JPS5655369A - Pyridinemethanol derivative - Google Patents

Pyridinemethanol derivative

Info

Publication number
JPS5655369A
JPS5655369A JP13230779A JP13230779A JPS5655369A JP S5655369 A JPS5655369 A JP S5655369A JP 13230779 A JP13230779 A JP 13230779A JP 13230779 A JP13230779 A JP 13230779A JP S5655369 A JPS5655369 A JP S5655369A
Authority
JP
Japan
Prior art keywords
alkyl
formula
compound
day
sympathtic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP13230779A
Other languages
Japanese (ja)
Other versions
JPS6130668B2 (en
Inventor
Kazuhiko Araki
Eiboku Ao
Tomio Muro
Akira Nakanishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Welfide Corp
Original Assignee
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welfide Corp filed Critical Welfide Corp
Priority to JP13230779A priority Critical patent/JPS5655369A/en
Publication of JPS5655369A publication Critical patent/JPS5655369A/en
Publication of JPS6130668B2 publication Critical patent/JPS6130668B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound of formula I (R is alkyl, alkenyl, alkynyl, cycloalkyl, etc.; R<1> and R<2> are H or alkyl; R<3> is 1-20C alkyl, aralkyl, aryloxyalkyl, etc.; R<2> ?and R<3> together may form a heterocyclic ring with the adjacent N; X is -0-, -S-, ?-SO-, etc.; m is O or 1) or its salt. EXAMPLE:1-(2-Isopropylthio-3-pyridyl)-2-n-octylaminopropanol.1/2 oxalate. USE:Pharmaceuticals having brain blood stream increasing, vasodilating, antithrombic, cholesterol level lowering, hypotensive, sympathtic beta-receptor blocking actions. Does: 10-1,500mg/kg wt./day by oral administration. One to several times a day. PROCESS:The compound of formula I is prepared by reducing an aminoketone compound of formula II (R<4> is R<2> or an amino-protecting group eliminable by hydrolysis or hydrogenation decomposition).
JP13230779A 1979-10-12 1979-10-12 Pyridinemethanol derivative Granted JPS5655369A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP13230779A JPS5655369A (en) 1979-10-12 1979-10-12 Pyridinemethanol derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13230779A JPS5655369A (en) 1979-10-12 1979-10-12 Pyridinemethanol derivative

Publications (2)

Publication Number Publication Date
JPS5655369A true JPS5655369A (en) 1981-05-15
JPS6130668B2 JPS6130668B2 (en) 1986-07-15

Family

ID=15078238

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13230779A Granted JPS5655369A (en) 1979-10-12 1979-10-12 Pyridinemethanol derivative

Country Status (1)

Country Link
JP (1) JPS5655369A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62263155A (en) * 1986-05-06 1987-11-16 バイエル・アクチエンゲゼルシヤフト Use of heteroarylethylamine for animal growth promotion, heteroarylethylamine and manufacture
US5714506A (en) * 1995-10-24 1998-02-03 Merck & Co., Inc. Selective β3 agonists for the treatment of diabetes and obesity
AU2018332501B2 (en) * 2017-09-13 2023-09-21 Atrogi Ab Heteroaryl substituted beta-hydroxyethylamines for use in treating hyperglycaemia

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62263155A (en) * 1986-05-06 1987-11-16 バイエル・アクチエンゲゼルシヤフト Use of heteroarylethylamine for animal growth promotion, heteroarylethylamine and manufacture
US5714506A (en) * 1995-10-24 1998-02-03 Merck & Co., Inc. Selective β3 agonists for the treatment of diabetes and obesity
AU2018332501B2 (en) * 2017-09-13 2023-09-21 Atrogi Ab Heteroaryl substituted beta-hydroxyethylamines for use in treating hyperglycaemia
US12036210B2 (en) 2017-09-13 2024-07-16 Atrogi Ab Heteroaryl substituted beta-hydroxyethylamines for use in treating hyperglycaemia

Also Published As

Publication number Publication date
JPS6130668B2 (en) 1986-07-15

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