JPS5612366A - Novel substituted phenoxypropylamine derivative - Google Patents
Novel substituted phenoxypropylamine derivativeInfo
- Publication number
- JPS5612366A JPS5612366A JP8586079A JP8586079A JPS5612366A JP S5612366 A JPS5612366 A JP S5612366A JP 8586079 A JP8586079 A JP 8586079A JP 8586079 A JP8586079 A JP 8586079A JP S5612366 A JPS5612366 A JP S5612366A
- Authority
- JP
- Japan
- Prior art keywords
- compound shown
- formula
- salt
- novel substituted
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A compound shown by the formula I (R is H or methyl; Y is OH or hydroxymethyl-substituted 1-pyrrolidinyl or 1-piperidinyl; Z is =CH-NO2 or =N-CN) and its salt.
EXAMPLE: N-methyl-N'-[ 3-[3-(3-hydroxy-1-pyrrolidinylmethyl)phenoxy]propyl ]- 2-nitro-1,1-ethenediamine.
USE: A remedy for gastric ulcer and duodenal ulcer. Having inhibiting action on the secretion of acid in the stomach based on improved antagonism of histamine H2 receptor.
PROCESS: For example, a novel compound shown by the formula II or its salt is reacted with a compound shown by the formula III (R1 is lower alkyl) to give a reaction product. The product is converted into a salt, if necessary, to prepare a compound shown by the formula I (wherein Z is =CH-NO2).
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8586079A JPS5612366A (en) | 1979-07-09 | 1979-07-09 | Novel substituted phenoxypropylamine derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8586079A JPS5612366A (en) | 1979-07-09 | 1979-07-09 | Novel substituted phenoxypropylamine derivative |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2259587A Division JPS62246551A (en) | 1987-02-04 | 1987-02-04 | Novel substituted phenoxypropylamine derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5612366A true JPS5612366A (en) | 1981-02-06 |
JPS6341902B2 JPS6341902B2 (en) | 1988-08-19 |
Family
ID=13870626
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP8586079A Granted JPS5612366A (en) | 1979-07-09 | 1979-07-09 | Novel substituted phenoxypropylamine derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5612366A (en) |
-
1979
- 1979-07-09 JP JP8586079A patent/JPS5612366A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6341902B2 (en) | 1988-08-19 |
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