JPS5519245A - Anti-malignant tumor agent composition - Google Patents

Anti-malignant tumor agent composition

Info

Publication number
JPS5519245A
JPS5519245A JP9281378A JP9281378A JPS5519245A JP S5519245 A JPS5519245 A JP S5519245A JP 9281378 A JP9281378 A JP 9281378A JP 9281378 A JP9281378 A JP 9281378A JP S5519245 A JPS5519245 A JP S5519245A
Authority
JP
Japan
Prior art keywords
fluorouracil
agent composition
malignant tumor
tumor agent
fluorouracils
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP9281378A
Other languages
Japanese (ja)
Other versions
JPS6223724B2 (en
Inventor
Setsuo Fujii
Norio Saimi
Setsuo Takeda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taiho Pharmaceutical Co Ltd
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Priority to JP9281378A priority Critical patent/JPS5519245A/en
Priority to GB7908960A priority patent/GB2016921B/en
Priority to CH272679A priority patent/CH639274A5/en
Priority to FR7907523A priority patent/FR2420974A1/en
Priority to IT67629/79A priority patent/IT1119283B/en
Priority to DE2912112A priority patent/DE2912112C2/en
Publication of JPS5519245A publication Critical patent/JPS5519245A/en
Priority to US06/552,263 priority patent/US4650801A/en
Priority to US06/932,516 priority patent/US4914105A/en
Publication of JPS6223724B2 publication Critical patent/JPS6223724B2/ja
Granted legal-status Critical Current

Links

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: The title composition having prolonged duration with suppressed decomposition and inactivation in the living body, comprising 5-fluorouracils and uracils.
CONSTITUTION: A composition comprising (A) one mole of 5-fluorouracils of the formula (R1 and R2 are H, alkoxymethyl, tetrahydrofuryl, or alkylcarbamoyl groups), e.g. 5-fluorouracil, 1-(2-tetrahydrofuryl)-5-fluorouracil, and (B) 0.5W 20 moles of at least one type of uracil selected from 1-n-hexylcarbamoyluracil, cytosine, sytidine, and 2'-deoxycytidine. The decomposition and inactivation of the 5-fluorouracil formed in the living body can be suppressed to improve the antitumor effect.
COPYRIGHT: (C)1980,JPO&Japio
JP9281378A 1978-03-27 1978-07-28 Anti-malignant tumor agent composition Granted JPS5519245A (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP9281378A JPS5519245A (en) 1978-07-28 1978-07-28 Anti-malignant tumor agent composition
GB7908960A GB2016921B (en) 1978-03-27 1979-03-14 Anti cancer compositions containing uracil derivatives
CH272679A CH639274A5 (en) 1978-03-27 1979-03-23 ANTI-DRINKING AGENTS.
FR7907523A FR2420974A1 (en) 1978-03-27 1979-03-26 MEDICINE BASED ON URACIL DERIVATIVES
IT67629/79A IT1119283B (en) 1978-03-27 1979-03-27 ANTI-CANCER COMPOSITION
DE2912112A DE2912112C2 (en) 1978-03-27 1979-03-27 Anti-cancer drug
US06/552,263 US4650801A (en) 1978-03-27 1983-11-16 Anti-cancer compositions for delivering 5-fluorouracil
US06/932,516 US4914105A (en) 1978-03-27 1986-11-20 Anti-cancer compositions for delivering 5-fluorouracil

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9281378A JPS5519245A (en) 1978-07-28 1978-07-28 Anti-malignant tumor agent composition

Publications (2)

Publication Number Publication Date
JPS5519245A true JPS5519245A (en) 1980-02-09
JPS6223724B2 JPS6223724B2 (en) 1987-05-25

Family

ID=14064847

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9281378A Granted JPS5519245A (en) 1978-03-27 1978-07-28 Anti-malignant tumor agent composition

Country Status (1)

Country Link
JP (1) JPS5519245A (en)

Also Published As

Publication number Publication date
JPS6223724B2 (en) 1987-05-25

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