JPS5678597A - Preparation of 7alpha,12alpha-dihydroxy-3-keto-5beta-cholanic acid - Google Patents

Preparation of 7alpha,12alpha-dihydroxy-3-keto-5beta-cholanic acid

Info

Publication number
JPS5678597A
JPS5678597A JP15470879A JP15470879A JPS5678597A JP S5678597 A JPS5678597 A JP S5678597A JP 15470879 A JP15470879 A JP 15470879A JP 15470879 A JP15470879 A JP 15470879A JP S5678597 A JPS5678597 A JP S5678597A
Authority
JP
Japan
Prior art keywords
salt
keto
dihydroxy
acid
cholic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP15470879A
Other languages
Japanese (ja)
Other versions
JPS5910199B2 (en
Inventor
Masao Tsuji
Yoshihiro Ichihara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kuraray Co Ltd
Original Assignee
Kuraray Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kuraray Co Ltd filed Critical Kuraray Co Ltd
Priority to JP15470879A priority Critical patent/JPS5910199B2/en
Publication of JPS5678597A publication Critical patent/JPS5678597A/en
Publication of JPS5910199B2 publication Critical patent/JPS5910199B2/en
Expired legal-status Critical Current

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PURPOSE: To obtain the titled substance in high yield and in a short time, by cultivating a bacterium which belongs to the genus Arthrobacter and has the ability to produce the titled substance and/or a salt thereof in the presence of a salt of cholic acid as a substrate.
CONSTITUTION: Arthrobacter-CA-35 strain (FERM-P No.5145) or a variant thereof is cultivated in an ordinary culture medium containing about 10W500g/l salt of cholic acid as a substrate by the shaking culture or spinner culture method with aeration. An insoluble component, e.g. microbial cell, is removed from the culture fluid, and hydrochloric acid is added to a filtrate or a supernatant liquid to precipitate a resultant salt derivative of cholic acid, e.g. 7α,12α-dihydroxy-3-keto-5β- cholanic acid.
COPYRIGHT: (C)1981,JPO&Japio
JP15470879A 1979-11-28 1979-11-28 Method for producing 7α,12α-dihydroxy-3-keto-5β-cholanic acid Expired JPS5910199B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP15470879A JPS5910199B2 (en) 1979-11-28 1979-11-28 Method for producing 7α,12α-dihydroxy-3-keto-5β-cholanic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15470879A JPS5910199B2 (en) 1979-11-28 1979-11-28 Method for producing 7α,12α-dihydroxy-3-keto-5β-cholanic acid

Publications (2)

Publication Number Publication Date
JPS5678597A true JPS5678597A (en) 1981-06-27
JPS5910199B2 JPS5910199B2 (en) 1984-03-07

Family

ID=15590213

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15470879A Expired JPS5910199B2 (en) 1979-11-28 1979-11-28 Method for producing 7α,12α-dihydroxy-3-keto-5β-cholanic acid

Country Status (1)

Country Link
JP (1) JPS5910199B2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6372943U (en) * 1986-10-30 1988-05-16

Also Published As

Publication number Publication date
JPS5910199B2 (en) 1984-03-07

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