JPS5519245A - Anti-malignant tumor agent composition - Google Patents
Anti-malignant tumor agent compositionInfo
- Publication number
- JPS5519245A JPS5519245A JP9281378A JP9281378A JPS5519245A JP S5519245 A JPS5519245 A JP S5519245A JP 9281378 A JP9281378 A JP 9281378A JP 9281378 A JP9281378 A JP 9281378A JP S5519245 A JPS5519245 A JP S5519245A
- Authority
- JP
- Japan
- Prior art keywords
- fluorouracil
- agent composition
- malignant tumor
- tumor agent
- fluorouracils
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: The title composition having prolonged duration with suppressed decomposition and inactivation in the living body, comprising 5-fluorouracils and uracils.
CONSTITUTION: A composition comprising (A) one mole of 5-fluorouracils of the formula (R1 and R2 are H, alkoxymethyl, tetrahydrofuryl, or alkylcarbamoyl groups), e.g. 5-fluorouracil, 1-(2-tetrahydrofuryl)-5-fluorouracil, and (B) 0.5W 20 moles of at least one type of uracil selected from 1-n-hexylcarbamoyluracil, cytosine, sytidine, and 2'-deoxycytidine. The decomposition and inactivation of the 5-fluorouracil formed in the living body can be suppressed to improve the antitumor effect.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9281378A JPS5519245A (en) | 1978-07-28 | 1978-07-28 | Anti-malignant tumor agent composition |
GB7908960A GB2016921B (en) | 1978-03-27 | 1979-03-14 | Anti cancer compositions containing uracil derivatives |
CH272679A CH639274A5 (en) | 1978-03-27 | 1979-03-23 | ANTI-DRINKING AGENTS. |
FR7907523A FR2420974A1 (en) | 1978-03-27 | 1979-03-26 | MEDICINE BASED ON URACIL DERIVATIVES |
IT67629/79A IT1119283B (en) | 1978-03-27 | 1979-03-27 | ANTI-CANCER COMPOSITION |
DE2912112A DE2912112C2 (en) | 1978-03-27 | 1979-03-27 | Anti-cancer drug |
US06/552,263 US4650801A (en) | 1978-03-27 | 1983-11-16 | Anti-cancer compositions for delivering 5-fluorouracil |
US06/932,516 US4914105A (en) | 1978-03-27 | 1986-11-20 | Anti-cancer compositions for delivering 5-fluorouracil |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9281378A JPS5519245A (en) | 1978-07-28 | 1978-07-28 | Anti-malignant tumor agent composition |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5519245A true JPS5519245A (en) | 1980-02-09 |
JPS6223724B2 JPS6223724B2 (en) | 1987-05-25 |
Family
ID=14064847
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9281378A Granted JPS5519245A (en) | 1978-03-27 | 1978-07-28 | Anti-malignant tumor agent composition |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5519245A (en) |
-
1978
- 1978-07-28 JP JP9281378A patent/JPS5519245A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6223724B2 (en) | 1987-05-25 |
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