JPS5649389A - Novel cephem compound, its preparation, and preventive and remedy for microbism - Google Patents

Novel cephem compound, its preparation, and preventive and remedy for microbism

Info

Publication number
JPS5649389A
JPS5649389A JP13118580A JP13118580A JPS5649389A JP S5649389 A JPS5649389 A JP S5649389A JP 13118580 A JP13118580 A JP 13118580A JP 13118580 A JP13118580 A JP 13118580A JP S5649389 A JPS5649389 A JP S5649389A
Authority
JP
Japan
Prior art keywords
compound
formula
microbism
remedy
preventive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP13118580A
Other languages
Japanese (ja)
Inventor
Takao Takatani
Masayoshi Murata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/079,796 external-priority patent/US4288436A/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of JPS5649389A publication Critical patent/JPS5649389A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:A cephem compound of formula I [R1 is (protected) NH2; R2 is methyl, isopropyl, allyl, etc.; R3 is (protected) COOH; R4 is methoxycarbonylmethyl, carboxyethyl, etc.] and its salt.
EXAMPLE: 7-[ 2-Benzyloxyimino-2-( 2-aminothiazol-4-yl )acetamido]-3-( 1-carboxymethyl-1H-tetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid (syn-isomer).
USE: Antibacterial agent effective to a number of pathogenic bacteria including Gram- positive and Gram-negative bacteria.
PROCESS: The compound of formula I is prepared by reacting e.g. a compound of formula II or its reactive derivative or their salts with a compound of formula III or its reactive derivative or their salts, in a solvent, if necessary in the presence of a condensing agent or a base.
COPYRIGHT: (C)1981,JPO&Japio
JP13118580A 1979-09-28 1980-09-19 Novel cephem compound, its preparation, and preventive and remedy for microbism Pending JPS5649389A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/079,796 US4288436A (en) 1977-04-13 1979-09-28 3,7-Disubstituted-3-cephem-4-carboxylic acid compounds

Publications (1)

Publication Number Publication Date
JPS5649389A true JPS5649389A (en) 1981-05-02

Family

ID=22152873

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13118580A Pending JPS5649389A (en) 1979-09-28 1980-09-19 Novel cephem compound, its preparation, and preventive and remedy for microbism

Country Status (1)

Country Link
JP (1) JPS5649389A (en)

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