 인돌알칸산 유도체 및 이를 함유하는 당뇨 합병증치료용 제형 |
WO2004054979A1 (ja) * | 2002-12-18 | 2004-07-01 | Takeda Pharmaceutical Company Limited | Jnk阻害剤 |
US7449464B2 (en) | 2003-03-12 | 2008-11-11 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
GB0305681D0 (en) | 2003-03-12 | 2003-04-16 | Kudos Pharm Ltd | Phthalazinone derivatives |
GB0419072D0 (en) | 2004-08-26 | 2004-09-29 | Kudos Pharm Ltd | Phthalazinone derivatives |
GB0521373D0 (en) | 2005-10-20 | 2005-11-30 | Kudos Pharm Ltd | Pthalazinone derivatives |
RU2010108008A (ru) | 2007-09-14 | 2011-10-20 | Астразенека Аб (Se) | Фталазиноновые производные |
US8183369B2 (en) | 2007-10-17 | 2012-05-22 | Kudos Pharmaceuticals Limited | 4- [3- (4-cyclopropanecarbonyl-piperazine-I-carbonyl) -4 -fluoro-benzyl] -2H-phthalaz in-1-one |
AR070221A1 (es) | 2008-01-23 | 2010-03-25 | Astrazeneca Ab | Derivados de ftalazinona inhibidores de polimerasas, composiciones farmaceuticas que los contienen y usos de los mismos para prevenir y/o tratar tumores cancerigenos,lesiones isquemicas y otras enfermedades asociadas. |
CN102238945B (zh) | 2008-10-07 | 2014-10-29 | 阿斯利康(英国)有限公司 | 药物制剂514 |
EP2586772A4 (en) * | 2010-06-23 | 2013-11-13 | Taisho Pharmaceutical Co Ltd | ISOQUINOLINE DERIVATIVE |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3821383A (en) * | 1972-07-10 | 1974-06-28 | Ayerst Mckenna & Harrison | Compositions for and a method of treating diabetic complications |
US4036964A (en) * | 1973-10-11 | 1977-07-19 | Beecham Group Limited | Isocarbostyril-3-carboxylic acid derivatives for the prophylaxis of asthma, hayfever and rhinitis |
-
1979
- 1979-12-18 US US06/104,939 patent/US4283539A/en not_active Expired - Lifetime
-
1980
- 1980-12-15 EP EP80304517A patent/EP0030861B1/en not_active Expired
- 1980-12-15 JP JP17706680A patent/JPS5692871A/ja active Granted
- 1980-12-15 DE DE8080304517T patent/DE3064453D1/de not_active Expired
- 1980-12-16 GR GR63666A patent/GR72804B/el unknown
- 1980-12-17 DK DK536480A patent/DK149569C/da not_active IP Right Cessation
- 1980-12-17 IE IE2661/80A patent/IE50524B1/en unknown
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999018077A1 (fr) * | 1997-10-02 | 1999-04-15 | Eisai Co., Ltd. | Derives de pyridine condenses |
US6790844B2 (en) | 1997-10-02 | 2004-09-14 | Eisai Co., Ltd | Certain 1,3-disubstituted isoquinoline derivatives |
US6875761B2 (en) | 1997-10-02 | 2005-04-05 | Eisai Co., Ltd. | Certain 1,3-disubstituted isoquinoline derivatives |
Also Published As
Publication number | Publication date |
---|---|
IE50524B1 (en) | 1986-04-30 |
IE802661L (en) | 1981-06-18 |
DK149569B (da) | 1986-07-28 |
DK536480A (da) | 1981-06-19 |
GR72804B (ja) | 1983-12-05 |
EP0030861A3 (en) | 1981-09-23 |
DK149569C (da) | 1987-02-02 |
JPS6210508B2 (ja) | 1987-03-06 |
EP0030861B1 (en) | 1983-07-27 |
DE3064453D1 (en) | 1983-09-01 |
EP0030861A2 (en) | 1981-06-24 |
US4283539A (en) | 1981-08-11 |
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