JPS56128736A - Preparation of alpha-chloroethyl ethyl carbonate - Google Patents
Preparation of alpha-chloroethyl ethyl carbonateInfo
- Publication number
- JPS56128736A JPS56128736A JP3227180A JP3227180A JPS56128736A JP S56128736 A JPS56128736 A JP S56128736A JP 3227180 A JP3227180 A JP 3227180A JP 3227180 A JP3227180 A JP 3227180A JP S56128736 A JPS56128736 A JP S56128736A
- Authority
- JP
- Japan
- Prior art keywords
- dec
- under
- recover
- raw material
- scattered light
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To recover the titled monochloro compound in high yield, by blowing chlorine into liquid diethyl carbonate under the scattered light, etc., chlorinating the diethyl carbonate to a specific conversion, and distilling the reaction mixture.
CONSTITUTION: Chlorine is blown into liquid diethylcarbonate (DEC) under the scattered light or in the presence of an organic peroxide, e.g. benzoyl peroxide, in an amount of 0.1W5wt%, preferably 0.2W2wt%, based on the raw material DEC for the better reaction progress, at 0W100°C for 4W20hr, to chlorinate DEC to 40W90%, conversion thereof, preferably 60W80%, and the resultant reaction mixture is then distilled under the reduced pressure at 100°C or below, to recover the aimed compound. The reaction may be industrially and readily carried out in the dark in the presence of an organic peroxide.
USE: A raw material for a medicine, e.g. synthetic penicillin.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3227180A JPS5948818B2 (en) | 1980-03-14 | 1980-03-14 | Production method of α-chloroethyl ethyl carbonate |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3227180A JPS5948818B2 (en) | 1980-03-14 | 1980-03-14 | Production method of α-chloroethyl ethyl carbonate |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56128736A true JPS56128736A (en) | 1981-10-08 |
JPS5948818B2 JPS5948818B2 (en) | 1984-11-29 |
Family
ID=12354323
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3227180A Expired JPS5948818B2 (en) | 1980-03-14 | 1980-03-14 | Production method of α-chloroethyl ethyl carbonate |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5948818B2 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59122441A (en) * | 1982-11-04 | 1984-07-14 | アストラ・ラケメデル・アクチェボラグ | Novel 1-bromoethylethylcarbonate compound and manufacture |
US4820857A (en) * | 1982-09-20 | 1989-04-11 | Astra Lakemedel Aktiebolag | α-bromodiethylcarbonate |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103922938B (en) * | 2014-04-17 | 2016-01-20 | 湖北福尔嘉医药化工有限公司 | A kind of synthetic method of chloromethyl butylperoxyisopropyl carbonate |
-
1980
- 1980-03-14 JP JP3227180A patent/JPS5948818B2/en not_active Expired
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4820857A (en) * | 1982-09-20 | 1989-04-11 | Astra Lakemedel Aktiebolag | α-bromodiethylcarbonate |
JPS59122441A (en) * | 1982-11-04 | 1984-07-14 | アストラ・ラケメデル・アクチェボラグ | Novel 1-bromoethylethylcarbonate compound and manufacture |
Also Published As
Publication number | Publication date |
---|---|
JPS5948818B2 (en) | 1984-11-29 |
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