JPS5655399A - Deformyltylosin derivative - Google Patents
Deformyltylosin derivativeInfo
- Publication number
- JPS5655399A JPS5655399A JP12026979A JP12026979A JPS5655399A JP S5655399 A JPS5655399 A JP S5655399A JP 12026979 A JP12026979 A JP 12026979A JP 12026979 A JP12026979 A JP 12026979A JP S5655399 A JPS5655399 A JP S5655399A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- group
- alkanoyl
- acetyl
- dissolving
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- DYQLJLSOTKRQCO-DIYLDRNKSA-N (4r,5s,6s,7s,9r,11e,13e,15r,16r)-6-[(2r,3r,4r,5s,6r)-5-[(2s,4r,5s,6s)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-15-[[(2r,3r,4r,5r,6r)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-5 Chemical class O([C@@H]1[C@@H](C)O[C@H]([C@@H]([C@H]1N(C)C)O)O[C@@H]1[C@@H](C)[C@H](O)CC(=O)O[C@@H]([C@H](/C=C(\C)/C=C/C(=O)[C@H](C)C[C@@H]1C)CO[C@H]1[C@@H]([C@H](OC)[C@H](O)[C@@H](C)O1)OC)CC)[C@H]1C[C@@](C)(O)[C@@H](O)[C@H](C)O1 DYQLJLSOTKRQCO-DIYLDRNKSA-N 0.000 title 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 4
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 229930194936 Tylosin Natural products 0.000 abstract 1
- 239000004182 Tylosin Substances 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 239000012295 chemical reaction liquid Substances 0.000 abstract 1
- 238000004440 column chromatography Methods 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 239000000706 filtrate Substances 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000003120 macrolide antibiotic agent Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- QBERHIJABFXGRZ-UHFFFAOYSA-M rhodium;triphenylphosphane;chloride Chemical compound [Cl-].[Rh].C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1.C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1.C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1 QBERHIJABFXGRZ-UHFFFAOYSA-M 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- WBPYTXDJUQJLPQ-VMXQISHHSA-N tylosin Chemical compound O([C@@H]1[C@@H](C)O[C@H]([C@@H]([C@H]1N(C)C)O)O[C@@H]1[C@@H](C)[C@H](O)CC(=O)O[C@@H]([C@H](/C=C(\C)/C=C/C(=O)[C@H](C)C[C@@H]1CC=O)CO[C@H]1[C@@H]([C@H](OC)[C@H](O)[C@@H](C)O1)OC)CC)[C@H]1C[C@@](C)(O)[C@@H](O)[C@H](C)O1 WBPYTXDJUQJLPQ-VMXQISHHSA-N 0.000 abstract 1
- 229960004059 tylosin Drugs 0.000 abstract 1
- 235000019375 tylosin Nutrition 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12026979A JPS5655399A (en) | 1979-09-19 | 1979-09-19 | Deformyltylosin derivative |
| NL8004922A NL8004922A (nl) | 1979-09-19 | 1980-08-29 | Deformyltylosinederivaten. |
| DE19803033032 DE3033032A1 (de) | 1979-09-19 | 1980-09-02 | Deformyltylosinderivate |
| US06/184,375 US4345069A (en) | 1979-09-19 | 1980-09-05 | Deformyltylosin derivatives |
| GB8029019A GB2058765B (en) | 1979-09-19 | 1980-09-09 | Deformyltylosin derivatives |
| FR8019987A FR2465747A1 (fr) | 1979-09-19 | 1980-09-17 | Derives de deformyltylosine utiles notamment comme antibiotiques |
| CH699780A CH645650A5 (de) | 1979-09-19 | 1980-09-18 | Deformyltylosinderivate. |
| IT24738/80A IT1141057B (it) | 1979-09-19 | 1980-09-18 | Derivati di deformiltilosina e loro preparazione |
| ES495214A ES495214A0 (es) | 1979-09-19 | 1980-09-19 | Procedimiento para la obtencion de nuevos derivados defor- miltilosinos |
| ES503606A ES503606A0 (es) | 1979-09-19 | 1981-07-01 | Procedimiento de produccion de 20-deoxo-4-semicaroriltilomiao de una sal de la misma. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12026979A JPS5655399A (en) | 1979-09-19 | 1979-09-19 | Deformyltylosin derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5655399A true JPS5655399A (en) | 1981-05-15 |
| JPS6155920B2 JPS6155920B2 (en, 2012) | 1986-11-29 |
Family
ID=14782030
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP12026979A Granted JPS5655399A (en) | 1979-09-19 | 1979-09-19 | Deformyltylosin derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5655399A (en, 2012) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3222268A1 (de) * | 1981-06-23 | 1983-01-13 | Toyo Jozo K.K., Tagata, Shizuoka | 19-deformyldeoxydesmycosin |
| JPS5973599A (ja) * | 1982-09-13 | 1984-04-25 | イーライ・リリー・アンド・カンバニー | Ｃ−２０−修飾マクロライド誘導体 |
-
1979
- 1979-09-19 JP JP12026979A patent/JPS5655399A/ja active Granted
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3222268A1 (de) * | 1981-06-23 | 1983-01-13 | Toyo Jozo K.K., Tagata, Shizuoka | 19-deformyldeoxydesmycosin |
| JPS5973599A (ja) * | 1982-09-13 | 1984-04-25 | イーライ・リリー・アンド・カンバニー | Ｃ−２０−修飾マクロライド誘導体 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6155920B2 (en, 2012) | 1986-11-29 |
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