JPS5161640A - Koshuyozaino seizoho - Google Patents

Koshuyozaino seizoho

Info

Publication number
JPS5161640A
JPS5161640A JP50113541A JP11354175A JPS5161640A JP S5161640 A JPS5161640 A JP S5161640A JP 50113541 A JP50113541 A JP 50113541A JP 11354175 A JP11354175 A JP 11354175A JP S5161640 A JPS5161640 A JP S5161640A
Authority
JP
Japan
Prior art keywords
koshuyozaino
seizoho
koshuyozaino seizoho
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP50113541A
Other languages
Japanese (ja)
Inventor
Arin Ruisu Deebisu Deebitsudo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle and Co Ltd
GD Searle LLC
Original Assignee
GD Searle and Co Ltd
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle and Co Ltd, GD Searle LLC filed Critical GD Searle and Co Ltd
Publication of JPS5161640A publication Critical patent/JPS5161640A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6889—Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Metal Rolling (AREA)
JP50113541A 1974-09-20 1975-09-19 Koshuyozaino seizoho Pending JPS5161640A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB41037/74A GB1509707A (en) 1974-09-20 1974-09-20 Immunological compounds

Publications (1)

Publication Number Publication Date
JPS5161640A true JPS5161640A (en) 1976-05-28

Family

ID=10417824

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50113541A Pending JPS5161640A (en) 1974-09-20 1975-09-19 Koshuyozaino seizoho

Country Status (7)

Country Link
JP (1) JPS5161640A (en)
DE (1) DE2541931A1 (en)
DK (1) DK141773B (en)
FR (1) FR2285145A1 (en)
GB (1) GB1509707A (en)
NL (1) NL7511089A (en)
SE (1) SE7510505L (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS539324A (en) * 1976-05-13 1978-01-27 Procter & Gamble Treating composition
JPS54132503A (en) * 1978-04-07 1979-10-15 Kayaku Antibiotic Research Co Immune globulin combined neocarcinostatin
JPS5592325A (en) * 1978-12-29 1980-07-12 Kureha Chem Ind Co Ltd Antitumor agent and its preparation
JPS5665828A (en) * 1979-11-02 1981-06-03 Kureha Chem Ind Co Ltd Antitumor agent
JPS5665829A (en) * 1979-11-02 1981-06-03 Kureha Chem Ind Co Ltd Antitumor agent
JPS5718624A (en) * 1980-03-31 1982-01-30 Inst Int Pathologie Cellulaire Drug and manufacture
JPS58118520A (en) * 1982-01-09 1983-07-14 Hidematsu Hirai Antitumor proteinic complex and preparation thereof
JPS59186924A (en) * 1983-04-08 1984-10-23 Kureha Chem Ind Co Ltd Antitumor agent bonded with human immunoglobulin
WO1987004171A1 (en) * 1985-12-27 1987-07-16 Teijin Limited Process for preparing antibody complex
JPS63238100A (en) * 1987-03-26 1988-10-04 Teijin Ltd Production of antibody complex

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4315851A (en) 1978-12-29 1982-02-16 Kureha Kagaku Kogyo Kabushiki Kaisha Pharmaceutical composition having antitumor activity
GB2148299B (en) * 1983-09-01 1988-01-06 Hybritech Inc Antibody compositions of therapeutic agents having an extended serum half-life
DE3513572A1 (en) * 1985-04-16 1986-10-16 Karl Prof. Dr.med. 7302 Ostfildern Theurer Preparation of products for specifically influencing the humoral and cellular immune response
US5773435A (en) * 1987-08-04 1998-06-30 Bristol-Myers Squibb Company Prodrugs for β-lactamase and uses thereof
AU649275B2 (en) * 1990-11-06 1994-05-19 Bristol-Myers Squibb Company Prodrugs for beta-lactamase and uses thereof
DE4122210C2 (en) * 1991-07-04 1999-04-01 Deutsches Krebsforsch Tumor-active compound-serum albumin conjugates, process for their preparation and their use

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6221767B2 (en) * 1976-05-13 1987-05-14 Procter & Gamble
JPS539324A (en) * 1976-05-13 1978-01-27 Procter & Gamble Treating composition
JPS54132503A (en) * 1978-04-07 1979-10-15 Kayaku Antibiotic Research Co Immune globulin combined neocarcinostatin
JPS5592325A (en) * 1978-12-29 1980-07-12 Kureha Chem Ind Co Ltd Antitumor agent and its preparation
JPS6254086B2 (en) * 1978-12-29 1987-11-13 Kureha Chemical Ind Co Ltd
JPS5665829A (en) * 1979-11-02 1981-06-03 Kureha Chem Ind Co Ltd Antitumor agent
JPS5665828A (en) * 1979-11-02 1981-06-03 Kureha Chem Ind Co Ltd Antitumor agent
JPS6256136B2 (en) * 1979-11-02 1987-11-24 Kureha Chemical Ind Co Ltd
JPS6256137B2 (en) * 1979-11-02 1987-11-24 Kureha Chemical Ind Co Ltd
JPS5718624A (en) * 1980-03-31 1982-01-30 Inst Int Pathologie Cellulaire Drug and manufacture
JPH049771B2 (en) * 1980-03-31 1992-02-21
JPS58118520A (en) * 1982-01-09 1983-07-14 Hidematsu Hirai Antitumor proteinic complex and preparation thereof
JPS59186924A (en) * 1983-04-08 1984-10-23 Kureha Chem Ind Co Ltd Antitumor agent bonded with human immunoglobulin
JPS6330289B2 (en) * 1983-04-08 1988-06-17 Kureha Chemical Ind Co Ltd
WO1987004171A1 (en) * 1985-12-27 1987-07-16 Teijin Limited Process for preparing antibody complex
JPS63238100A (en) * 1987-03-26 1988-10-04 Teijin Ltd Production of antibody complex

Also Published As

Publication number Publication date
DK141773C (en) 1980-11-03
FR2285145B1 (en) 1980-05-30
NL7511089A (en) 1976-03-23
DK141773B (en) 1980-06-16
GB1509707A (en) 1978-05-04
FR2285145A1 (en) 1976-04-16
DE2541931A1 (en) 1976-04-01
DK422475A (en) 1976-03-21
SE7510505L (en) 1976-03-22

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