JPS5622326A - Novel insulin derivative and its manufacture - Google Patents

Novel insulin derivative and its manufacture

Info

Publication number
JPS5622326A
JPS5622326A JP10137080A JP10137080A JPS5622326A JP S5622326 A JPS5622326 A JP S5622326A JP 10137080 A JP10137080 A JP 10137080A JP 10137080 A JP10137080 A JP 10137080A JP S5622326 A JPS5622326 A JP S5622326A
Authority
JP
Japan
Prior art keywords
insulin
insulin derivative
manufacture
derivative
monoalkylpolyethyleneglycol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10137080A
Other languages
English (en)
Inventor
Ooberumaieru Rainaa
Uuman Rainaa
Zumu Hansuudeiiteru
Regitsutsu Giyuntaa
Gaizen Karuru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of JPS5622326A publication Critical patent/JPS5622326A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
JP10137080A 1979-07-27 1980-07-25 Novel insulin derivative and its manufacture Pending JPS5622326A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792930542 DE2930542A1 (de) 1979-07-27 1979-07-27 Neue insulinderivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
JPS5622326A true JPS5622326A (en) 1981-03-02

Family

ID=6076963

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10137080A Pending JPS5622326A (en) 1979-07-27 1980-07-25 Novel insulin derivative and its manufacture

Country Status (7)

Country Link
EP (1) EP0027161B1 (ja)
JP (1) JPS5622326A (ja)
AT (1) ATE3145T1 (ja)
CA (1) CA1156217A (ja)
DE (2) DE2930542A1 (ja)
DK (1) DK324380A (ja)
ES (1) ES8104202A1 (ja)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61178926A (ja) * 1984-03-06 1986-08-11 Takeda Chem Ind Ltd 化学修飾ペプチドホルモンおよびその製造法
JP2003206236A (ja) * 1993-05-10 2003-07-22 Nobex Corp 接合安定化されたポリペプチド組成物
JP2007162329A (ja) * 2005-12-14 2007-06-28 Fujita Corp 既存鋼製構造物の補強方法
JP2008038335A (ja) * 2006-08-01 2008-02-21 Fujita Corp 既存鋼構造部材の補強工法
JP2008121240A (ja) * 2006-11-10 2008-05-29 Fujita Corp 既存鋼構造部材の補強構造
CN107446038A (zh) * 2016-06-01 2017-12-08 湖南华腾制药有限公司 聚乙二醇修饰的重组人胰岛素及其制备方法

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3819079A1 (de) * 1988-06-04 1989-12-07 Hoechst Ag Hirudin-derivate mit verzoegerter wirkung
US5286637A (en) * 1989-08-07 1994-02-15 Debiopharm, S.A. Biologically active drug polymer derivatives and method for preparing same
US5824784A (en) 1994-10-12 1998-10-20 Amgen Inc. N-terminally chemically modified protein compositions and methods
US6323311B1 (en) * 1999-09-22 2001-11-27 University Of Utah Research Foundation Synthesis of insulin derivatives
WO2004091494A2 (en) * 2003-04-11 2004-10-28 Pr Pharmaceuticals Inc. Method for preparation of site-specific protein conjugates
EP2043693B1 (en) 2006-07-25 2016-04-27 Lipoxen Technologies Limited N-terminal derivatisation of insulin with polysialic acid
US10188739B2 (en) 2014-02-27 2019-01-29 Xenetic Biosciences, Inc. Compositions and methods for administering insulin or insulin-like protein to the brain

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2038121A1 (de) * 1970-07-31 1972-02-03 Hoechst Ag Acylderivate des Insulins und Verfahren zu ihrer Herstellung
DE2047413C3 (de) * 1970-09-26 1980-05-29 F. Hoffmann-La Roche & Co Ag, Basel (Schweiz) Verfahren zur Herstellung von Peptiden in homogener Phase
DE2433883C2 (de) * 1973-07-20 1986-03-27 Research Corp., New York, N.Y. Verwendung von physiologisch aktiven Polypeptiden
DE2360794C2 (de) * 1973-12-06 1984-12-06 Hoechst Ag, 6230 Frankfurt Verfahren zur Herstellung von Peptiden

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61178926A (ja) * 1984-03-06 1986-08-11 Takeda Chem Ind Ltd 化学修飾ペプチドホルモンおよびその製造法
JP2003206236A (ja) * 1993-05-10 2003-07-22 Nobex Corp 接合安定化されたポリペプチド組成物
JP2007162329A (ja) * 2005-12-14 2007-06-28 Fujita Corp 既存鋼製構造物の補強方法
JP2008038335A (ja) * 2006-08-01 2008-02-21 Fujita Corp 既存鋼構造部材の補強工法
JP2008121240A (ja) * 2006-11-10 2008-05-29 Fujita Corp 既存鋼構造部材の補強構造
CN107446038A (zh) * 2016-06-01 2017-12-08 湖南华腾制药有限公司 聚乙二醇修饰的重组人胰岛素及其制备方法

Also Published As

Publication number Publication date
ES493550A0 (es) 1981-04-16
EP0027161B1 (de) 1983-04-27
EP0027161A1 (de) 1981-04-22
CA1156217A (en) 1983-11-01
DE2930542A1 (de) 1981-02-12
ES8104202A1 (es) 1981-04-16
DK324380A (da) 1981-01-28
ATE3145T1 (de) 1983-05-15
DE3062890D1 (en) 1983-06-01

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