JPS5621040B2 - - Google Patents

Info

Publication number
JPS5621040B2
JPS5621040B2 JP4077873A JP4077873A JPS5621040B2 JP S5621040 B2 JPS5621040 B2 JP S5621040B2 JP 4077873 A JP4077873 A JP 4077873A JP 4077873 A JP4077873 A JP 4077873A JP S5621040 B2 JPS5621040 B2 JP S5621040B2
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP4077873A
Other languages
Japanese (ja)
Other versions
JPS497224A (Direct
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS497224A publication Critical patent/JPS497224A/ja
Publication of JPS5621040B2 publication Critical patent/JPS5621040B2/ja
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086Platinum compounds
    • C07F15/0093Platinum compounds without a metal-carbon linkage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP4077873A 1972-04-10 1973-04-10 Expired JPS5621040B2 (Direct)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB1634972A GB1432562A (en) 1972-04-10 1972-04-10 Platinum co-ordination compounds
GB1965672 1972-04-27
GB2138872 1972-05-08
GB2992072 1972-06-26
GB4179872 1972-09-08

Publications (2)

Publication Number Publication Date
JPS497224A JPS497224A (Direct) 1974-01-22
JPS5621040B2 true JPS5621040B2 (Direct) 1981-05-16

Family

ID=27516172

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4077873A Expired JPS5621040B2 (Direct) 1972-04-10 1973-04-10

Country Status (7)

Country Link
US (1) US3892790A (Direct)
JP (1) JPS5621040B2 (Direct)
DE (1) DE2318019C2 (Direct)
FR (1) FR2182941B1 (Direct)
GB (1) GB1432562A (Direct)
NL (1) NL182200C (Direct)
SE (1) SE400294B (Direct)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1578323A (en) * 1976-02-26 1980-11-05 Rustenburg Platinum Mines Ltd Compositions containing platinum
GB1585103A (en) * 1976-04-06 1981-02-25 Rustenburg Platinum Mines Ltd Pharmaceutical compositions containing platinum compounds
US4255417A (en) * 1976-08-04 1981-03-10 Johnson Matthey, Inc. Platinum compounds for the irradication of skin blemishes
US4115418A (en) * 1976-09-02 1978-09-19 Government Of The United States Of America 1,2-diaminocyclohexane platinum (ii) complexes having antineoplastic activity
JPS6041077B2 (ja) * 1976-09-06 1985-09-13 喜徳 喜谷 1,2‐ジアミノシクロヘキサン異性体のシス白金(2)錯体
US4175133A (en) * 1977-02-18 1979-11-20 United States Of America 1,2-Diaminocyclohexane platinum (II) complexes having antineoplastic activity against L1210 leukemia
US4278660A (en) * 1977-05-02 1981-07-14 Research Corporation Complex or salt of a platinum (II) compound and a nitrogen containing polymer
US4151185A (en) * 1977-05-02 1979-04-24 Research Corporation Complex or salt of a platinum (II) compound and a nitrogen containing polymer
US4137248A (en) * 1977-08-29 1979-01-30 The United States Of America As Represented By The Department Of Health, Education And Welfare Compound, 4-carboxyphthalato(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof
SE447385B (sv) * 1977-10-19 1986-11-10 Johnson Matthey Co Ltd Cis-koordinationsforeningar av platina
US4225529A (en) * 1977-10-19 1980-09-30 Johnson, Matthey & Co., Limited Compositions containing platinum
US4203912A (en) * 1977-10-19 1980-05-20 Johnson, Matthey & Co., Limited Compositions containing platinum
NL7807334A (nl) * 1978-07-06 1980-01-08 Tno Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een genees- middel met toepassing van een dergelijk platina-dia- minecomplex voor de behandeling van kanker, alsmede al- dus verkregen gevormd geneesmiddel.
JPS5554852A (en) * 1978-10-16 1980-04-22 Tsuneji Yamamoto Raw sea urchin eggs and method of treating them
JPS55130992A (en) * 1979-03-31 1980-10-11 Yoshinori Kitani Novel platinum complex
NL8101026A (nl) * 1981-03-03 1982-10-01 Tno Platinadiamine-complexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiamine-complex voor de behandeling van kanker alsmede aldus verkregen gevormd geneesmiddel.
JPS5896024A (ja) * 1981-10-16 1983-06-07 リチヤ−ド・エフ・ストツケル 白金毒解毒剤
US4578491A (en) * 1982-06-28 1986-03-25 Engelhard Corporation Bis(thiocyanato)palladium(II) complexes
IT1153974B (it) * 1982-09-23 1987-01-21 Erba Farmitalia Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento
US4560782A (en) * 1982-11-19 1985-12-24 Research Corporation Anti-tumor diplatinum coordination compounds
US4533502A (en) * 1983-02-22 1985-08-06 Rochon Fernande D Platinum (II) compounds and their preparation
US4617189A (en) * 1983-04-14 1986-10-14 Stockel Richard F Use of selenium-containing compounds for negating the toxic effects of platinum compounds used in chemotherapy, and a novel selenium-containing platinum compound and use thereof as an anti-cancer medicine
EP0210291A1 (en) * 1985-07-27 1987-02-04 American Cyanamid Company Platinum complexes of antitumor agents
US4544759A (en) * 1983-07-29 1985-10-01 American Cyanamid Company Platinum complexes of antitumor agents
GB8328218D0 (en) * 1983-10-21 1983-11-23 Johnson Matthey Plc Oral compositions
HU193809B (en) * 1984-09-12 1987-12-28 Chugai Pharmaceutical Co Ltd Process for producing new platinum complexes
US4588831A (en) * 1984-11-09 1986-05-13 Natec Platinum complex compounds of substituted 5,8-dihydroxyl-1,4-naphthoquinone, and process for their production and use
ATE86967T1 (de) * 1988-01-09 1993-04-15 Asta Medica Ag 1,2-bis(aminomethyl)cyclobutan-platin-komplexe.
GB9502799D0 (en) 1995-02-14 1995-04-05 Johnson Matthey Plc Improvements in platinum complexes
WO2001036431A1 (en) 1999-11-15 2001-05-25 Parker Hughes Institute Diamino platinum (ii) antitumor complexes
GB0011903D0 (en) * 2000-05-18 2000-07-05 Astrazeneca Ab Combination chemotherapy
US8173686B2 (en) 2006-11-06 2012-05-08 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8168662B1 (en) 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8168661B2 (en) * 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8178564B2 (en) * 2006-11-06 2012-05-15 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US20110033528A1 (en) * 2009-08-05 2011-02-10 Poniard Pharmaceuticals, Inc. Stabilized picoplatin oral dosage form
TW200916094A (en) * 2007-06-27 2009-04-16 Poniard Pharmaceuticals Inc Stabilized picoplatin dosage form
US20100260832A1 (en) * 2007-06-27 2010-10-14 Poniard Pharmaceuticals, Inc. Combination therapy for ovarian cancer
JP2010533714A (ja) * 2007-07-16 2010-10-28 ポニアード ファーマシューティカルズ, インコーポレイテッド ピコプラチンのための経口製剤
CA2715329A1 (en) * 2008-02-08 2009-08-13 Poniard Pharmaceuticals, Inc. Picoplatin and amrubicin to treat lung cancer
ES2609931T3 (es) 2010-06-18 2017-04-25 Myriad Genetics, Inc. Métodos y materiales para evaluar la pérdida de heterocigosidad
EP3109325B1 (en) 2010-08-24 2018-12-26 Dana-Farber Cancer Institute, Inc. Methods for predicting anti-cancer response
CA2839210A1 (en) 2011-06-17 2012-12-20 Myriad Genetics, Inc. Methods and materials for assessing allelic imbalance
ES2759533T5 (es) 2011-12-21 2023-06-22 Myriad Genetics Inc Métodos y materiales para evaluar la pérdida de heterocigosidad
ES2997859T3 (en) 2012-02-23 2025-02-18 Childrens Medical Center Methods for predicting response to parp inhibitors
US11091808B2 (en) 2012-06-07 2021-08-17 Institut Curie Methods for detecting inactivation of the homologous recombination pathway (BRCA1/2) in human tumors
WO2014160080A1 (en) 2013-03-14 2014-10-02 Children's Medical Center Corporation Cancer diagnosis, treatment selection and treatment
DK2981624T3 (da) 2013-04-05 2020-03-02 Myriad Genetics Inc Fremgangsmåder til vurdering af homolog rekombinationsdeficiens og forudsigelse af respons på cancerbehandling
EP3080292B1 (en) 2013-12-09 2022-02-02 Institut Curie Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors
ES2946251T3 (es) 2014-08-15 2023-07-14 Myriad Genetics Inc Métodos y materiales para evaluar la deficiencia de recombinación homóloga
EP4141127B1 (en) 2021-08-30 2024-10-09 Zentrum Familiärer Brust- und Eierstockkrebs Universitätsklinik Köln Method for assessing homologous recombination deficiency in ovarian cancer cells

Also Published As

Publication number Publication date
SE400294B (sv) 1978-03-20
GB1432562A (en) 1976-04-22
JPS497224A (Direct) 1974-01-22
DE2318019C2 (de) 1982-09-23
FR2182941A1 (Direct) 1973-12-14
NL7304880A (Direct) 1973-10-12
NL182200C (nl) 1988-02-01
US3892790A (en) 1975-07-01
FR2182941B1 (Direct) 1976-12-31
DE2318019A1 (de) 1973-11-08

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