JPS56127364A - Novel piperazine compound, its preparation and utilization - Google Patents

Novel piperazine compound, its preparation and utilization

Info

Publication number
JPS56127364A
JPS56127364A JP2464880A JP2464880A JPS56127364A JP S56127364 A JPS56127364 A JP S56127364A JP 2464880 A JP2464880 A JP 2464880A JP 2464880 A JP2464880 A JP 2464880A JP S56127364 A JPS56127364 A JP S56127364A
Authority
JP
Japan
Prior art keywords
compound expressed
formula
piperazine compound
utilization
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2464880A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6254306B2 (en, 2012
Inventor
Isao Sakano
Shoichiro Miyahara
Yoshitsugu Yamada
Yutaka Okazaki
Hiroshi Tokuda
Akira Awaya
Takuo Nakano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Toatsu Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals Inc filed Critical Mitsui Toatsu Chemicals Inc
Priority to JP2464880A priority Critical patent/JPS56127364A/ja
Priority to GB8105618A priority patent/GB2070603B/en
Priority to DE3107594A priority patent/DE3107594C2/de
Priority to IT47904/81A priority patent/IT1170763B/it
Priority to FR8104092A priority patent/FR2477151B1/fr
Publication of JPS56127364A publication Critical patent/JPS56127364A/ja
Priority to US06/458,311 priority patent/US4476128A/en
Publication of JPS6254306B2 publication Critical patent/JPS6254306B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
JP2464880A 1980-03-01 1980-03-01 Novel piperazine compound, its preparation and utilization Granted JPS56127364A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP2464880A JPS56127364A (en) 1980-03-01 1980-03-01 Novel piperazine compound, its preparation and utilization
GB8105618A GB2070603B (en) 1980-03-01 1981-02-23 Piperazine compounds
DE3107594A DE3107594C2 (de) 1980-03-01 1981-02-27 Thiazolylpiperazin-Verbindungen, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Immunverstärker
IT47904/81A IT1170763B (it) 1980-03-01 1981-02-27 Composti di piperazina procedimento per prepararli e composizioni immunopotenziatrici che li contegono
FR8104092A FR2477151B1 (fr) 1980-03-01 1981-03-02 Derives de la piperazine, leur preparation et leurs utilisations en medecine
US06/458,311 US4476128A (en) 1980-03-01 1983-01-13 2-Substituted thiazolyl-piperazine compounds, process for preparation thereof and utilizations thereof _

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2464880A JPS56127364A (en) 1980-03-01 1980-03-01 Novel piperazine compound, its preparation and utilization

Publications (2)

Publication Number Publication Date
JPS56127364A true JPS56127364A (en) 1981-10-06
JPS6254306B2 JPS6254306B2 (en, 2012) 1987-11-13

Family

ID=12143953

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2464880A Granted JPS56127364A (en) 1980-03-01 1980-03-01 Novel piperazine compound, its preparation and utilization

Country Status (6)

Country Link
US (1) US4476128A (en, 2012)
JP (1) JPS56127364A (en, 2012)
DE (1) DE3107594C2 (en, 2012)
FR (1) FR2477151B1 (en, 2012)
GB (1) GB2070603B (en, 2012)
IT (1) IT1170763B (en, 2012)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56127364A (en) * 1980-03-01 1981-10-06 Mitsui Toatsu Chem Inc Novel piperazine compound, its preparation and utilization
NZ538225A (en) 2002-08-09 2008-05-30 Astrazeneca Ab "1,2,4"Oxadiazoles as modulators of metabotropic glutamate receptor-5
CN1691944A (zh) * 2002-08-09 2005-11-02 阿斯利康(瑞典)有限公司 作为代谢型谷氨酸受体－5调节剂的噁二唑
WO2004014902A2 (en) * 2002-08-09 2004-02-19 Astrazeneca Ab Compounds having an activity at metabotropic glutamate receptors
WO2005077373A2 (en) * 2004-02-03 2005-08-25 Astrazeneca Ab Treatment of gastro-esophageal reflux disease (gerd)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA533657A (en) * 1956-11-27 W. Stewart Hugh 1-carbamyl-4-thiazolyl piperazines
US2519715A (en) * 1947-11-12 1950-08-22 American Cyanamid Co 1-carbamyl-4-heterocyclopiperazines
US2602796A (en) * 1950-11-24 1952-07-08 American Cyanamid Co 1-carbamyl-4-thiazolyl piperazines
US2666055A (en) * 1952-10-27 1954-01-12 American Cyanamid Co 1-thiocarbamyl-4-heterocyclic piperazines
JPS56127364A (en) * 1980-03-01 1981-10-06 Mitsui Toatsu Chem Inc Novel piperazine compound, its preparation and utilization

Also Published As

Publication number Publication date
GB2070603A (en) 1981-09-09
IT1170763B (it) 1987-06-03
IT8147904A0 (it) 1981-02-27
FR2477151A1 (fr) 1981-09-04
DE3107594A1 (de) 1982-02-11
JPS6254306B2 (en, 2012) 1987-11-13
DE3107594C2 (de) 1984-04-26
GB2070603B (en) 1984-07-04
FR2477151B1 (fr) 1986-05-02
US4476128A (en) 1984-10-09

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