JPS5655358A - Preparation of isopropylaminopropanol - Google Patents
Preparation of isopropylaminopropanolInfo
- Publication number
- JPS5655358A JPS5655358A JP13178379A JP13178379A JPS5655358A JP S5655358 A JPS5655358 A JP S5655358A JP 13178379 A JP13178379 A JP 13178379A JP 13178379 A JP13178379 A JP 13178379A JP S5655358 A JPS5655358 A JP S5655358A
- Authority
- JP
- Japan
- Prior art keywords
- compound shown
- formula
- agent
- reacted
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
PURPOSE: To obtain the titled compound through a simple method useful as a β- adrenergic neuronal blocking agent, etc. etc., by reacting a specific isopropylaminopropanol derivative with an alcohol in the presence of a condensation agent.
CONSTITUTION: A compound shown by the formula I (R is H or alkyl) is reacted with a compound shown by the formula II (R1 is saturated or unsaturated aliphatic hydrocarbon), to give a compound shown by the formula III or its salt. The reaction is carried out in the presence of an alkali cendensation agent at room temperature to 100°C. The compound shown by the formula III, e.g., 1-isopropylamino-2-hydroxy-3- (2-allyloxyphenoxy)-propane is effective as a remedy for breast pang, arrhythmia, etc. The compound shown by the formula I, for example, is obtained readily by reacting a compound shown by the formula V with a compound shown by the formula VI (X is halogen) to give a compound shown by the formula IV, which is reacted with isopropylamine.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13178379A JPS5655358A (en) | 1979-10-15 | 1979-10-15 | Preparation of isopropylaminopropanol |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13178379A JPS5655358A (en) | 1979-10-15 | 1979-10-15 | Preparation of isopropylaminopropanol |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5655358A true JPS5655358A (en) | 1981-05-15 |
JPS6128660B2 JPS6128660B2 (en) | 1986-07-01 |
Family
ID=15066037
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP13178379A Granted JPS5655358A (en) | 1979-10-15 | 1979-10-15 | Preparation of isopropylaminopropanol |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5655358A (en) |
-
1979
- 1979-10-15 JP JP13178379A patent/JPS5655358A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6128660B2 (en) | 1986-07-01 |
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