JPS5678597A - Preparation of 7alpha,12alpha-dihydroxy-3-keto-5beta-cholanic acid - Google Patents
Preparation of 7alpha,12alpha-dihydroxy-3-keto-5beta-cholanic acidInfo
- Publication number
- JPS5678597A JPS5678597A JP15470879A JP15470879A JPS5678597A JP S5678597 A JPS5678597 A JP S5678597A JP 15470879 A JP15470879 A JP 15470879A JP 15470879 A JP15470879 A JP 15470879A JP S5678597 A JPS5678597 A JP S5678597A
- Authority
- JP
- Japan
- Prior art keywords
- salt
- keto
- dihydroxy
- acid
- cholic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PURPOSE: To obtain the titled substance in high yield and in a short time, by cultivating a bacterium which belongs to the genus Arthrobacter and has the ability to produce the titled substance and/or a salt thereof in the presence of a salt of cholic acid as a substrate.
CONSTITUTION: Arthrobacter-CA-35 strain (FERM-P No.5145) or a variant thereof is cultivated in an ordinary culture medium containing about 10W500g/l salt of cholic acid as a substrate by the shaking culture or spinner culture method with aeration. An insoluble component, e.g. microbial cell, is removed from the culture fluid, and hydrochloric acid is added to a filtrate or a supernatant liquid to precipitate a resultant salt derivative of cholic acid, e.g. 7α,12α-dihydroxy-3-keto-5β- cholanic acid.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15470879A JPS5910199B2 (en) | 1979-11-28 | 1979-11-28 | Method for producing 7α,12α-dihydroxy-3-keto-5β-cholanic acid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15470879A JPS5910199B2 (en) | 1979-11-28 | 1979-11-28 | Method for producing 7α,12α-dihydroxy-3-keto-5β-cholanic acid |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5678597A true JPS5678597A (en) | 1981-06-27 |
JPS5910199B2 JPS5910199B2 (en) | 1984-03-07 |
Family
ID=15590213
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15470879A Expired JPS5910199B2 (en) | 1979-11-28 | 1979-11-28 | Method for producing 7α,12α-dihydroxy-3-keto-5β-cholanic acid |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5910199B2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6372943U (en) * | 1986-10-30 | 1988-05-16 |
-
1979
- 1979-11-28 JP JP15470879A patent/JPS5910199B2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS5910199B2 (en) | 1984-03-07 |
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