JPS5625149A - Keto ester derivative and its preparation - Google Patents
Keto ester derivative and its preparationInfo
- Publication number
- JPS5625149A JPS5625149A JP10031079A JP10031079A JPS5625149A JP S5625149 A JPS5625149 A JP S5625149A JP 10031079 A JP10031079 A JP 10031079A JP 10031079 A JP10031079 A JP 10031079A JP S5625149 A JPS5625149 A JP S5625149A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- keto ester
- preparation
- fluorine
- reacted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229930194542 Keto Natural products 0.000 title abstract 2
- -1 Keto ester Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 4
- 229910052731 fluorine Inorganic materials 0.000 abstract 2
- 239000011737 fluorine Substances 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- XKSAJZSJKURQRX-UHFFFAOYSA-N 2-acetyloxy-5-(4-fluorophenyl)benzoic acid Chemical compound C1=C(C(O)=O)C(OC(=O)C)=CC=C1C1=CC=C(F)C=C1 XKSAJZSJKURQRX-UHFFFAOYSA-N 0.000 abstract 1
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000005110 aryl thio group Chemical group 0.000 abstract 1
- AWHNUHMUCGRKRA-UHFFFAOYSA-N benzylsulfonylmethylbenzene Chemical class C=1C=CC=CC=1CS(=O)(=O)CC1=CC=CC=C1 AWHNUHMUCGRKRA-UHFFFAOYSA-N 0.000 abstract 1
- 239000003139 biocide Substances 0.000 abstract 1
- HUPFGZXOMWLGNK-UHFFFAOYSA-N diflunisal Chemical compound C1=C(O)C(C(=O)O)=CC(C=2C(=CC(F)=CC=2)F)=C1 HUPFGZXOMWLGNK-UHFFFAOYSA-N 0.000 abstract 1
- 229960000616 diflunisal Drugs 0.000 abstract 1
- 229950007979 flufenisal Drugs 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- LQXGMYGBXXWQFG-UHFFFAOYSA-N methyl 5-(benzenesulfonyl)-5-(4-chlorophenyl)-2-oxocyclohexane-1-carboxylate Chemical compound C1CC(=O)C(C(=O)OC)CC1(S(=O)(=O)C=1C=CC=CC=1)C1=CC=C(Cl)C=C1 LQXGMYGBXXWQFG-UHFFFAOYSA-N 0.000 abstract 1
- 230000003119 painkilling effect Effects 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10031079A JPS5625149A (en) | 1979-08-08 | 1979-08-08 | Keto ester derivative and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10031079A JPS5625149A (en) | 1979-08-08 | 1979-08-08 | Keto ester derivative and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5625149A true JPS5625149A (en) | 1981-03-10 |
| JPS621392B2 JPS621392B2 (enrdf_load_stackoverflow) | 1987-01-13 |
Family
ID=14270592
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10031079A Granted JPS5625149A (en) | 1979-08-08 | 1979-08-08 | Keto ester derivative and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5625149A (enrdf_load_stackoverflow) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4667055A (en) * | 1983-12-29 | 1987-05-19 | Merck Frosst Canada, Inc. | Leukotriene antagonists |
| US4871756A (en) * | 1985-03-20 | 1989-10-03 | Merck Frosst Canada, Inc. | Leukotriene antagonists |
| JP2004533428A (ja) * | 2001-04-05 | 2004-11-04 | メルク シャープ エンド ドーム リミテッド | γ−セクレターゼの作用を調節するスルホン |
| US7101895B2 (en) | 2002-10-04 | 2006-09-05 | Merck Sharp & Dohme Limited | Cyclohexyl sulphone derivatives as gamma-secretase inhibitors |
| US7304094B2 (en) | 2001-08-21 | 2007-12-04 | Merck Sharp + Dohme | Cyclohexyl sulphones |
-
1979
- 1979-08-08 JP JP10031079A patent/JPS5625149A/ja active Granted
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4667055A (en) * | 1983-12-29 | 1987-05-19 | Merck Frosst Canada, Inc. | Leukotriene antagonists |
| US4871756A (en) * | 1985-03-20 | 1989-10-03 | Merck Frosst Canada, Inc. | Leukotriene antagonists |
| JP2004533428A (ja) * | 2001-04-05 | 2004-11-04 | メルク シャープ エンド ドーム リミテッド | γ−セクレターゼの作用を調節するスルホン |
| US7595344B2 (en) | 2001-04-05 | 2009-09-29 | Merck Sharp & Dohme Limited | Sulphones which modulate the action of gamma secretase |
| US7598386B2 (en) | 2001-04-05 | 2009-10-06 | Merck Sharp & Dohme Limited | Sulphones which modulate the action of gamma-secretase |
| US7304094B2 (en) | 2001-08-21 | 2007-12-04 | Merck Sharp + Dohme | Cyclohexyl sulphones |
| US7101895B2 (en) | 2002-10-04 | 2006-09-05 | Merck Sharp & Dohme Limited | Cyclohexyl sulphone derivatives as gamma-secretase inhibitors |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS621392B2 (enrdf_load_stackoverflow) | 1987-01-13 |
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