JPS5615267A - N2-arylsulfonyl-l-argininamide and its salt - Google Patents
N2-arylsulfonyl-l-argininamide and its saltInfo
- Publication number
- JPS5615267A JPS5615267A JP8878679A JP8878679A JPS5615267A JP S5615267 A JPS5615267 A JP S5615267A JP 8878679 A JP8878679 A JP 8878679A JP 8878679 A JP8878679 A JP 8878679A JP S5615267 A JPS5615267 A JP S5615267A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- salt
- residue
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000003839 salts Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- UQHCHLWYGMSPJC-UHFFFAOYSA-N 4-methylpiperidin-1-ium-2-carboxylate Chemical compound CC1CCNC(C(O)=O)C1 UQHCHLWYGMSPJC-UHFFFAOYSA-N 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000001407 anti-thrombic effect Effects 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000015271 coagulation Effects 0.000 abstract 1
- 238000005345 coagulation Methods 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- -1 polycyclic compound Chemical class 0.000 abstract 1
- 125000005493 quinolyl group Chemical group 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- 125000002088 tosyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])S(*)(=O)=O 0.000 abstract 1
Landscapes
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8878679A JPS5615267A (en) | 1979-07-13 | 1979-07-13 | N2-arylsulfonyl-l-argininamide and its salt |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8878679A JPS5615267A (en) | 1979-07-13 | 1979-07-13 | N2-arylsulfonyl-l-argininamide and its salt |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5615267A true JPS5615267A (en) | 1981-02-14 |
| JPS6148829B2 JPS6148829B2 (enrdf_load_stackoverflow) | 1986-10-25 |
Family
ID=13952522
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8878679A Granted JPS5615267A (en) | 1979-07-13 | 1979-07-13 | N2-arylsulfonyl-l-argininamide and its salt |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5615267A (enrdf_load_stackoverflow) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57133300A (en) * | 1981-02-10 | 1982-08-17 | Nippon Synthetic Chem Ind | Production of paper |
| JPH07196650A (ja) * | 1993-12-28 | 1995-08-01 | Dai Ichi Seiyaku Co Ltd | 平滑筋細胞増殖抑制作用を有するアルガトロバン製剤 |
| JP2014510117A (ja) * | 2011-04-04 | 2014-04-24 | ルンドベック ファーマシューティカルズ イタリー ソシエタ ペル アチオニ | アルガトロバン一水和物合成のためのプロセス中間体の製造方法 |
-
1979
- 1979-07-13 JP JP8878679A patent/JPS5615267A/ja active Granted
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57133300A (en) * | 1981-02-10 | 1982-08-17 | Nippon Synthetic Chem Ind | Production of paper |
| JPH07196650A (ja) * | 1993-12-28 | 1995-08-01 | Dai Ichi Seiyaku Co Ltd | 平滑筋細胞増殖抑制作用を有するアルガトロバン製剤 |
| JP2014510117A (ja) * | 2011-04-04 | 2014-04-24 | ルンドベック ファーマシューティカルズ イタリー ソシエタ ペル アチオニ | アルガトロバン一水和物合成のためのプロセス中間体の製造方法 |
| JP2017186350A (ja) * | 2011-04-04 | 2017-10-12 | ルンドベック ファーマシューティカルズ イタリー ソシエタ ペル アチオニ | アルガトロバン一水和物合成のためのプロセス中間体の製造方法 |
| US9994526B2 (en) | 2011-04-04 | 2018-06-12 | Lundbeck Pharmaceuticals Italy S.P.A. | Process intermediates and methods for the preparation of process intermediates for the synthesis of argatroban monohydrate |
| US10385020B2 (en) | 2011-04-04 | 2019-08-20 | Lundbeck Pharmaceuticals Italy S.P.A. | Process intermediates and methods for the preparation of process intermediates for the synthesis of argatroban monohydrate |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6148829B2 (enrdf_load_stackoverflow) | 1986-10-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EXPY | Cancellation because of completion of term | ||
| R154 | Certificate of patent or utility model (reissue) |
Free format text: JAPANESE INTERMEDIATE CODE: R154 |