JPS56164175A

JPS56164175A - Novel thiazole derivative and antipeptic ulcer agent containing the same as active constituent

Novel thiazole derivative and antipeptic ulcer agent containing the same as active constituent

Info

Publication number: JPS56164175A
Authority: JP; Japan
Prior art keywords: formula; compound; agent; thiazole derivative; same
Prior art date: 1980-05-23
Legal status : Granted

Application number

JP6850780A

Other languages

English (en)

Japanese (ja)

Other versions

JPS6310950B2 (enrdf_load_stackoverflow

Inventor

Takao Kawasaki

Yoshiaki Osaka

Tadashi Tsuchiya

Current Assignee

Kureha Corp

Original Assignee

Kureha Corp

Priority date

1980-05-23

Filing date

1980-05-23

Publication date

1981-12-17

1980-05-23 Application filed by Kureha Corp filed Critical Kureha Corp

1980-05-23 Priority to JP6850780A priority Critical patent/JPS56164175A/ja

1980-06-27 Priority to US06/163,507 priority patent/US4363813A/en

1980-07-07 Priority to CA000355635A priority patent/CA1150272A/en

1980-07-08 Priority to IT23315/80A priority patent/IT1131682B/it

1980-07-08 Priority to GB8022292A priority patent/GB2056440B/en

1980-07-08 Priority to FR8015210A priority patent/FR2465729A1/fr

1980-07-09 Priority to ES493650A priority patent/ES8105987A1/es

1980-07-09 Priority to DE3026054A priority patent/DE3026054C2/de

1981-02-13 Priority to ES500076A priority patent/ES500076A0/es

1981-12-17 Publication of JPS56164175A publication Critical patent/JPS56164175A/ja

1982-12-03 Priority to CA000417020A priority patent/CA1158247A/en

1988-03-10 Publication of JPS6310950B2 publication Critical patent/JPS6310950B2/ja

Status Granted legal-status Critical Current

Links

208000025865 Ulcer Diseases 0.000 title abstract 2
230000002467 anti-pepsin effect Effects 0.000 title abstract 2
231100000397 ulcer Toxicity 0.000 title abstract 2
239000000470 constituent Substances 0.000 title 1
150000007979 thiazole derivatives Chemical class 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 4
125000000217 alkyl group Chemical group 0.000 abstract 2
239000000126 substance Substances 0.000 abstract 2
LVESFLBRVSDDPO-UHFFFAOYSA-N 2-(3,4,5-trimethoxyphenyl)-1,3-thiazole Chemical class COC1=C(OC)C(OC)=CC(C=2SC=CN=2)=C1 LVESFLBRVSDDPO-UHFFFAOYSA-N 0.000 abstract 1
125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
150000001408 amides Chemical class 0.000 abstract 1
239000002260 anti-inflammatory agent Substances 0.000 abstract 1
229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
239000003416 antiarrhythmic agent Substances 0.000 abstract 1
239000002220 antihypertensive agent Substances 0.000 abstract 1
239000000168 bronchodilator agent Substances 0.000 abstract 1
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
210000004211 gastric acid Anatomy 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
239000012442 inert solvent Substances 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
150000002923 oximes Chemical class 0.000 abstract 1
239000000810 peripheral vasodilating agent Substances 0.000 abstract 1
229960002116 peripheral vasodilator Drugs 0.000 abstract 1
230000028327 secretion Effects 0.000 abstract 1
150000007659 semicarbazones Chemical class 0.000 abstract 1
LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1