JPS5612366A - Novel substituted phenoxypropylamine derivative - Google Patents

Novel substituted phenoxypropylamine derivative

Info

Publication number
JPS5612366A
JPS5612366A JP8586079A JP8586079A JPS5612366A JP S5612366 A JPS5612366 A JP S5612366A JP 8586079 A JP8586079 A JP 8586079A JP 8586079 A JP8586079 A JP 8586079A JP S5612366 A JPS5612366 A JP S5612366A
Authority
JP
Japan
Prior art keywords
compound shown
formula
salt
novel substituted
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP8586079A
Other languages
Japanese (ja)
Other versions
JPS6341902B2 (en
Inventor
Takeo Shibata
Toshihisa Itaya
Nobuaki Yamagoshi
Shigeru Kurata
Naoyuki Koizumi
Masao Taruya
Hideki Sakuma
Kunihiro Konishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aska Pharmaceutical Co Ltd
Original Assignee
Teikoku Hormone Manufacturing Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teikoku Hormone Manufacturing Co Ltd filed Critical Teikoku Hormone Manufacturing Co Ltd
Priority to JP8586079A priority Critical patent/JPS5612366A/en
Publication of JPS5612366A publication Critical patent/JPS5612366A/en
Publication of JPS6341902B2 publication Critical patent/JPS6341902B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound shown by the formula I (R is H or methyl; Y is OH or hydroxymethyl-substituted 1-pyrrolidinyl or 1-piperidinyl; Z is =CH-NO2 or =N-CN) and its salt.
EXAMPLE: N-methyl-N'-[ 3-[3-(3-hydroxy-1-pyrrolidinylmethyl)phenoxy]propyl ]- 2-nitro-1,1-ethenediamine.
USE: A remedy for gastric ulcer and duodenal ulcer. Having inhibiting action on the secretion of acid in the stomach based on improved antagonism of histamine H2 receptor.
PROCESS: For example, a novel compound shown by the formula II or its salt is reacted with a compound shown by the formula III (R1 is lower alkyl) to give a reaction product. The product is converted into a salt, if necessary, to prepare a compound shown by the formula I (wherein Z is =CH-NO2).
COPYRIGHT: (C)1981,JPO&Japio
JP8586079A 1979-07-09 1979-07-09 Novel substituted phenoxypropylamine derivative Granted JPS5612366A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8586079A JPS5612366A (en) 1979-07-09 1979-07-09 Novel substituted phenoxypropylamine derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8586079A JPS5612366A (en) 1979-07-09 1979-07-09 Novel substituted phenoxypropylamine derivative

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2259587A Division JPS62246551A (en) 1987-02-04 1987-02-04 Novel substituted phenoxypropylamine derivative

Publications (2)

Publication Number Publication Date
JPS5612366A true JPS5612366A (en) 1981-02-06
JPS6341902B2 JPS6341902B2 (en) 1988-08-19

Family

ID=13870626

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8586079A Granted JPS5612366A (en) 1979-07-09 1979-07-09 Novel substituted phenoxypropylamine derivative

Country Status (1)

Country Link
JP (1) JPS5612366A (en)

Also Published As

Publication number Publication date
JPS6341902B2 (en) 1988-08-19

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