JPS5665828A - Antitumor agent - Google Patents
Antitumor agentInfo
- Publication number
- JPS5665828A JPS5665828A JP14215279A JP14215279A JPS5665828A JP S5665828 A JPS5665828 A JP S5665828A JP 14215279 A JP14215279 A JP 14215279A JP 14215279 A JP14215279 A JP 14215279A JP S5665828 A JPS5665828 A JP S5665828A
- Authority
- JP
- Japan
- Prior art keywords
- agent
- antibody
- purity
- tumor
- antitumor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002246 antineoplastic agent Substances 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 5
- 229940100198 alkylating agent Drugs 0.000 abstract 3
- 239000002168 alkylating agent Substances 0.000 abstract 3
- 239000000427 antigen Substances 0.000 abstract 3
- 102000036639 antigens Human genes 0.000 abstract 3
- 108091007433 antigens Proteins 0.000 abstract 3
- 230000000259 anti-tumor effect Effects 0.000 abstract 2
- 201000011510 cancer Diseases 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- IDPUKCWIGUEADI-UHFFFAOYSA-N 5-[bis(2-chloroethyl)amino]uracil Chemical compound ClCCN(CCCl)C1=CNC(=O)NC1=O IDPUKCWIGUEADI-UHFFFAOYSA-N 0.000 abstract 1
- 108060003951 Immunoglobulin Proteins 0.000 abstract 1
- 208000007093 Leukemia L1210 Diseases 0.000 abstract 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 abstract 1
- SGDBTWWWUNNDEQ-UHFFFAOYSA-N Merphalan Chemical compound OC(=O)C(N)CC1=CC=C(N(CCCl)CCCl)C=C1 SGDBTWWWUNNDEQ-UHFFFAOYSA-N 0.000 abstract 1
- 208000006268 Sarcoma 180 Diseases 0.000 abstract 1
- 238000001042 affinity chromatography Methods 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 229960004630 chlorambucil Drugs 0.000 abstract 1
- JCKYGMPEJWAADB-UHFFFAOYSA-N chlorambucil Chemical compound OC(=O)CCCC1=CC=C(N(CCCl)CCCl)C=C1 JCKYGMPEJWAADB-UHFFFAOYSA-N 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 102000018358 immunoglobulin Human genes 0.000 abstract 1
- 201000005202 lung cancer Diseases 0.000 abstract 1
- 208000020816 lung neoplasm Diseases 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
- 229960001055 uracil mustard Drugs 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14215279A JPS5665828A (en) | 1979-11-02 | 1979-11-02 | Antitumor agent |
US06/103,474 US4315851A (en) | 1978-12-29 | 1979-12-14 | Pharmaceutical composition having antitumor activity |
SE7910483A SE7910483L (sv) | 1978-12-29 | 1979-12-19 | Farmaceutisk komposition med tumorhemmande effekt |
PH23447A PH16902A (en) | 1978-12-29 | 1979-12-20 | Pharmaceutical composition having anti-tumor activity |
GB7944494A GB2038836B (en) | 1978-12-29 | 1979-12-28 | Antitumour substance |
FR797932054A FR2445149B1 (fr) | 1978-12-29 | 1979-12-28 | Composition pharmaceutique ayant une activite antitumorale |
CH11501/79A CH655010A5 (de) | 1978-12-29 | 1979-12-28 | Pharmazeutischer wirkstoff mit antitumoraktivitaet. |
DE2952690A DE2952690C2 (de) | 1978-12-29 | 1979-12-29 | Antitumorsubstanz, Verfahren zu ihrer Herstellung und diese enthaltendes pharmazeutisches Mittel |
IT28464/79A IT1127324B (it) | 1978-12-29 | 1979-12-31 | Composizione farmaceutica avente attivita' antitumorale |
US06/321,486 US4401592A (en) | 1978-12-29 | 1981-11-16 | Pharmaceutical composition having antitumor activity |
SE8406510A SE8406510D0 (sv) | 1978-12-29 | 1984-12-20 | Farmaceutisk komposition med tumorhemmande effekt |
SE8406511A SE8406511D0 (sv) | 1978-12-29 | 1984-12-20 | Farmaceutisk komposition med tumorhemmande effekt |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14215279A JPS5665828A (en) | 1979-11-02 | 1979-11-02 | Antitumor agent |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5665828A true JPS5665828A (en) | 1981-06-03 |
JPS6256136B2 JPS6256136B2 (enrdf_load_stackoverflow) | 1987-11-24 |
Family
ID=15308563
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP14215279A Granted JPS5665828A (en) | 1978-12-29 | 1979-11-02 | Antitumor agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5665828A (enrdf_load_stackoverflow) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58118520A (ja) * | 1982-01-09 | 1983-07-14 | Hidematsu Hirai | 抗腫瘍性蛋白複合体およびその製造法 |
JPS62142123A (ja) * | 1983-04-08 | 1987-06-25 | Kureha Chem Ind Co Ltd | ヒト免疫グロブリン結合抗腫瘍剤 |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0470125U (enrdf_load_stackoverflow) * | 1990-10-25 | 1992-06-22 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4962194A (enrdf_load_stackoverflow) * | 1972-05-10 | 1974-06-17 | ||
JPS5161640A (en) * | 1974-09-20 | 1976-05-28 | Searle & Co | Koshuyozaino seizoho |
JPS51144723A (en) * | 1975-05-27 | 1976-12-13 | Yeda Res & Dev | Antiitumor agent |
JPS5592325A (en) * | 1978-12-29 | 1980-07-12 | Kureha Chem Ind Co Ltd | Antitumor agent and its preparation |
-
1979
- 1979-11-02 JP JP14215279A patent/JPS5665828A/ja active Granted
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4962194A (enrdf_load_stackoverflow) * | 1972-05-10 | 1974-06-17 | ||
JPS5161640A (en) * | 1974-09-20 | 1976-05-28 | Searle & Co | Koshuyozaino seizoho |
JPS51144723A (en) * | 1975-05-27 | 1976-12-13 | Yeda Res & Dev | Antiitumor agent |
JPS5592325A (en) * | 1978-12-29 | 1980-07-12 | Kureha Chem Ind Co Ltd | Antitumor agent and its preparation |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58118520A (ja) * | 1982-01-09 | 1983-07-14 | Hidematsu Hirai | 抗腫瘍性蛋白複合体およびその製造法 |
JPS62142123A (ja) * | 1983-04-08 | 1987-06-25 | Kureha Chem Ind Co Ltd | ヒト免疫グロブリン結合抗腫瘍剤 |
Also Published As
Publication number | Publication date |
---|---|
JPS6256136B2 (enrdf_load_stackoverflow) | 1987-11-24 |
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