JPS5655358A - Preparation of isopropylaminopropanol - Google Patents

Preparation of isopropylaminopropanol

Info

Publication number
JPS5655358A
JPS5655358A JP13178379A JP13178379A JPS5655358A JP S5655358 A JPS5655358 A JP S5655358A JP 13178379 A JP13178379 A JP 13178379A JP 13178379 A JP13178379 A JP 13178379A JP S5655358 A JPS5655358 A JP S5655358A
Authority
JP
Japan
Prior art keywords
compound shown
formula
agent
reacted
reacting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP13178379A
Other languages
Japanese (ja)
Other versions
JPS6128660B2 (en
Inventor
Yoshitsugu Yamada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Toatsu Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals Inc filed Critical Mitsui Toatsu Chemicals Inc
Priority to JP13178379A priority Critical patent/JPS5655358A/en
Publication of JPS5655358A publication Critical patent/JPS5655358A/en
Publication of JPS6128660B2 publication Critical patent/JPS6128660B2/ja
Granted legal-status Critical Current

Links

Abstract

PURPOSE: To obtain the titled compound through a simple method useful as a β- adrenergic neuronal blocking agent, etc. etc., by reacting a specific isopropylaminopropanol derivative with an alcohol in the presence of a condensation agent.
CONSTITUTION: A compound shown by the formula I (R is H or alkyl) is reacted with a compound shown by the formula II (R1 is saturated or unsaturated aliphatic hydrocarbon), to give a compound shown by the formula III or its salt. The reaction is carried out in the presence of an alkali cendensation agent at room temperature to 100°C. The compound shown by the formula III, e.g., 1-isopropylamino-2-hydroxy-3- (2-allyloxyphenoxy)-propane is effective as a remedy for breast pang, arrhythmia, etc. The compound shown by the formula I, for example, is obtained readily by reacting a compound shown by the formula V with a compound shown by the formula VI (X is halogen) to give a compound shown by the formula IV, which is reacted with isopropylamine.
COPYRIGHT: (C)1981,JPO&Japio
JP13178379A 1979-10-15 1979-10-15 Preparation of isopropylaminopropanol Granted JPS5655358A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP13178379A JPS5655358A (en) 1979-10-15 1979-10-15 Preparation of isopropylaminopropanol

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13178379A JPS5655358A (en) 1979-10-15 1979-10-15 Preparation of isopropylaminopropanol

Publications (2)

Publication Number Publication Date
JPS5655358A true JPS5655358A (en) 1981-05-15
JPS6128660B2 JPS6128660B2 (en) 1986-07-01

Family

ID=15066037

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13178379A Granted JPS5655358A (en) 1979-10-15 1979-10-15 Preparation of isopropylaminopropanol

Country Status (1)

Country Link
JP (1) JPS5655358A (en)

Also Published As

Publication number Publication date
JPS6128660B2 (en) 1986-07-01

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