JPS5646813A - Antitumorigenic composition - Google Patents
Antitumorigenic compositionInfo
- Publication number
- JPS5646813A JPS5646813A JP12487979A JP12487979A JPS5646813A JP S5646813 A JPS5646813 A JP S5646813A JP 12487979 A JP12487979 A JP 12487979A JP 12487979 A JP12487979 A JP 12487979A JP S5646813 A JPS5646813 A JP S5646813A
- Authority
- JP
- Japan
- Prior art keywords
- uracil
- antitumorigenic
- fluorouracil
- formula
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
PURPOSE: An antitumorigenic preparation that contains a 5-fluorouracil and a specific amount of a uracil.
CONSTITUTION: One mole of at least one 5-fluorouracil selected from the compounds of the formula (R1, R2 are H, alkoxymethyl, tetrahydrofuryl, alkylcarbamoyl) and over 20moles of at least one uracil selected from the group consisting of thymine, thymidine, uridine, 2'-deoxyuridine, cytosine, cytidine and 2'-dioxycytidine are included to give a preparation in a form of tablet, capsule or granule for oral administration, or injectable or suppository for parenteral application. The amount of the compound of the formula is suitably 0.5W50mg/kg a day. The combination of a uracil that has no carcinostatic activity develops synergism in carcinostatic effect and increases remarkably the therapeutic index.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12487979A JPS5646813A (en) | 1979-09-27 | 1979-09-27 | Antitumorigenic composition |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12487979A JPS5646813A (en) | 1979-09-27 | 1979-09-27 | Antitumorigenic composition |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5646813A true JPS5646813A (en) | 1981-04-28 |
Family
ID=14896345
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP12487979A Pending JPS5646813A (en) | 1979-09-27 | 1979-09-27 | Antitumorigenic composition |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5646813A (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5335834A (en) * | 1976-09-13 | 1978-04-03 | Yoshinobu Watanabe | Hydraulic pressure machine for power generation |
JPS5392813A (en) * | 1976-12-23 | 1978-08-15 | Commercial Decal Inc | Heattparting decarcomania and parting paper |
JPS53137686A (en) * | 1977-05-06 | 1978-12-01 | Matsushita Electric Ind Co Ltd | Semiconductor laser unit |
-
1979
- 1979-09-27 JP JP12487979A patent/JPS5646813A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5335834A (en) * | 1976-09-13 | 1978-04-03 | Yoshinobu Watanabe | Hydraulic pressure machine for power generation |
JPS5392813A (en) * | 1976-12-23 | 1978-08-15 | Commercial Decal Inc | Heattparting decarcomania and parting paper |
JPS53137686A (en) * | 1977-05-06 | 1978-12-01 | Matsushita Electric Ind Co Ltd | Semiconductor laser unit |
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