JPS5626198A - Preparation of antitumor substance - Google Patents

Preparation of antitumor substance

Info

Publication number
JPS5626198A
JPS5626198A JP10110079A JP10110079A JPS5626198A JP S5626198 A JPS5626198 A JP S5626198A JP 10110079 A JP10110079 A JP 10110079A JP 10110079 A JP10110079 A JP 10110079A JP S5626198 A JPS5626198 A JP S5626198A
Authority
JP
Japan
Prior art keywords
mycelium
incubated
antitumor
stroma
extracted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10110079A
Other languages
English (en)
Other versions
JPS5646793B2 (ja
Inventor
Kazuo Nakajima
Yoshiaki Hirata
Hiroyuki Uchida
Yoshie Watabe
Tsutomu Taniguchi
Akira Obayashi
Sai Tanabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takara Shuzo Co Ltd
Original Assignee
Takara Shuzo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takara Shuzo Co Ltd filed Critical Takara Shuzo Co Ltd
Priority to JP10110079A priority Critical patent/JPS5626198A/ja
Priority to CA000357553A priority patent/CA1139748A/en
Priority to GB8025345A priority patent/GB2055873B/en
Priority to CH6003/80A priority patent/CH648595A5/de
Priority to FR8017465A priority patent/FR2463185A1/fr
Priority to DE19803030107 priority patent/DE3030107A1/de
Priority to US06/231,575 priority patent/US4409385A/en
Publication of JPS5626198A publication Critical patent/JPS5626198A/ja
Publication of JPS5646793B2 publication Critical patent/JPS5646793B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/005Glycopeptides, glycoproteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/145Fungal isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/02Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/645Fungi ; Processes using fungi

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP10110079A 1979-08-08 1979-08-08 Preparation of antitumor substance Granted JPS5626198A (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP10110079A JPS5626198A (en) 1979-08-08 1979-08-08 Preparation of antitumor substance
CA000357553A CA1139748A (en) 1979-08-08 1980-08-01 Polysaccharides having anticarcinogenic activity and method for producing same
GB8025345A GB2055873B (en) 1979-08-08 1980-08-04 Polysaccharides having anticarcinogenic activity and method for producing same
CH6003/80A CH648595A5 (de) 1979-08-08 1980-08-07 Verfahren zur herstellung von polysacchariden mit antikarzinogener aktivitaet.
FR8017465A FR2463185A1 (fr) 1979-08-08 1980-08-07 Polysaccharides doues d'activite anti-cancereuse provenant de la culture d'une souche du genre isaria et leur procede de production
DE19803030107 DE3030107A1 (de) 1979-08-08 1980-08-08 Polysaccharid mit antikarzinogener aktivitaet und verfahren zu seiner herstellung
US06/231,575 US4409385A (en) 1979-08-08 1981-02-03 Polysaccharides having anticarcinogenic activity and method for producing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10110079A JPS5626198A (en) 1979-08-08 1979-08-08 Preparation of antitumor substance

Publications (2)

Publication Number Publication Date
JPS5626198A true JPS5626198A (en) 1981-03-13
JPS5646793B2 JPS5646793B2 (ja) 1981-11-05

Family

ID=14291663

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10110079A Granted JPS5626198A (en) 1979-08-08 1979-08-08 Preparation of antitumor substance

Country Status (7)

Country Link
US (1) US4409385A (ja)
JP (1) JPS5626198A (ja)
CA (1) CA1139748A (ja)
CH (1) CH648595A5 (ja)
DE (1) DE3030107A1 (ja)
FR (1) FR2463185A1 (ja)
GB (1) GB2055873B (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4528188A (en) * 1981-04-30 1985-07-09 Zenyaku Kogyo Kabushiki Kaisha Polysaccharide PS-A obtained from barrenwort deriving from plants belonging to the genus Epimedium, process for preparation thereof and phylactic and immunostimulating agents comprising said polysaccharide PS-A effective component
CN1087748C (zh) * 1999-07-22 2002-07-17 中国医学科学院医药生物技术研究所 具有il-1受体拮抗活性的微生物多糖或其盐或水解产物,其制备方法和含有它的药物组合物
JPWO2004074269A1 (ja) * 2003-02-20 2006-06-01 明治製菓株式会社 Tk−57−164a物質及びtk−57−164b物質、並びにそれらの製造法及びそれらを有効成分とする農園芸用殺菌剤

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3314801A (en) * 1963-10-24 1967-04-18 Martin C Cadmus Microbial polysaccharide and process
US3436346A (en) * 1968-06-10 1969-04-01 Pillsbury Co Process for preparing filterable aqueous polysaccharide solutions
US3923782A (en) * 1973-05-29 1975-12-02 Cornell Res Foundation Inc Production of heteropolysaccharide by fermentation of methanol
JPS5290614A (en) * 1975-12-18 1977-07-30 Kureha Chem Ind Co Ltd Preparation of anti-tumor substance
JPS536412A (en) * 1976-07-07 1978-01-20 Kureha Chem Ind Co Ltd Preparation of n-containing polysaccharides
FR2407262A1 (fr) * 1977-10-27 1979-05-25 Cassenne Lab Sa Nouveaux polysaccharides extraits de corps microbiens d'haemophilus influenzae, procede de preparation et application a titre de medicaments de ces nouveaux produits
US4268505A (en) * 1978-04-13 1981-05-19 Kureha Kagaku Kogyo Kabushiki Kaisha Pharmaceutical composition comprising a nitrogen-containing polysaccharide and an antibiotic agent, and a method of treating an infectious disease therewith

Also Published As

Publication number Publication date
CA1139748A (en) 1983-01-18
FR2463185A1 (fr) 1981-02-20
CH648595A5 (de) 1985-03-29
GB2055873A (en) 1981-03-11
DE3030107A1 (de) 1981-02-26
GB2055873B (en) 1983-05-05
US4409385A (en) 1983-10-11
DE3030107C2 (ja) 1988-02-18
FR2463185B1 (ja) 1983-08-12
JPS5646793B2 (ja) 1981-11-05

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