JPS5687565A - Production of alpha-arylpyridineacetic ester - Google Patents

Production of alpha-arylpyridineacetic ester

Info

Publication number
JPS5687565A
JPS5687565A JP16411379A JP16411379A JPS5687565A JP S5687565 A JPS5687565 A JP S5687565A JP 16411379 A JP16411379 A JP 16411379A JP 16411379 A JP16411379 A JP 16411379A JP S5687565 A JPS5687565 A JP S5687565A
Authority
JP
Japan
Prior art keywords
compound
formula
reaction
base catalyst
ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP16411379A
Other languages
Japanese (ja)
Inventor
Yoshiro Furuya
Noriaki Kihara
Tatsukazu Ishida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Petrochemical Industries Ltd
Original Assignee
Mitsui Petrochemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Petrochemical Industries Ltd filed Critical Mitsui Petrochemical Industries Ltd
Priority to JP16411379A priority Critical patent/JPS5687565A/en
Publication of JPS5687565A publication Critical patent/JPS5687565A/en
Pending legal-status Critical Current

Links

Abstract

PURPOSE: The reaction of benzylpyridine with a carbonate ester is conducted in the presence of a strong base catalyst in a specific temperature range to produce the titled substance used as a medicine or its intermediate through one step in high yield.
CONSTITUTION: The reaction between a compound a formula I [R1, R3 are H, hydrocarbon group, halogen; R2 is H, hydrocabon group, -R4N(R5)(R6) (R4 is alkylene; R5, R6 are alkyl or bind with each other to form alkylene)] and a compound of formula II (R7, R8 are hydrocarbon group) is carried out using a strong base catalyst such as sodium hydride at 70W150°C to give the compound of formula III or IV. In the reaction, the amount of the compound of formula II is 1W10 times the molar quantity of the compound of formula I usually and the excess amount of a carbonate ester is desirably used as a solvent. The base catalyst is usually used by 1W5mol based on the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP16411379A 1979-12-19 1979-12-19 Production of alpha-arylpyridineacetic ester Pending JPS5687565A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16411379A JPS5687565A (en) 1979-12-19 1979-12-19 Production of alpha-arylpyridineacetic ester

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16411379A JPS5687565A (en) 1979-12-19 1979-12-19 Production of alpha-arylpyridineacetic ester

Publications (1)

Publication Number Publication Date
JPS5687565A true JPS5687565A (en) 1981-07-16

Family

ID=15786992

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16411379A Pending JPS5687565A (en) 1979-12-19 1979-12-19 Production of alpha-arylpyridineacetic ester

Country Status (1)

Country Link
JP (1) JPS5687565A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997022588A1 (en) * 1995-12-18 1997-06-26 Bayer Aktiengesellschaft Use of hetarylacetic acid derivatives as leukotriene inhibitors

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997022588A1 (en) * 1995-12-18 1997-06-26 Bayer Aktiengesellschaft Use of hetarylacetic acid derivatives as leukotriene inhibitors

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