JPS565480A - 1 benzopyrano 2*33b xanthene derivative and its preparation - Google Patents
1 benzopyrano 2*33b xanthene derivative and its preparationInfo
- Publication number
- JPS565480A JPS565480A JP8087179A JP8087179A JPS565480A JP S565480 A JPS565480 A JP S565480A JP 8087179 A JP8087179 A JP 8087179A JP 8087179 A JP8087179 A JP 8087179A JP S565480 A JPS565480 A JP S565480A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- benzopyrano
- preparation
- xanthene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000001834 xanthenyl group Chemical class C1=CC=CC=2OC3=CC=CC=C3C(C12)* 0.000 title 1
- JLTDJTHDQAWBAV-UHFFFAOYSA-N N,N-dimethylaniline Chemical compound CN(C)C1=CC=CC=C1 JLTDJTHDQAWBAV-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- GUSWJGOYDXFJSI-UHFFFAOYSA-N 3,6-dichloropyridazine Chemical compound ClC1=CC=C(Cl)N=N1 GUSWJGOYDXFJSI-UHFFFAOYSA-N 0.000 abstract 1
- GJCOSYZMQJWQCA-UHFFFAOYSA-N 9H-xanthene Chemical compound C1=CC=C2CC3=CC=CC=C3OC2=C1 GJCOSYZMQJWQCA-UHFFFAOYSA-N 0.000 abstract 1
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 abstract 1
- 239000003905 agrochemical Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- QDLAGTHXVHQKRE-UHFFFAOYSA-N lichenxanthone Natural products COC1=CC(O)=C2C(=O)C3=C(C)C=C(OC)C=C3OC2=C1 QDLAGTHXVHQKRE-UHFFFAOYSA-N 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000002989 phenols Chemical class 0.000 abstract 1
- 150000004892 pyridazines Chemical class 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Landscapes
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A compound of formula I (R1, R2, R3, R4 and R5 are H or lower alkyl groups; X is lowr alkyl, halogen, lower alkyenyl, lower alkoxy group, etc.; n is 0, 1 or 2).
EXAMPLE: 5a,12a-Etheno-6H,6aH,7H,13H,13aH,14H-[ 1 ]benzopyrano[ 2,3-b ] xanthene.
USE: A medicine having an analgesic and an anti-inflammatory actions or an intermediate for the synthesis of other medicines or agricultural chemicals.
PROCESS: A 3,6-bis(2-alkenylphenoxy)pyridazine derivative of formula II is heated with preferably an inert solvent, e.g. N,N-dimethylaniline, or an inert solid carrier, e.g. anhydrous sodium carbonate, at 150°C or above to give the compound of formula I. The starting novel compound of formula II is obtained by heating one mole of 3,6-dichloropyridazine with 2 moles or more of the corresponding 2-alkenyl substituted phenol in the presence of a base.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8087179A JPS565480A (en) | 1979-06-27 | 1979-06-27 | 1 benzopyrano 2*33b xanthene derivative and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8087179A JPS565480A (en) | 1979-06-27 | 1979-06-27 | 1 benzopyrano 2*33b xanthene derivative and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS565480A true JPS565480A (en) | 1981-01-20 |
| JPS6356229B2 JPS6356229B2 (en) | 1988-11-07 |
Family
ID=13730397
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8087179A Granted JPS565480A (en) | 1979-06-27 | 1979-06-27 | 1 benzopyrano 2*33b xanthene derivative and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS565480A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61111398A (en) * | 1984-10-30 | 1986-05-29 | キャストロール・リミテッド | Mechanical processing of cobalt-containing metal |
| US7579350B2 (en) * | 2005-03-11 | 2009-08-25 | The Scripps Research Institute | Scaffolds for α-helix mimicry |
-
1979
- 1979-06-27 JP JP8087179A patent/JPS565480A/en active Granted
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61111398A (en) * | 1984-10-30 | 1986-05-29 | キャストロール・リミテッド | Mechanical processing of cobalt-containing metal |
| US7579350B2 (en) * | 2005-03-11 | 2009-08-25 | The Scripps Research Institute | Scaffolds for α-helix mimicry |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6356229B2 (en) | 1988-11-07 |
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