JPS5655369A - Pyridinemethanol derivative - Google Patents
Pyridinemethanol derivativeInfo
- Publication number
- JPS5655369A JPS5655369A JP13230779A JP13230779A JPS5655369A JP S5655369 A JPS5655369 A JP S5655369A JP 13230779 A JP13230779 A JP 13230779A JP 13230779 A JP13230779 A JP 13230779A JP S5655369 A JPS5655369 A JP S5655369A
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- formula
- compound
- day
- sympathtic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- SHNUBALDGXWUJI-UHFFFAOYSA-N pyridin-2-ylmethanol Chemical class OCC1=CC=CC=N1 SHNUBALDGXWUJI-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000001953 Hypotension Diseases 0.000 abstract 1
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 230000001407 anti-thrombic effect Effects 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000005160 aryl oxy alkyl group Chemical group 0.000 abstract 1
- 102000012740 beta Adrenergic Receptors Human genes 0.000 abstract 1
- 108010079452 beta Adrenergic Receptors Proteins 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 230000001965 increasing effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13230779A JPS5655369A (en) | 1979-10-12 | 1979-10-12 | Pyridinemethanol derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13230779A JPS5655369A (en) | 1979-10-12 | 1979-10-12 | Pyridinemethanol derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5655369A true JPS5655369A (en) | 1981-05-15 |
| JPS6130668B2 JPS6130668B2 (en, 2012) | 1986-07-15 |
Family
ID=15078238
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP13230779A Granted JPS5655369A (en) | 1979-10-12 | 1979-10-12 | Pyridinemethanol derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5655369A (en, 2012) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62263155A (ja) * | 1986-05-06 | 1987-11-16 | バイエル・アクチエンゲゼルシヤフト | 動物の生産促進用ヘテロアリ−ルエチルアミンの使用、ヘテロアリ−ルエチルアミンおよびその製造方法 |
| US5714506A (en) * | 1995-10-24 | 1998-02-03 | Merck & Co., Inc. | Selective β3 agonists for the treatment of diabetes and obesity |
| AU2018332501B2 (en) * | 2017-09-13 | 2023-09-21 | Atrogi Ab | Heteroaryl substituted beta-hydroxyethylamines for use in treating hyperglycaemia |
| US12280023B2 (en) | 2017-09-13 | 2025-04-22 | Atrogi Ab | Fluorophenyl beta-hydroxyethylamines and their use in the treatment of hyperglycaemia |
| US12378216B2 (en) | 2019-03-20 | 2025-08-05 | Atrogi Ab | Heteroaryl(heterocyclyl)methanol compounds useful in the treatment of hyperglycaemia |
-
1979
- 1979-10-12 JP JP13230779A patent/JPS5655369A/ja active Granted
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62263155A (ja) * | 1986-05-06 | 1987-11-16 | バイエル・アクチエンゲゼルシヤフト | 動物の生産促進用ヘテロアリ−ルエチルアミンの使用、ヘテロアリ−ルエチルアミンおよびその製造方法 |
| US5714506A (en) * | 1995-10-24 | 1998-02-03 | Merck & Co., Inc. | Selective β3 agonists for the treatment of diabetes and obesity |
| AU2018332501B2 (en) * | 2017-09-13 | 2023-09-21 | Atrogi Ab | Heteroaryl substituted beta-hydroxyethylamines for use in treating hyperglycaemia |
| US12036210B2 (en) | 2017-09-13 | 2024-07-16 | Atrogi Ab | Heteroaryl substituted beta-hydroxyethylamines for use in treating hyperglycaemia |
| US12280023B2 (en) | 2017-09-13 | 2025-04-22 | Atrogi Ab | Fluorophenyl beta-hydroxyethylamines and their use in the treatment of hyperglycaemia |
| US12378216B2 (en) | 2019-03-20 | 2025-08-05 | Atrogi Ab | Heteroaryl(heterocyclyl)methanol compounds useful in the treatment of hyperglycaemia |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6130668B2 (en, 2012) | 1986-07-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IE892129L (en) | Chemical compounds | |
| ZA8410021B (en) | 11beta-arylestradienes,their production,and pharmaceutical preparations containing same | |
| NO170280C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive sulfamatderivater | |
| ATE79376T1 (de) | Dithioacetal-verbindungen, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen. | |
| ES8206511A1 (es) | Procedimiento para la preparacion de derivados de isoquino- leina | |
| IE872658L (en) | Tetrahydroquinoline derivatives, a process for their preparation, their use and pharmaceutical formulations containing them | |
| NO882334L (no) | Fremgangsmaate for fremstilling av terapeutisk aktive alkansulfonanilid-derivater. | |
| ATE12641T1 (de) | Azepinindole, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen. | |
| DK511383D0 (da) | Fremgangsmade til fremstilling af piperidindionderivater,der beskytter hjertemuskulaturen med en antiarythmisk aktivitet | |
| JPS5655369A (en) | Pyridinemethanol derivative | |
| ES8701189A1 (es) | Procedimiento para preparar derivados s(carbamoil-fenilsele-nicos) de mercaptanos | |
| ES8303397A1 (es) | Un procedimiento para la preparacion de nuevos derivados de quinoleinetanol o quinoleinpropanol utiles como medicamentos | |
| GB1465025A (en) | Substituted phenylisothioureas a process for their preparation and their use as medicaments | |
| EP0299076A4 (en) | 5-hydroxyindole-3-carboxamide compound and medicinal use thereof | |
| DE3880564D1 (de) | Arzneimittel zur behandlung von herzinsuffizienz. | |
| GR3001468T3 (en) | 5-aminoalkyl-beta-carboline derivatives, their preparation and their use as medicaments | |
| SE9203824L (sv) | Bensofuranylimidazol-derivat, foerfarande foer framstaellning daerav och terapeutiska kompositioner innehaallande desamma | |
| JPS57131777A (en) | Preparation of piperazine derivative | |
| ES8605799A1 (es) | Procedimiento para la fabricacion de nuevos compuestos cinamoicos | |
| DK644487A (da) | Farmaceutisk praeparat indeholdende en 2-oxo-imidazolidinforbindelse | |
| FR2386524A1 (fr) | Amino-4 chloro-5 methoxy-2 n-(n-ethyl methyl-2 pyrrolidino)benzenesulfonamide, procede de preparation et medicaments le contenant | |
| GB1471237A (en) | Basically substituted benzenesulphonamides and process for preparing them | |
| ES8104265A1 (es) | Un procedimiento para la preparacion de nuevas bencenosulfi-namidas | |
| ES8606325A1 (es) | Procedimiento para preparar compuestos de 3-amino-2,3-dihi- dro-1-benzoxepina | |
| DE3782229D1 (de) | Verwendung von 2-oxo-imidazolidin-derivaten zur behandlung von nierenkrankheiten. |